Elsa Toumi

Microdissection of Distinct Morphological Regions Within Uveal Melanomas Identifies Novel Drug Targets

Elsa Toumi, Luke B. Hesson, Vivian Lin, Dale Wright et autres

Background/Objectives: Uveal melanomas (UMs) are rare but often deadly malignancies that urgently require viable treatment options. UMs often exhibit tumour heterogeneity, with macroscopic and microscopic differences in morphology between different regions of the same tumour. However, to date, the clinical significance of …

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Visual Outcomes after Spontaneous and Surgical Closure of Small Idiopathic Macular Holes: A Comparative Study

Elsa Toumi, Damien Guindolet, Sophie Bonnin, Sébastien Bruneau et autres

INTRODUCTION: Small full-thickness macular holes (FTMHs) are classically treated surgically but can also occasionally close spontaneously. Long-term visual outcomes of spontaneously closed FTMHs are not well described. We compared best-corrected visual acuity (BCVA) after surgical and spontaneous closure of idiopathic FTMH (IMHs) …

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Benefit of Optical Coherence Tomography–Angiography in Patients Undergoing Transsphenoidal Pituitary Adenoma Surgery: A Prospective Controlled Study

Elsa Toumi, Fabien Almairac, Lydiane Mondot, Albert Themelin et autres

BACKGROUND: Although visual field (VF) defects are common in compressive pituitary adenoma (CPA), their pathophysiology has not been fully elucidated. The mechanical theory (i.e., direct compression of the optic chiasm by the CPA) and the vascular theory (i.e., compression of the vessels …

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(225) Female Sexual Function During the Last Trimester of Pregnancy

O Kaabia, Elsa Toumi

Abstract Introduction Since antiquity and until today, sexuality remains a taboo and complex subject, often little discussed either in private circles or with healthcare professionals. Although advertising and the media sometimes use it to attract attention, sexuality is still synonymous with the …

OCT-angiography for the diagnosis of radiation maculopathy in patients treated with proton beam therapy: A 2-year prospective study

L. Landa Marin, Elsa Toumi, Jean‐Pierre Caujolle, J. Doyen et autres

PURPOSE: Radiation maculopathy (RM) is the leading cause of visual acuity (VA) loss after proton beam therapy (PBT) of choroidal melanoma. The aim of this study was to assess the value of optical coherence tomography-angiography (OCT-A) for the diagnosis of RM in …

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Biopsy for molecular risk stratification in uveal melanoma: Yields and molecular characteristics in 119 patients

Vivian Lin, In Young Chung, Elsa Toumi, Daniel J. McKay et autres

Abstract Background Prognostic cytological and molecular features of uveal melanoma have been well researched and are essential in management. Samples can be obtained in vivo through fine needle aspirate biopsy, vitrector cutter, forceps or post‐enucleation for off‐site testing. This study aims to …

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Development of new therapeutic options for the treatment of uveal melanoma

Janney Z. Wang, Vivian Lin, Elsa Toumi, Ke Wang et autres

Uveal melanoma (UM) is the most common primary intraocular malignancy in adults. Important cytogenetic and genetic risk factors for the development of UM include chromosome 3 monosomy, mutations in the guanine nucleotide-binding proteins GNAQ/GNA11, and loss of the BRACA1-associated protein 1 (BAP …

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Lymphome du manteau orbitaire traité avec succès par un inhibiteur de Bcl-2 : à propos d’un cas

Elsa Toumi, Frédéric Peyrade, Stéphane Nahon, Luis Marín et autres

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Bases anatomiques de la voie rétro-caronculaire et ses applications cliniques en oculoplastique : étude sur cadavre

Leidy Carolina Sicachá Marín, Sacha Nahon‐Estève, Stéphanie Baillif, Elsa Toumi et autres

Décrire les rapports anatomiques de la voie d’abord rétro-caronculaire ainsi que des ses applications cliniques en oculoplastique à partir d’une étude conduite au laboratoire d’anatomie. Huit orbites provenant de 4 cadavres frais ont été disséquées au laboratoire d’anatomie de la faculté de …

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