Accès ouvert
2024
article
OpenAlex
Jinqiu Guan, Mengzhen Li, Yi Wang, Yu Zhang et autres
Abstract MYCN amplification is an independent poor prognostic factor in patients with high-risk neuroblastoma (NB). Further exploring the molecular regulatory mechanisms in MYCN-amplified NB will help to develop novel therapy targets. In this study, methylenetetrahydrofolate dehydrogenase 1 (MTHFD1) was identified as the …
cn
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2022
article
OpenAlex
Jinqiu Guan, Feifei Sun, Juan Wang, Junting Huang et autres
cn
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2021
article
OpenAlex
Xiaoqin Zhu, Wei Li, Jia Zhu, Huimou Chen et autres
This study evaluated the influence of MTHFR C677T/A1298C polymorphisms on the survival of pediatric NHL. We enrolled 374 patients including 283 males and 91 females between 2014 and 2020. The median age was 9 years. The tumor types included Burkitt lymphoma (n …
cn
(code pays fourni par la source)
2021
article
OpenAlex
Yingxia Lan, Jinqiu Guan, Jia Zhu, Juan Wang et autres
cn
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Accès ouvert
2021
article
OpenAlex
Huimou Chen, Suying Lü, Jinqiu Guan, Xiaoqin Zhu et autres
BACKGROUND: Malignant rhabdoid tumor of the kidney (RTK) is a rare and highly aggressive pediatric malignancy. Immune system dysfunction is significantly correlated with tumor initiation and progression. METHODS: We integrated and analyzed the expression profiles of immune-related genes (IRGs) in 65 RTK …
cn
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Accès ouvert
2020
preprint
OpenAlex
Xiaoqin Zhu, Wei Li, Jia Zhu, Huimou Chen et autres
Objective: We investigated the influence of methylenetetrahydrofolate reductase (MTHFR) C677T/A1298C polymorphisms on the survival of pediatric non-Hodgkin lymphoma (NHL) cases in south China treated with the modified Berlin-Frankfurt-Münster 95 protocol. Methods: We reviewed the medical records of 374 patients newly diagnosed at …
cn
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