Xiangtian Liu

VEGF ameliorates acute kidney injury by suppressing ferroptosis through activation of the ERK1/2-NRF2 pathway

Xiangtian Liu, Yuqi Song, Liping Ye, Dongxiao Li et autres

Vascular endothelial growth factor (VEGF) plays a crucial role in maintaining renal homeostasis. However, the precise impact of VEGF on ferroptosis in acute kidney injury (AKI) remains incompletely understood. This study aims to investigate the effects of VEGF on ferroptosis in the …

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BAP31 promotes breast cancer progression by interaction with SERCA2

Xiangtian Liu, Qiao Ping Xu, Wenchang Qian, Haiyang Guan et autres

Abstract Background B-Cell receptor-associated protein 31 (BAP31) is a resident chaperone protein in the endoplasmic reticulum. It was observed herein that a higher expression of BAP31 mRNA was associated with a worse prognosis in breast cancer patients. Methods Breast cancer cells and …

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Cancer Stem Cell Regulated Phenotypic Plasticity Protects Metastasized Cancer Cells from Ferroptosis

Mingming Wu, Xiao Zhang, Weijie Zhang, Yi‐Shiou Chiou et autres

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Hypermethylation of Mitochondrial Cytochrome b and Cytochrome c Oxidase II Genes with Decreased Mitochondrial DNA Copy Numbers in the APP/PS1 Transgenic Mouse Model of Alzheimer’s Disease

Yingying Xu, Ling Jie Cheng, Jing Sun, Fan Li et autres

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Transplantation of IFN-γ Primed hUCMSCs Significantly Improved Outcomes of Experimental Autoimmune Encephalomyelitis in a Mouse Model

Xiaoyan Zhou, Xiaoli Liu, Li Liu, Chao Han et autres

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Vascular endothelial growth factor alleviates mitochondrial dysfunction and suppression of mitochondrial biogenesis in models of Alzheimer’s disease

Xiangtian Liu, Bingcong Chu, Suqin Jin, Maoyu Li et autres

Purpose Mitochondrial dysfunction is a prominent feature of Alzheimer’s disease (AD). As vascular endothelial growth factor (VEGF) has been shown to be protective in AD, the aim of this study was to investigate the effects of VEGF on mitochondrial function in models …

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Orexin-A aggravates cytotoxicity and mitochondrial impairment in SH-SY5Y cells transfected with APPswe via p38 MAPK pathway

Maoyu Li, Yao Meng, Bingcong Chu, Yang Shen et autres

BACKGROUND: Alzheimer's disease (AD) is one of the common neurodegenerative diseases and is characterized by the accumulation of amyloid-β (Aβ). Orexin-A is a neuropeptide produced in the hypothalamus and thought to be involved in the pathogenesis of AD. However, its underlying mechanism …

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Orexin-A exacerbates Alzheimer’s disease by inducing mitochondrial impairment

Maoyu Li, Yao Meng, Bingcong Chu, Yang Shen et autres

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Altered mitochondrial DNA methylation and mitochondrial DNA copy number in an APP/PS1 transgenic mouse model of Alzheimer disease

Yingying Xu, Linlin Xu, Min Han, Xiangtian Liu et autres

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Mitochondrial biogenesis mediated by melatonin in an APPswe/PS1dE9 transgenic mice model

Chaoyuan Song, Maoyu Li, Linlin Xu, Yang Shen et autres

Alzheimer's disease (AD) is a chronic progressive neurodegenerative disease, but the pathogenesis is unclear. Damaged mitochondrial biogenesis has been observed in AD. Increasing evidence suggests that mitochondrial biogenesis is involved in the pathogenesis of AD, but the exact mechanism is unclear. In …

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A novel shift-multiply framework for one-dimensional chaotic map

Shu Jian Liang, Xiangtian Liu, Fengqi Yu

This paper introduces a shift-multiply framework to generate one-dimensional (1-D) chaotic maps using a combination of two 1-D chaotic maps (called seed maps). On the basis of conventional 1-D chaotic map, its iteration algorithm is improved which enhances the ability of anti-dawning. …

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A Doppler shift estimation algorithm with low computational complexity for underwater acoustic communication

Jie Yang, Xiangtian Liu, Fengqi Yu

In underwater acoustic communication system, carrier synchronization and symbol synchronization are adversely affected by Doppler Effect, due to relative motion of the transmitter and receiver. This paper presents a novel Doppler shift factor estimation algorithm. That is the joint estimation of frequency …

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