Weiguo Xu

Finite element analysis of medial meniscus tears and related surgical techniques with biomechanical validation

Chengyue Yu, Kexin Liu, Jingyu Zhang, Wenjun Zhao et autres

Introduction This study established finite element models of the knee incorporating radial and longitudinal meniscal tears and simulated corresponding surgical techniques to investigate the influence of different tear types, lengths, locations on stress distribution in the knee joint and evaluate the restorative …

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Corticosteroid-responsive portal lymphadenopathy mimicking malignant progression induced by furmonertinib in EGFR-mutated NSCLC: a case report

Nengyang Zhu, Long Guo, Jing Zhu, Weiguo Xu et autres

Background: Third-generation epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) are widely used in the treatment of NSCLC with EGFR mutations due to their efficacy and favourable safety profile. However, drug-induced liver injury (DILI) associated with targeted therapy may occasionally present with …

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Transarterial Chemoembolization Combined With Camrelizumab and Rivoceranib for Unresectable Hepatocellular Carcinoma (CHANCE2005/CARES-005): A Randomized Phase II Trial

Haidong Zhu, W. Fan, Chang Zhao, S. Wang et autres

PURPOSE: Transarterial chemoembolization (TACE) alone has shown limited efficacy in improving survival among patients with unresectable hepatocellular carcinoma (HCC). This phase II trial compared TACE combined with camrelizumab (anti-PD-1 antibody) and rivoceranib (vascular endothelial growth factor receptor 2 inhibitor) versus TACE in …

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Screening Biomarkers for Nerve Injury Using Weighted Gene Co‐Expression Network Analysis and Machine Learning

Shuming Cao, Chengyue Yu, Nana Wang, Jianhua Xu et autres

BACKGROUND: Nerve injury triggers complex molecular responses involving immune activation and neuronal damage, yet the key regulatory genes and their mechanisms remain poorly understood. Here, we integrated multi-transcriptomic datasets and machine learning to identify and validate novel biomarkers of nerve injury and …

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Comparison of the efficacy and safety of catheter-directed thrombolysis using different approaches in the treatment of deep venous thrombosis of the lower limbs

Yuankai Luo, Yong Li, Weiguo Xu, Jicai Ma et autres

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MRI-based machine-learning radiomics of the liver to predict liver-related events in hepatitis B virus-associated fibrosis

Yuankai Luo, Yaobo Wu, Huan Ren, Xiaofeng Wang et autres

BACKGROUND: The onset of liver-related events (LREs) in fibrosis indicates a poor prognosis and worsens patients' quality of life, making the prediction and early detection of LREs crucial. The aim of this study was to develop a radiomics model using liver magnetic …

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Biomaterial‐Based Emergency Intervention for Secondary Spinal Cord Injury

J.C. Li, Qingzheng Zhang, Zongtai Liu, Weiguo Xu et autres

Timely therapeutic interventions for acute spinal cord injury (SCI) are critical for enhancing long-term neurological and functional outcomes by limiting injury progression. However, current clinical strategies, such as methylprednisolone (MS) shock therapy and spinal decompression surgery, often yield suboptimal results. Moreover, MS …

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PANI/BiVO4 photoanode drived Fe-Br solar redox flow battery system for efficient solar energy conversion and storage

Jiangxin Wang, Yuancheng Zhong, Xu Zhang, Xianfeng Xu et autres

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Progress in pore design within 3D orthopedic scaffold printing and an assessment of osseointegration — Overview review and critical review

Miaomiao Gao, Jingyu Zhang, Chengke Li, Xiaoyi Wang et autres

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Tunnel anastomosis versus double tract jejunal interposition reconstruction after proximal gastrectomy: Study protocol of a multicenter prospective randomized controlled trial (Preprint)

Gang Li, Hao Ying Xu, Meng Wang, Jin Qiong Zhou et autres

BACKGROUND Tunnel anastomosis is a novel anastomotic technique for digestive tract reconstruction following proximal gastrectomy. Our previous retrospective study demonstrated its favorable antireflux effect. OBJECTIVE In this study, we will prospectively compare this technique with the currently more prevalent double tract jejunal …

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Carefix hexaxial spatial frame versus Ilizarov circular external fixator in treating high-energy tibial shaft fractures: a retrospective study

Zhiming Zhao, Chen Xu, Yabin Liu, Bowen Shi et autres

BACKGROUND: External fixation is an effective treatment for high-energy tibial shaft fractures (HETSFs), often with severe soft tissue damage. The purpose of this study was to provide preliminary insights into potential differences in clinical outcomes between the Carefix Hexaxial Spatial Frame (CHSF) …

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Oral g-C3N4-based nanosheets as a universal metal antagonist inhibit cuproptosis pathway for reversing inflammation and injury of Wilson's disease

Xiaoying Xu, Wei Zhao, Qiu Li, Fei Liu et autres

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