Marco Endrizzi

Directional X‐Ray Scattering and Microtomography for Laboratory‐Based Imaging of Fibrous Materials and Biological Tissues

Carlos Navarrete-León, Alvaro Jose Gonzalez-Grajales, Harry Allan, Adam Doherty et autres

X‐ray microtomography enables nondestructive three‐dimensional imaging, yet conventional attenuation contrast provides limited sensitivity to microstructural organization below the system's spatial resolution. Dark‐field imaging addresses this limitation by detecting scattering from unresolved structures, enabling indirect access to sub‐resolution features across large fields of …

gb (code pays fourni par la source)

Universal Phase Contrast in Micro-CT Systems

Grammatiki Lioliou, Alberto Astolfo, Marco Endrizzi, David Bate et autres

Conventional high-resolution micro-CT systems are regarded as attenuation-based unless visible Fresnel fringes reveal the presence of propagation-based phase contrast. Here we show that this interpretation is incomplete. When propagation-induced phase transfer is non-negligible relative to the system blur, micro-CT operates in a …

Universal Phase Contrast in Micro-CT Systems

Grammatiki Lioliou, Alberto Astolfo, Marco Endrizzi, David Bate et autres

Conventional high-resolution micro-CT systems are regarded as attenuation-based unless visible Fresnel fringes reveal the presence of propagation-based phase contrast. Here we show that this interpretation is incomplete. When propagation-induced phase transfer is non-negligible relative to the system blur, micro-CT operates in a …

gb, us (code pays fourni par la source)

Material identification using laboratory X-ray beam tracking: quantitativeness and signal-to-noise ratio requirements

Sumera Rehman, Ashkan Ajeer, Connor Darling, Marco Endrizzi et autres

Simultaneous structural and elemental characterisation of a specimen in a non-destructive manner is an instrumental approach with applications in a variety of fields including energy materials, cultural heritage and life sciences. This is routinely performed at synchrotron facilities, e.g. by combining X-ray …

Material identification using laboratory X-ray beam tracking: quantitativeness and signal-to-noise ratio requirements

Sumera Rehman, Ashkan Ajeer, Connor Darling, Marco Endrizzi et autres

Simultaneous structural and elemental characterisation of a specimen in a non-destructive manner is an instrumental approach with applications in a variety of fields including energy materials, cultural heritage and life sciences. This is routinely performed at synchrotron facilities, e.g. by combining X-ray …

gb (code pays fourni par la source)

An imaging framework for nuclei-based three-dimensional cell quantification in intact tissue using phase-contrast X-ray CT

Tom Partridge, Reem Ahmad, Alberto Astolfo, Ian Buchanan et autres

Objective Quantitative analysis of cellular morphology and spatial organisation within intact tissue remains challenging, particularly when three-dimensional information must be preserved. This study investigates whether laboratory propagation-based phase-contrast X-ray computed tomography (CT) can support nuclei-based quantitative analysis in unstained tissue while retaining …

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Spatial resolution of X-ray beam-tracking microscopy

Harry Allan, Carlos Navarrete-León, Adam Doherty, Shashidhara Marathe et autres

X-ray beam-tracking is a phase-contrast imaging technique capable of simultaneously retrieving transmission, phase, and dark-field images. Although the spatial resolution in beam-tracking is largely considered to be 'aperture driven', no model yet exists to describe this in full. The dark-field channel is …

Spatial resolution of X-ray beam-tracking microscopy

Harry Allan, Carlos Navarrete-León, Adam Doherty, Shashidhara Marathe et autres

X-ray beam-tracking is a phase-contrast imaging technique capable of simultaneously retrieving transmission, phase, and dark-field images. Although the spatial resolution in beam-tracking is largely considered to be 'aperture driven', no model yet exists to describe this in full. The dark-field channel is …

gb (code pays fourni par la source)

X-ray radiography

Marco Endrizzi, Thomas P. Millard, Alessandro Olivo

Medical imaging as a scientific discipline began with the discovery of x-rays in 1895, and x-ray radiology quickly became the cornerstone of clinical diagnostic imaging. This chapter describes the physical processes involved in the generation of x-rays and the basic characteristics and …

Three-dimensional high-content imaging of unstained soft tissue with subcellular resolution using a laboratory-based X-ray microscope

Michela Esposito, Alberto Astolfo, Yang Zhou, Ian Buchanan et autres

With increasing interest in studying biological systems across spatial scales-from centimeters down to nanometers-histology continues to be the gold standard for tissue imaging at cellular resolution, providing an essential bridge between macroscopic and nanoscopic analysis. However, its inherently destructive and two-dimensional nature …

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Three-dimensional high-content imaging of unstained soft tissue with subcellular resolution using a laboratory-based X-ray microscope

Michela Esposito, Alberto Astolfo, Yang Zhou, Ian Buchanan et autres

Three-dimensional analysis of biological tissue is crucial for linking tissue morphology to cellular function. While conventional histology remains the gold standard for visualising tissue architecture at subcellular resolution, it is limited by its destructive, two-dimensional nature and anisotropic resolution, hindering its use …

gb (code pays fourni par la source)

Three-dimensional high-content imaging of unstained soft tissue with subcellular resolution using a laboratory-based X-ray microscope

Michela Esposito, Alberto Astolfo, Yang Zhou, Ian Buchanan et autres

Three-dimensional analysis of biological tissue is crucial for linking tissue morphology to cellular function. While conventional histology remains the gold standard for visualising tissue architecture at subcellular resolution, it is limited by its destructive, two-dimensional nature and anisotropic resolution, hindering its use …

gb (code pays fourni par la source)