Masahiro Toyokawa

Effect of recent SARS-CoV-2 infection on anti-spike protein immunoglobulin G II response after BNT162b2 vaccination

Daiki Tanno, Yasuka Hara, Y. Sugaya, Koji Okuaki et autres

Objectives Our hospital experienced a SARS-CoV-2 outbreak 3 months before staff vaccination was initiated. This study compared antibody responses to the first and second doses of BNT162b2 mRNA vaccine among staff with and without prior infection. Methods Serum anti-spike (S) protein immunoglobulin …

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Evaluation of a nucleic acid amplification system, GENECUBE, for rapid detection of staphylococcal nuc and mecA in blood culture samples

Yasuka Hara, Daiki Tanno, Masahiro Toyokawa, Yukiko Takano et autres

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Validation of a modified enrichment broth for efficient screening of group B Streptococcus in pregnant women

Daiki Tanno, Kyoichi Saito, Yasuaki Tomii, Yukari Nakatsuka et autres

We validated a modified enrichment broth that changes its color when group B Streptococcus (GBS) grows. No GBS was detected in any of the non-yellow samples. Thus, the non-yellow samples were considered GBS-negative without conducting further examinations, potentially reducing medical costs and …

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In vitro activity of tedizolid against 43 species of Nocardia species

Masahiro Toyokawa, Noboru Ohana, Daiki Tanno, Minako Imai et autres

Abstract The purpose of the present study was to evaluate the in vitro activity of tedizolid against several clinically significant species of Nocardia by comparing with that of linezolid. A total of 286 isolates of Nocardia species, including 236 clinical isolates recovered …

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A Multicenter Study on the Utility of Selective Enrichment Broth for Detection of Group B Streptococcus in Pregnant Women in Japan

Daiki Tanno, Kyoichi Saito, Yasuaki Tomii, Yukari Nakatsuka et autres

Universal screening for Streptococcus agalactiae, Group B Streptococcus (GBS), in pregnant women is important for the prevention of severe infectious diseases in neonates. The subculture method using selective enrichment broth significantly improves GBS detection rates in the United States; however, this method …

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Nocardia sputorum sp. nov., an actinobacterium isolated from clinical specimens in Japan

Moriyuki Hamada, Narumi Enomoto, Tomonari Yamashita, Masahiro Shimojima et autres

Two novel actinobacteria, designated IFM 12276T and IFM 12275, were isolated from clinical specimens in Japan, and their taxonomic positions were investigated using a polyphasic approach. Phylogenetic analysis based on 16S rRNA gene sequence comparisons revealed that strains IFM 12276 T and …

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Detection of Clostridioides difficile toxin B gene in clinical stool specimens using rapid diagnostic quenching probe-polymerase chain reaction assay

Yasuka Hara, Kiwamu Nakamura, Daiki Tanno, Masahiro Toyokawa et autres

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Matrix-Assisted Laser Desorption Ionization–Time-of-Flight Mass Spectrometry with Time-of-Flight Peak Analysis for Rapid and Accurate Detection of Group B Streptococcus in Pregnant Women

Daiki Tanno, Kyoichi Saito, Kazutaka Ohashi, Masahiro Toyokawa et autres

As previously reported, 10%-30% of pregnant women carry Streptococcus agalactiae, Group B Streptococcus (GBS), in their vagina or rectum, and approximately 50% of them vertically transmit GBS to their neonates during labor or birth. Moreover, 1%-2% of the GBS-transmitted neonates develop severe …

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Identification and antimicrobial susceptibility profiles of Nocardia species clinically isolated in Japan

Masahiro Toyokawa, Noboru Ohana, Akiko Ueda, Minako Imai et autres

The aims of the present study were to profile the antimicrobial susceptibility patterns of a diverse range of Nocardia species isolated in Japan, and to determine the ability of matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) for species/complex identification. …

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COVID-19 Among Healthcare Workers: A Questionnaire Survey

Hiroyuki Kunishima, Toru Yoshikawa, Mayumi AMINAKA, Shiro ENDO et autres

Needlestick Injuries Among Healthcare Workers with COVID-19: A Questionnaire Survey

Hiroyuki Kunishima, Toru Yoshikawa, Mayumi AMINAKA, Shiro ENDO et autres

2) ・三鴨 廣繁 2)

Complete Genome Sequence of Multidrug-Resistant Strain Nocardia wallacei FMUON74, Isolated from a Sputum Culture

Masahiro Toyokawa, Makoto Taniguchi, Kazuma Uesaka, Keiko Nishimura

Nocardia wallacei is one of the members of the N. transvalensis complex which possess a highly unique susceptibility pattern. Here, we describe the closed complete genome sequence of the multidrug-resistant strain N. wallacei FMUON74, which was obtained using a hybrid approach combining …

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