Charles D. Kassardjian

The Fiscal Consequences for the Canadian Government of Efgartigimod in the Treatment of Generalized Myasthenia Gravis

A.T. Paquete, Mark P. Connolly, Cynthia Z. Qi, Hans Katzberg et autres

Background: Generalized myasthenia gravis (gMG) severely impacts activities of daily living. Productivity losses and the need for care can impact household finances and consequently government public accounts. This study adopts a governmental perspective framework to assess the fiscal consequences of treating gMG …

be, ca (code pays fourni par la source)

The Fiscal Consequences for the Canadian Government of Efgartigimod in the Treatment of Generalized Myasthenia Gravis

A.T. Paquete, Mark Connolly, Cynthia Qi, Hans Katzberg et autres

Background: Generalized myasthenia gravis (gMG) severely impacts activities of daily living. Productivity losses and the need for care can impact household finances and consequently government public accounts. This study adopts a governmental perspective framework to assess the fiscal consequences of treating gMG …

Reviewer Comment on Cooper et al. “Exploring the Value of Brain T2* Weighted and FLAIR Imaging for Diagnosing Amyotrophic Lateral Sclerosis”

Ario Mirian, Charles D. Kassardjian

ca (code pays fourni par la source)

Practice Pearls: Spinal Myxopapillary Ependymoma Masquerading as Charcot-Marie Tooth (CMT) Disease

Kate McMullen, Moises Maria, Charles D. Kassardjian

Practice Pearls:1. Heel-walking vs. toe-walking: In Charcot-Marie-Tooth disease (CMT), ankle dorsiflexion is most commonly weaker than plantarflexion.The ability to walk on the heels but not the

ca, us (code pays fourni par la source)

Virtual EMG : Safe and Effective Remote Supervision and Reporting

Khadija Brouillette, Corey Bacher, Charles D. Kassardjian

The COVID-19 pandemic accelerated the implementation of virtual care in healthcare, revealing challenges and opportunities in the use of remote healthcare services. Electromyography (EMG) traditionally requires in-person interaction, limiting access for patients in remote or underserved areas. This study explores the feasibility …

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EE527 Therapeutic Options for Changing the Course of Disease in Generalized Myasthenia Gravis (gMG) and Fiscal Consequences for the Canadian Governments

Qi Zhang, A.T. Paquete, Hans Dieter Katzberg, Syed Ali Raza et autres

ca, gb, nl, us, gr, be (code pays fourni par la source)

Idiopathic Inflammatory Myopathies and Malignancy Screening: A Survey of Current Practices Amongst Canadian Neurologists and Rheumatologists

Maria Jekielek, Rosane Nisenbaum, Ophir Vinik, Charles D. Kassardjian

INTRODUCTION/AIMS: Although the need for malignancy screening in idiopathic inflammatory myopathies (IIM) is generally accepted, data to guide the choice and timing of investigations are limited. Our aim was to characterize the gaps and uncertainties amongst Canadian neurologists and rheumatologists with respect …

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D.6 Changes in intravenous or subcutaneous immunoglobulin usage before and after efgartigimod initiation in patients with Myasthenia Gravis

Charles D. Kassardjian, Chunzhi Qi, Pushpa Narayanaswami, Andrew Paul Smith et autres

Background: While efgartigimod usage is expected to reduce immunoglobulin (IG) utilization, evidence in clinical practice is limited. Methods: In this retrospective cohort study, patients with gMG treated with efgartigimod for ≥1-year were identified from US medical/pharmacy claims data (April 2016-January 2024) and …

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P.105 Therapeutic options for changing the course of disease in generalized myasthenia gravis (gMG) and fiscal consequences for Canadian governments

Hans Dieter Katzberg, Qi Chang, A.T. Paquete, ST Raza et autres

Background: Generalized myasthenia gravis (gMG) is a potentially life threatening chronic autoimmune disease that can impair patients’ ability to work effectively and increase reliance on public support benefits. A public economic framework was used to explore how treatment influences patients’ and caregivers’ …

ca (code pays fourni par la source)

International Consensus Guidance for the Management of Glucocorticoid Related Complications in Neuromuscular Disease

Corey Bacher, Pushpa Narayanaswami, Mark B. Bromberg, Frank Buttgereit et autres

INTRODUCTION/AIMS: Glucocorticoid (GC)-related adverse reactions and risks are commonly seen during the treatment of immune-mediated and inflammatory neuromuscular disorders. There is wide variation in the management of associated complications. The aim of this study is to develop international consensus guidance on the …

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Virtual Compared With In-Person Neurologic Examination Study

Lauren Hophing, Tiffany Tse, Nicole Naimer, Mario Masellis et autres

Background and Objectives: The COVID-19 pandemic forced a shift to virtual care in several neurologic care settings. Little is known about the validity of the virtual neurologic examination (VNE) for clinical decision making when compared with the in-person neurologic examination (IPNE). The …

ca, gb (code pays fourni par la source)

Chronic glucocorticoid management in neuromuscular disease: A survey of neuromuscular neurologists

Lora Stepanian, Ruple S. Laughlin, Corey Bacher, Aaron Izenberg et autres

INTRODUCTION/AIMS: Glucocorticoids (GC) are first-line therapy for many neuromuscular diseases. There is a lack of guidelines regarding the prevention and management of GC complications in the context of neuromuscular disease, introducing the potential for practice variation, that may compromise quality of care. …

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