Misato Kobayashi

Bronchial Physiological Saline Injection to Visualize Peripheral Pulmonary Lesions in Ultrathin Bronchoscopy

Mika Nakao, Tamio Okimoto, Noriaki Kurimoto, Ryosuke Tanino et autres

Background: During bronchial lavage, the lumen can be viewed better by injecting physiological saline into the bronchus. This study aimed to investigate the effect of injecting physiological saline into the bronchus while directly observing the bronchial lumen with peripheral pulmonary lesions using …

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Cytokine Release Syndrome More than Two Years after Pembrolizumab Introduction

Kazuhisa Nakashima, Kashu Kitani, Kento Kono, Ken Yoshihara et autres

A 71-year-old man with advanced lung adenocarcinoma was treated with carboplatin, pemetrexed, and pembrolizumab in June 2020. Pemetrexed and pembrolizumab maintenance therapy were continued until November 2022. A fever and severe fatigue occurred in December 2022; however, the cause of the infection …

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Comparison of Ultra-Magnifying Endocytoscopic and Hematoxylin-Eosin-Stained Images of Lung Specimens

Misato Kobayashi, Noriaki Kurimoto, Ryosuke Tanino, Yohei Shiratsuki et autres

Endocytoscopy enables real-time observation of lesions at ultra-magnification. In the gastrointestinal and respiratory fields, endocytoscopic images are similar to hematoxylin-eosin-stained images. This study aimed to compare the nuclear features of pulmonary lesions in endocytoscopic and hematoxylin-eosin-stained images. We performed an endocytoscopy to …

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Prognosis of frail older patients treated with intubation and artificial ventilation for respiratory failure

Kazuhisa Nakashima, Ken Yoshihara, Kento Kono, Mika Horie et autres

BACKGROUND: Older patients with severe respiratory failure have higher mortality rates and are more likely to experience impairments in activities of daily living (ADL). METHODS: We retrospectively reviewed patients (??75 years) who received intubation and artificial ventilation for respiratory failure at Shimane …

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Usefulness of endocytoscopy in evaluating transbronchial biopsy specimens

Takae Okuno, Noriaki Kurimoto, Akari Tanino, Megumi Hamaguchi et autres

BACKGROUND: Endocytoscopy (ECS) provides a magnification of approximately 450× for real-time observation of lesion nuclei. Using ECS, we aimed to evaluate whether sufficient samples for diagnosis can be obtained during bronchoscopy. We also investigated whether ECS can enable two-class diagnosis of malignant …

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Usefulness of endocytoscopy in evaluating transbronchial biopsy specimens

峰苗 奥野, 典昭 栗本, 明里 谷野, 愛 濱口 et autres

Ultra-magnifying Imaging of Thoracoscopic Biopsy Specimens Using Ex vivo Endocytoscopy in Three Patients with Mesothelioma

Yohei Shiratsuki, Noriaki Kurimoto, Yoshihiro Amano, Shunichi Hamaguchi et autres

We performed endocytoscopy (ECS) for the ex vivo evaluation of mesothelioma in specimens biopsied during medical thoracoscopy in three patients. We evaluated 19 biopsy specimens based on the density of nuclei and irregularity in the nuclei shape using ECS and compared them …

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An endobronchial hamartoma observed using narrow band imaging under saline injection: A case report

Misato Kobayashi, Noriaki Kurimoto, Yuki Mitarai, Takae Okuno et autres

Abstract A light blue line (LBL) was observed along the edge of a lesion using narrow band imaging under saline injection during bronchoscopy in an 82‐year‐old patient with a lobulated mass on the left B4. The histopathological diagnosis was hamartoma with ciliated …

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An endobronchial hamartoma observed using narrow band imaging under saline injection: A case report

Misato Kobayashi, 典昭 栗本, Yuki Mitarai, 峰苗 奥野 et autres

Acute Exacerbation of Tracheal Obstruction and Severe Respiratory Failure after a Single Dose of 2-Gy Irradiation for Squamous Cell Lung Carcinoma: A Case Report

Keita Kawakado, T Hotta, Jin Sakamoto, Mika Horie et autres

The patient, a 62-year-old woman, complained chiefly of cough. We planned chemoradiotherapy for squamous nonsmall cell lung cancer. A single dose of 2-Gy irradiation and no anticancer agent administration exacerbated the airway stenosis with severe respiratory failure. Urgent tracheal intubation was performed, …

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Nontuberculous Mycobacterium‐associated immune reconstitution inflammatory syndrome in a non‐HIV immunosuppressed patient

Misato Kobayashi, Yukari Tsubata, Yohei Shiratsuki, T Hotta et autres

Abstract A 69‐year‐old woman with rheumatoid arthritis, using immunosuppressants, including etanercept—a tumour necrosis factor (TNF)‐α antagonist—was referred to our hospital with fever and fatigue. Chest computed tomography revealed cavities in the left upper lobe. As Mycobacterium intracellulare infection was diagnosed, all immunosuppressants …

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Nontuberculous Mycobacterium-associated immune reconstitution inflammatory syndrome in a non-HIV immunosuppressed patient

Misato Kobayashi, 由佳里 津端, 白築 陽平, 尚誠 堀田 et autres