Hye-Jin Jeong

Differential white matter development and cognitive abilities in the infant born very preterm: a 6-year follow-up study

Hye-Jin Jeong, So‐Yeon Shim, Hye Jung Cho

Motivation: Children born very preterm are at significant risk for neurodevelopmental impairments. However, an integrated understanding of these abnormalities remains unclear. Goal(s): This study aimed to identify differences in white matter development and cognitive abilities in children born very preterm compared to …

Refractory Multiple Myeloma in a West Highland White Terrier: Clinical Presentations and Therapeutic Interventions

Hyomi Jang, Hye-Jin Jeong, Ahyeon Sung, Jong‐In Kim et autres

This report presents the case of a seven-year-old West Highland White Terrier diagnosed with relapsed and refractory multiple myeloma (MM), managed using multiple treatment approaches, including conventional chemotherapy (melphalan, vincristine, doxorubicin, and dexamethasone), radiation therapy (RT), and novel agents such as the …

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Altered association of cortical thickness with cognitive abilities in very preterm children at 6 years of age

Hye-Jin Jeong, Uk-Su Choi, Sehee Shim

Motivation: Very preterm children have a risk of impaired cognitive function mediated by several risk factors. The association between structural alteration and high-order cognitive function remains unclear. Goal(s): Very preterm children at 6 years old showed significant differences in cortical thickness associated …

Association between cortical thickness and cognitive ability in very preterm school-age children

Uk-Su Choi, So‐Yeon Shim, Hye Jung Cho, Hye-Jin Jeong

Very preterm children, born before 32 weeks of gestation, are at risk for impaired cognitive function, mediated by several risk factors. Cognitive impairment can be measured by various neurodevelopmental assessments and is closely associated with structural alterations of brain morphometry, such as …

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Resting-state functional connectivity differences in preterm and term born children at school age

Hye-Jin Jeong, Hye Jung Cho, So‐Yeon Shim, Chan-A Park

Children born preterm are at a significant risk of neurodevelopmental impairment. Alterations of functional connectivity in higher-order association cortices after preterm birth might reflect cognitive or behavior problems in school-aged children born preterm. Our results will help understanding the pathophysiology of cognitive …

Altered functional connectivity in children born very preterm at school age

Hye Jung Cho, Hye-Jin Jeong, Chan-A Park, Dong Woo Son et autres

Children born very preterm are at significant risk of neurodevelopmental impairment. This study sought to identify differences in cognitive function in children born very preterm compared to term-born controls and investigate alteration in white matter microstructure and functional connectivity (FC) based on …

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Intelligence and Brain White Matter Development in Extremely Preterm Children at 6 Years Old Compared with Very Preterm Children

Hye Jung Cho, Hye-Jin Jeong, Mira Chung, So‐Yeon Shim

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[18F]THK5351 PET Imaging in Patients with Mild Cognitive Impairment

Hye-Jin Jeong, Hyon Lee, Sang‐Yoon Lee, Seongho Seo et autres

BACKGROUND AND PURPOSE: Mild cognitive impairment (MCI) is a condition with diverse clinical outcomes and subgroups. Here we investigated the topographic distribution of tau in vivo using the positron emission tomography (PET) tracer [¹⁸F]THK5351 in MCI subgroups. METHODS: This study included 96 …

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Relationships between [18F]-THK5351 Retention and Language Functions in Primary Progressive Aphasia

Hye-Jin Jeong, Cindy W. Yoon, Seongho Seo, Sang‐Yoon Lee et autres

BACKGROUND AND PURPOSE: There are three distinct subtypes of primary progressive aphasia (PPA): the nonfluent/agrammatic variant (nfvPPA), the semantic variant (svPPA), and the logopenic variant (lvPPA). We sought to characterize the pattern of [¹⁸F]-THK5351 retention across all three subtypes and determine the …

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18F-THK5351 PET Imaging in Nonfluent-Agrammatic Variant Primary Progressive Aphasia

Cindy W. Yoon, Hye-Jin Jeong, Seongho Seo, Sang‐Yoon Lee et autres

Background and Purpose: To analyze 18 F-THK5351 positron emission tomography (PET) scans of patients with clinically diagnosed nonfluent/agrammatic variant primary progressive aphasia (navPPA).Methods: Thirty-one participants, including those with Alzheimer's disease (AD, n=13), navPPA (n=3), and those with normal control (NC, n=15) who …

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18F-THK5351 PET Imaging in the Behavioral Variant of Frontotemporal Dementia

Gijin Nam, Hye-Jin Jeong, Jae Myeong Kang, Sang‐Yoon Lee et autres

BACKGROUND AND PURPOSE: F-THK5351 positron emission tomography (PET) scans, which were recently developed tau PET, in patients with clinically-diagnosed bvFTD. METHODS: F-THK5351 PET scans, and detailed neuropsychological tests were included in the study. Voxel-wise statistical analysis and region of interest (ROI)-based analyses …

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Functional variation of SHP-2 promoter is associated with preterm birth and delayed myelination and motor development in preterm infants

So‐Yeon Shim, Hye-Jin Jeong, Hyojin Park, Eun Young Kwon et autres

Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP-2) is a cytoplasmic tyrosine phosphatase that is highly expressed in hematopoietic cells and in the CNS and exerts opposite effects on signal transduction by exerting a neuroprotective or proapoptotic effect. Several mutations of …

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