Hai Zeng

MRI radiomics combined with delta-radiomics model for predicting pathological complete response in locally advanced rectal cancer patients after neoadjuvant chemoradiotherapy: A multi-institutional study

Xuwei Tian, MA Ai-lin, Zhiqiang Jia, Busare Ruzeaiti et autres

PURPOSE: To construct and validate a magnetic resonance imaging (MRI) radiomics combined with delta-radiomics and clinical information (C) model for predicting pathological complete response (pCR) in patients with locally advanced rectal cancer (LARC) after neoadjuvant chemoradiotherapy (nCRT). METHODS: A total of 198 …

cn (code pays fourni par la source)

miR-103 promotes esophageal squamous cell carcinoma metastasis by targeting FOXP1

Min Huang, Jun Cai, Hai Zeng, Yan Zhu et autres

Esophageal squamous cell carcinoma (ESCC), a prevalent malignancy within the digestive tract, is associated with a significantly high mortality rate. MicroRNAs were already demonstrated to work in a wide range of tumors. The objective of the present research was to elucidate the …

cn (code pays fourni par la source)

Prospects and challenges of ovarian cancer organoids in chemotherapy research (Review)

Weijia Zhang, Yuqing Ding, Hui He, Keming Chen et autres

Ovarian cancer (OC), a prevalent and severe malignancy of the female reproductive system, often presents with mild early symptoms and is therefore diagnosed at advanced stages, leading to a poor prognosis. Current chemotherapeutic treatment relies on platinum-based combinational therapy and there have …

cn (code pays fourni par la source)

Small cell lung cancer with small intestinal metastasis: Case report and literature review

Hai Zeng, Min Zhu, Tiane Zhang

Patients with small cell lung cancer (SCLC) typically exhibit a poor prognosis, often receiving diagnoses at an advanced stage. Despite recent advances in immunotherapy, the median survival remains approximately one year. Gastrointestinal metastases from lung cancer, based on clinical experience, are exceedingly …

cn (code pays fourni par la source)

Beyond tumor‑associated macrophages involved in spheroid formation and dissemination: Novel insights for ovarian cancer therapy (Review)

Yuchen Liu, Hai Zeng, Ying Xiang

Ovarian cancer (OC) is the most common and deadly malignant tumor of the female reproductive system. When OC cells detach from the primary tumor and enter the ascitic microenvironment, they are present as individual cells or multicellular spheroids in ascites. These spheroids, …

cn (code pays fourni par la source)

MEST promotes immune escape in gastric cancer by downregulating MHCI expression via SHP2

Min Huang, Fan Zhang, Yan Zhu, Hai Zeng et autres

cn (code pays fourni par la source)

Supraclavicular lymph node metastasis should not be defined as regional lymph node metastasis in cervical and upper thoracic esophageal squamous cell carcinoma

Hai Zeng, Min Zhu, Yujiao Sun, Li Deng et autres

The importance of supraclavicular lymph node (SCLN) metastasis in cervical and upper thoracic esophageal squamous cell carcinoma (ESCC) has not been determined. The aim of the present study was to provide a detailed definition of the range of SCLN regions and to …

cn (code pays fourni par la source)

Exosomal miR‐196a‐5p contributes to esophageal squamous cell carcinoma malignant progression by inhibiting ITM2B

Min Huang, Shuang Li, Hai Zeng, Yan Zhu et autres

Exosomes from cancer cells function as carriers to spread or transport specific microRNAs (miRNAs) to distant sites to exert their effects, but the mechanism of exosomal miRNA action in esophageal squamous cell carcinoma (ESCC) has not been fully explained. Therefore, in this …

cn (code pays fourni par la source)

PLK3 is linked with higher tumor stage and unfavorable prognosis in patients with colorectal cancer

Hai Zeng, Qian Wang, Ying Xiang, Yameng Yang et autres

Objective: This study intended to explore the relationship of PLK3 with prognosis in patients with colorectal cancer (CRC). Methods: PLK3 positivity was detected by immunohistochemistry in 160 patients with CRC receiving surgical resection. Results: The median tumor PLK3-positive rate was 26.5%. Tumor …

cn (code pays fourni par la source)

Current and future perspectives in unresectable locally advanced esophageal squamous cell cancer (Review)

Weijia Zhang, Min Zhu, Ying Xiang, Yujiao Sun et autres

Definitive concurrent chemoradiotherapy has been the main standard treatment method for unresectable locally advanced esophageal squamous cell cancer (ESCC) since 1999. However, several disadvantages continue to be associated with this type of treatment, including a high local failure rate (reaching ~50% within …

cn (code pays fourni par la source)

Treatment options for neoadjuvant strategies of esophageal squamous cell carcinoma (Review)

Hai Zeng, Fan Zhang, Yujiao Sun, Shuang Li et autres

Compared with postoperative adjuvant therapy, neoadjuvant therapy has more potential advantages, such as decreasing tumor stage, killing micrometastatic cells. Because of these advantages, neoadjuvant therapy is recommended for numerous types of tumor, such as breast, lung and rectal cancer. To determine the …

cn (code pays fourni par la source)

Temporal trends in incidence and mortality of cervical cancer in China from 1990 to 2019 and predictions for 2034

Shuang Li, Min Mei Huang, Yan Zhu, Hai Zeng et autres

OBJECTIVE: This study aimed to analyze long-term trends of cervical cancer (CC) burden in China based on the GBD 2019 data and provide information and data support for formulating corresponding policies to control CC. METHODS: Incidence and mortality rate data of CC …

cn (code pays fourni par la source)