Afsaneh Orouji

Machine learning-powered high-dimensional optical sensing using Au@Ag nanorods for salivary thiocyanate and hypothiocyanite

Zeinab Feyzollahi, Afsaneh Orouji, Mohammad Reza Hormozi-Nezhad

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Multicolor detection of biothiols: machine learning-empowered plasmonic patterns recognition based on anti-etching of gold nanorods

Golara Akhondi, Afsaneh Orouji, M. Reza Hormozi-Nezhad

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Gold nanorods as multidimensional optical nanomaterials: machine learning-enhanced quantitative fingerprinting of proteins for diagnostic applications

Afsaneh Orouji, Mahdi Ghamsari, Samira Abbasi-Moayed, Mahmood Akbari et autres

-bromosuccinimide (NBS) can quickly etch AuNRs with a distinct color change, allowing convenient and accurate visual recognition of all amino acids. Herein, further explorations revealed that the presence of proteins, as amino acids' polymers, reduces the effective concentration of NBS to different …

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Machine learning-powered plasmonic pattern recognition: etch-suppressed gold nanorods for multiplex urinary analysis of catecholamine neurotransmitters

Mahsa Daneshmandi, Afsaneh Orouji, Mohammad Reza Hormozi-Nezhad

. The practical utility of the platform was validated through successful application to human urine samples, confirming its potential as a powerful tool for point-of-care diagnostics and clinical neurochemical analysis.

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Machine Learning-Empowered Multicolor Detection and Discrimination of Dopaminergic Agents: Utilizing Gold Nanorods for Generating Rainbow Signals

Zahra Hozhabr, Afsaneh Orouji, Mohammad Reza Hormozi-Nezhad

The demand for rapid and sensitive multianalyte detection of dopaminergic agents in assessing the progression of Parkinson’s disease (PD) has attracted recurring interest in recent years. In this study, a multicolor sensor was devised to multiplex detection and discrimination of levodopa ( …

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Morphology-dependent nanoplasmonic assay: a powerful signaling platform for multiplexed total antioxidant capacity analysis

Zeinab Feyzollahi, Mahdiye Hassanpoor, Afsaneh Orouji, Mohammad Reza Hormozi-Nezhad

for AA, CYS, GSH, UA, and TAC-mixture, respectively. Moreover, performance metrics highlight the robustness and efficacy of the probe in detecting and quantifying antioxidant levels in saliva samples. The efficacy of the developed multi-colorimetric probe was rigorously validated through the analysis of …

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Gold Nanorod Amalgamation: Machine Learning Empowered Discrimination of Biothiol and Thiol Ratios

Golara Akhondi, Afsaneh Orouji, Mohammad Reza Hormozi-Nezhad

Biothiols, characterized by thiol groups, exhibit remarkable affinity for certain metals, playing pivotal roles in intracellular and extracellular biological processes. Fluctuations in their levels profoundly impact overall physiological health. Despite the development of various probes for biothiol detection and quantification, their inability …

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Multicolorimetric Sensor Array Based on Silver Metallization of Gold Nanorods for Discriminating Dopaminergic Agents

Reza Koohsar, Afsaneh Orouji, Mohammad Reza Hormozi-Nezhad

Dopaminergic agents are compounds that modulate dopamine-related activity in the brain and peripheral nerves within the pathways on both sides of the blood-brain barrier. Atypical levels of them can precipitate a multitude of neurological disorders, whose timely diagnosis signifies not only stopping …

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Etched-suppressed gold nanorods providing highly distinctive plasmonic patterns: Towards multiplex analysis of neuroblastoma biomarkers

Amirhosein Miri, Afsaneh Orouji, Mohammad Reza Hormozi-Nezhad

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Fast and Facile Etching of Gold Nanorods by N-Halosuccinimides: Toward Multicolorimetric Identification and Quantification of 20 Natural Amino Acids

Mahdi Ghamsari, Afsaneh Orouji, Mohammad Reza Hormozi-Nezhad

Gold nanorods (AuNRs) have recently become fascinating chromophores in the field of colorimetric sensing because of their eye-catching rainbow colors along with the high dimensionality of their optical profile. The etching of AuNRs using an analyte-sensitive oxidizing agent is particularly an attractive …

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Multiplex Detection of Biogenic Amines for Meat Freshness Monitoring Using Nanoplasmonic Colorimetric Sensor Array

Samira Abbasi-Moayed, Afsaneh Orouji, Mohammad Reza Hormozi-Nezhad

Biogenic amines (BAs) were presented as significant markers for the evaluation of the spoilage of meat and meat products. In this work, a colorimetric sensor array was developed for the discrimination and detection of spermine (SP), spermidine (SD), histamine (HS), and tryptamine …

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Machine Learning-Assisted Colorimetric Assay Based on Au@Ag Nanorods for Chromium Speciation

Afsaneh Orouji, Forough Ghasemi, Mohammad Reza Hormozi-Nezhad

The oxidation state of an element significantly controls its toxicological impacts on biological ecosystems. Therefore, design of robust sensing strategies for multiplex detection of species with respect to their oxidation states or bonding conditions, i.e., chemical speciation, is quite consequential. Chromium (Cr) …

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