Damiano Catucci

Liver MRI with T1 and T2 parametric mapping to characterize patients with primary sclerosing cholangitis

A Huber, Samuel Erb, Marie Ardoino, Damiano Catucci et autres

Purpose: The diagnosis of primary sclerosing cholangitis remains difficult, particularly in the absence of typical bile duct strictures. This study aims to assess the diagnostic performance of MRI T1 and T2 mapping with regard to differentiating PSC patients from matched controls. Materials …

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Detection and severity stratification of chronic liver disease using magnetic resonance intravoxel incoherent motion and elastography

Damiano Catucci, Sandro Urs von Daeniken, Verena Carola Obmann, Annalisa Berzigotti et autres

Abstract Background With chronic liver disease (CLD) rising globally, noninvasive methods are needed to stratify early, intermediate, and advanced CLD with and without clinically significant portal hypertension (CSPH). Purpose To analyze the combined diagnostic value of intravoxel incoherent motion (IVIM) and liver …

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Automated quantification of T1 and T2 relaxation times in liver mpMRI using deep learning: a sequence-adaptive approach

Lukas Zbinden, Damiano Catucci, Lars Doorenbos, Leona Hulbert et autres

OBJECTIVES: To evaluate a deep learning sequence-adaptive liver multiparametric MRI (mpMRI) assessment with validation in different populations using total and segmental T1 and T2 relaxation time maps. METHODS: A neural network was trained to label liver segmental parenchyma and its vessels on …

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Association of MRI-derived Segmental Nonfunctional Liver Volume and Chronic Liver Disease

Marie Ardoino, Lukas Zbinden, Jeremias Klaus, Alan A. Peters et autres

Abstract To determine whether the nonfunctional liver volume (NFLV) is an indicator of chronic liver disease (CLD). Multiparametric 3T abdominal MRI examinations enhanced with gadobenate dimeglumine of 51 patients were included in the study and divided into two groups: patients with (n=20) …

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Liver segmental volumes and their relationship with 5-year prognostication

Damiano Catucci, Joris Hrycyk, Naomi F. Lange, Verena Carola Obmann et autres

PURPOSE: This study aimed to analyze the predictive value of caudate to right lobe ratio (CRL-R) and liver segmental volume ratio (LSVR) for chronic liver disease (CLD) on routine abdominal CT scans and their association with 5-year decompensation- and transplant-free survival. METHOD: …

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MRI Extracellular Volume Fraction in Liver Fibrosis—A Comparison of Different Time Points and Blood Pool Measurements

Verena Carola Obmann, Marie Ardoino, Jeremias Klaus, Damiano Catucci et autres

BACKGROUND: Extracellular volume (ECV) correlates with the degree of liver fibrosis. PURPOSE: To analyze the performance of liver MRI-based ECV evaluations with different blood pool measurements at different time points. STUDY TYPE: Prospective. SAMPLE: 73 consecutive patients (n = 31 females, mean …

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Automated liver segmental volume ratio quantification on non-contrast T1–Vibe Dixon liver MRI using deep learning

Lukas Zbinden, Damiano Catucci, Yannick Suter, Leona Hulbert et autres

PURPOSE: To evaluate the effectiveness of automated liver segmental volume quantification and calculation of the liver segmental volume ratio (LSVR) on a non-contrast T1-vibe Dixon liver MRI sequence using a deep learning segmentation pipeline. METHOD: A dataset of 200 liver MRI with …

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Convolutional neural network for automated segmentation of the liver and its vessels on non-contrast T1 vibe Dixon acquisitions

Lukas Zbinden, Damiano Catucci, Yannick Suter, Annalisa Berzigotti et autres

We evaluated the effectiveness of automated segmentation of the liver and its vessels with a convolutional neural network on non-contrast T1 vibe Dixon acquisitions. A dataset of non-contrast T1 vibe Dixon liver magnetic resonance images was labelled slice-by-slice for the outer liver …

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T1 reduction rate with Gd-EOB-DTPA determines liver function on both 1.5 T and 3 T MRI

Verena Carola Obmann, Damiano Catucci, Annalisa Berzigotti, Christoph Gräni et autres

Magnetic resonance T1 mapping before and after Gd-EOB-DTPA administration allows quantification of the T1 reduction rate as a non-invasive surrogate marker of liver function. A major limitation of T1 relaxation time measurement is its dependency on MRI field strengths. Since T1 reduction …

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Noninvasive assessment of clinically significant portal hypertension using ΔT1 of the liver and spleen and ECV of the spleen on routine Gd-EOB-DTPA liver MRI

Damiano Catucci, Verena Carola Obmann, Annalisa Berzigotti, Christoph Gräni et autres

PURPOSE: To analyze the predictive value of ΔT1 of the liver and spleen as well as the extracellular volume fraction (ECV) of the spleen as noninvasive biomarkers for the determination of clinically significant portal hypertension (CSPH) on routine Gd-EOB-DTPA liver MRI. METHOD: …

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T1 mapping of the liver and the spleen in patients with liver fibrosis—does normalization to the blood pool increase the predictive value?

Verena Carola Obmann, Annalisa Berzigotti, Damiano Catucci, Lukas Ebner et autres

PURPOSE: To analyze whether the T1 relaxation time of the liver is a good predictor of significant liver fibrosis and whether normalization to the blood pool improves the predictive value. METHODS: This prospective study was conducted between 03/2016 and 02/2018. One hundred …

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Mapping of the liver function - impact of MR field strength on T1 reduction rate

Damiano Catucci, Verena Carola Obmann, Annalisa Berzigotti, Joris Hrycyk et autres