Rosanna Filosa

Corrigendum to “Evaluation of molecular mechanisms of (Z)-3-(pentadec-10′-enyl)-catechol (litreol) and synthetic derivatives as inhibitors of human leukotriene biosynthesis” [Redox Biol. 87 (2025) 103880]

Alessia Maria Cossu, Simona Pace, Ferdinando Bruno, Lucia Abbatiello et autres

Corrigendum to "Evaluation of molecular mechanisms of (Z)-3-(pentadec-10'-enyl)-catechol (litreol) and synthetic derivatives as inhibitors of human leukotriene biosynthesis" [Redox Biol. 87 (2025) 103880]

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Evaluation of molecular mechanisms of (Z)-3-(pentadec-10′-enyl)-catechol (litreol) and synthetic derivatives as inhibitors of human leukotriene biosynthesis

Alessia Maria Cossu, Simona Pace, Ferdinando F. Bruno, Lucia Abbatiello et autres

5-Lipoxygenase (5-LO) catalyzes the early steps of leukotriene (LT) biosynthesis, making it an attractive target for anti-inflammatory drug development. This study providesa more detailed evaluation of the molecular mechanisms andpharmacological effects of litreol (CI), a natural compound from the Anacardiaceae family, along …

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Mechanistic Insights into the Therapeutic Role of Curcumin in Leukemia: Molecular Targets and Clinical Implications

Rajan Logesh, Waqas Alam, Khalaf F. Alsharif, Rosanna Filosa et autres

Leukemia is one of the most widespread and life-threatening malignancies that originates in the blood and bone marrow. Despite advances in treatment, there remains a need for safer and more effective therapeutic agents with fewer side effects. This review investigates the therapeutic …

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Bioactive peptides in Endodontic infections: The Good, The Bad, and The Ugly

Neeraj Choudhary, Devesh Tewari, Seyed Fazel Nabavi, Rosanna Filosa et autres

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Lower pain, less itching, and faster healing after ultrasound scalpel-assisted hemorrhoidectomy using an intimate cleaner containing chlorhexidine, acid hyaluronic acid, and natural anti-inflammatories: a multicenter observational case-control study

Antonio Brillantino, Luigi Marano, Maurizio Grillo, Alessio Palumbo et autres

PURPOSE: Postoperative pain is a major concern for patients undergoing ultrasound scalpel-assisted hemorrhoidectomy, potentially exacerbated by delayed wound healing. This study aimed to evaluate the impact of an intimate cleansing gel containing chlorhexidine, hyaluronic acid, and other anti-inflammatory agents (Antroclean Fisioderm) on …

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In Vitro Biological Activities of Paederia grandidieri Leaf Extracts

Faratiana Jenny Rasoariseheno, Nicoletta Fidanza, Elena Coccia, Dyana Jackson Ratovomanarivo et autres

In many developing countries, human health problems are solved using local plants. Knowledge of their chemical composition and biological activities can contribute to the creation of natural-based products usefully employed in human health. In this work, we analysed Paederia grandidieri leaves extracted …

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Paederia grandidieri Leaf Extracts: Polyphenols and Biological Activities

Faratiana Jenny Rasoarisheno, Nicoletta Fidanza, Elena Coccia, Dyana Jackson Ratovomanarivo et autres

In many developing countries human health problems are solved using local plants. Knowledge of their chemical composition and biological activities can contribute to the creation of natural-based products usefully employed in human health. In this work, we analyzed Paederia grandidieri leaves extracted …

Unlocking daidzein's healing power: Present applications and future possibilities in phytomedicine

Pouya Goleij, Pantea Majma Sanaye, Waqas Alam, Junmin Zhang et autres

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Exploiting new strategies in combating head and neck carcinoma: A comprehensive review on phytochemical approaches passing through PI3K /Akt/ mTOR signaling pathway

Amin Iranpanah, Mohammad Bagher Majnooni, Hossein Biganeh, Roshanak Amirian et autres

Recently, malignant neoplasms have growingly caused human morbidity and mortality. Head and neck cancer (HNC) constitutes a substantial group of malignancies occurring in various anatomical regions of the head and neck, including lips, mouth, throat, larynx, nose, sinuses, oropharynx, hypopharynx, nasopharynx, and …

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Evaluation of Molecular Mechanisms of (Z)-3-(Pentadec-10’-Enyl)-Catechol (Litreol) and Synthetic Derivatives as Inhibitors of Human Leukotriene Biosynthesis

Rosanna Filosa, Alessia Maria Cossu, Pace Simona, Ferdinando F. Bruno et autres

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Marine Cyanobacterial Peptides in Neuroblastoma: Search for Better Therapeutic Options

Salman Ahmed, Waqas Alam, Michael Aschner, Rosanna Filosa et autres

Neuroblastoma is the most prevalent extracranial solid tumor in pediatric patients, originating from sympathetic nervous system cells. Metastasis can be observed in approximately 70% of individuals after diagnosis, and the prognosis is poor. The current care methods used, which include surgical removal …

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Cardiac and Pulmonary Rehabilitation: Two Underutilized Approaches with Some Unexpected Benefits

Pasquale Ambrosino, Giuseppina Marcuccio, Roberto Formisano, Laura Marcuccio et autres

Although still underutilized [...].

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