Accès ouvert
2024
article
OpenAlex
Dequan Wang, Jielian Wang, Fei Yao, Zhufu Xie et autres
The effectiveness of chemotherapy involving 5-fluorouracil and cisplatin (DDP) for the treatment of colorectal cancer (CRC) is often limited due to the emergence of drug resistance. An increasing body of research highlights the crucial role of abnormally expressed microRNAs (miR/miRNAs) in fostering …
cn
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Accès ouvert
2023
article
OpenAlex
Zhufu Xie, Rui Zhu, Xiaoying Huang, Fei Yao et autres
Colorectal cancer (CRC) is one of the leading global malignancies with low 5-year survival and high mortality rates. Despite extensive research, the precise role of gut metabolites in CRC development and clinical outcomes remains unclear, while its elucidation may aid the development …
cn
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Accès ouvert
2022
article
OpenAlex
Fei Yao, Xiaoying Huang, Zhufu Xie, Jie Chen et autres
Chemoresistance is a huge clinical challenge in the treatment of advanced colorectal cancer (CRC). Non-coding RNAs (ncRNAs) and messenger RNA (mRNA) are involved in CRC chemoresistance. However, the profiles of long ncRNAs (lncRNAs), microRNAs (miRNAs), mRNAs and competing endogenous RNA (ceRNA) networks …
cn
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Accès ouvert
2021
article
OpenAlex
Fei Yao, Xiaochen Xiang, Chuanren Zhou, Qiyou Huang et autres
Chemoresistance is a major clinical obstacle for the treatment of colorectal cancer (CRC). Circular RNAs (circRNAs) are a new type of non-coding RNA that participated in the development of chemoresistance. However, the profiles and effects of circRNAs in 5-fluorouracil (5-Fu) and cisplatin …
cn
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