Nathalie Allou

Adherence patterns and their determinants to CFTR modulators in France

Oriane Talabart, Elia Eid, Marie Viprey, Violaine Fernandez et autres

Cystic fibrosis transmembrane conductance regulator modulators (CFTRm) represent a major therapeutic advance for patients with cystic fibrosis (pwCF). Given their oral administration and high efficacy, they may be better suited than other cystic fibrosis treatments to optimize long-term adherence, which is crucial …

fr (code pays fourni par la source)

Pathogenic respiratory microbiota in cystic fibrosis: impact of 2 years of triple CFTR modulator therapy

Caroline Demeule, Lucie Amoureux, Frédéric Huet, Nathalie Allou et autres

fr, re (code pays fourni par la source)

Immune dysregulation through longitudinal lymphocyte trajectories and their clinical determinants in hospitalized COVID-19 patients

José Pedro Cidade, Fabio Silvio Taccone, Luis Felipe Reyes, Laura Merson et autres

OBJECTIVE: Immune dysregulation plays a pivotal role in the pathophysiology of sepsis and COVID-19, with lymphopenia emerging as a consistent marker of severity and poor prognosis. However, most existing studies have assessed lymphocyte counts at isolated time points, limiting insights into their …

pt, gb, be, co, fr, id, dk, us (code pays fourni par la source)

Prévalence et incidence élevées de la sclérodermie systémique sur l’île de la Réunion : résultats de l’étude SCLERUN

A. Dubernet, C. Roussin, Nathalie Sultan-Bichat, A. Foucher et autres

re, fr, be (code pays fourni par la source)

High prevalence and incidence of systemic sclerosis in Reunion Island, a French multi-ethnical and tropical territory

Arthur Dubernet, Céline Roussin, Nathalie Sultan-Bichat, Aurélie Foucher et autres

OBJECTIVES: Systemic sclerosis' (SSc) prevalence varies according to geographical location, presumably in link with environmental and genetic factors. We sought to determine SSc prevalence and incidence on Reunion Island, a southern hemisphere territory characterised by multi-ethnic background. METHODS: We conducted a retrospective …

re, fr, be (code pays fourni par la source)

Seasonal and climatic influence on respiratory infections in children with cystic fibrosis

Julie Mésinèle, Manon Ruffin, Loïc Guillot, Pierre‐Yves Boëlle et autres

Pseudomonas aeruginosa (Pa) and Methicillin susceptible Staphylococcus aureus (MSSA) are the predominant bacteria found in the airways of people with cystic fibrosis (pwCF), significantly contributing to lung disease progression. While various factors influencing the initial acquisition (IA) of these pathogens are known, …

fr, re (code pays fourni par la source)

At-admission prediction of mortality and pulmonary embolism in an international cohort of hospitalised patients with COVID-19 using statistical and machine learning methods

Munib Mesinovic, Xin Ci Wong, Giri Shan Rajahram, Barbara Wanjiru Citarella et autres

By September 2022, more than 600 million cases of SARS-CoV-2 infection have been reported globally, resulting in over 6.5 million deaths. COVID-19 mortality risk estimators are often, however, developed with small unrepresentative samples and with methodological limitations. It is highly important to …

gb, kr, my, nl, sa, jp, fr, be, us, de, it, pt, ie, th, qa, kw, es, gi, ca, br, bd, cl, Afrique du Sud, la (code pays fourni par la source)

Characteristics and outcomes of COVID-19 patients admitted to hospital with and without respiratory symptoms

Barbara Wanjiru Citarella, Elsa D. Ibáñez-Prada, Bronner P. Gonçalves, Martina Escher et autres

Background: COVID-19 is primarily known as a respiratory illness; however, many patients present to hospital without respiratory symptoms. The association between non-respiratory presentations of COVID-19 and outcomes remains unclear. We investigated risk factors and clinical outcomes in patients with no respiratory symptoms …

in, gb, co, lu, ca, nl, pt, ie, jp, id, es, fr, au (code pays fourni par la source)

Successful lung transplantation in genetic methionyl-tRNA synthetase–related alveolar proteinosis/lung fibrosis without recurrence under methionine supplementation: Medium-term outcome in 4 cases

Charlotte Roy, Nathalie Allou, Aurore Coulomb, Dominique Grenet et autres

Pulmonary alveolar proteinosis (PAP) results from the accumulation of lipoproteinaceous material in the alveoli and alveolar macrophages, and can be associated with pulmonary fibrosis, with a need for lung transplantation (LTx). Causes of PAP are autoimmune (90%-95%), secondary (5%), or hereditary (<1%). …

fr, re, us (code pays fourni par la source)

Sex differences in post-acute neurological sequelae of SARS-CoV-2 and symptom resolution in adults after coronavirus disease 2019 hospitalization: an international multi-centre prospective observational study

Sung‐Min Cho, Lavienraj Premraj, Denise Battaglini, Jonathon P. Fanning et autres

Although it is known that coronavirus disease 2019 can present with a range of neurological manifestations and in-hospital complications, sparse data exist on whether these initial neurological symptoms of coronavirus disease 2019 are closely associated with post-acute neurological sequelae of SARS-CoV-2 (severe …

us, au, es, it, gb, kh, Afrique du Sud (code pays fourni par la source)

High Prevalence and Incidence of Systemic Sclerosis in Reunion Island, a French Multi-Ethnical and Tropical Territory

A. Dubernet, Céline Roussin, Nathalie Sultan-Bichat, Aurélie Foucher et autres

re (code pays fourni par la source)

Implementation of Recommendations on the Use of Corticosteroids in Severe COVID-19

Félix Camirand-Lemyre, Laura Merson, Bharath Kumar Tirupakuzhi Vijayaraghavan, Aidan Burrell et autres

Importance: Research diversity and representativeness are paramount in building trust, generating valid biomedical knowledge, and possibly in implementing clinical guidelines. Objectives: To compare variations over time and across World Health Organization (WHO) geographic regions of corticosteroid use for treatment of severe COVID-19; …

ca, gb, in, au, Gambie, nl, jp, ie, ro, no (code pays fourni par la source)