Accès ouvert
2025
article
OpenAlex
Jie Yang, Bryan Sibert, Daniel Parrell, Eric Montemayor et autres
Cryo-electron tomography (cryo-ET) has emerged as a leading technique for visualizing large, transient, dynamic, and heterogenous macromolecules in their native or near-native states. From three-dimensional reconstructions (e.g., tomograms) of these complex systems, abundant molecules can be further analyzed for high-resolution structural information …
us, ie, il
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Saeed Roschdi, Eric Montemayor, Rahul Vivek, C.A. Bingman et autres
Poly(UG) or 'pUG' dinucleotide repeats are highly abundant sequences in eukaryotic RNAs. In Caenorhabditis elegans, pUGs are added to RNA 3' ends to direct gene silencing within Mutator foci, a germ granule condensate. Here, we show that pUG RNAs efficiently self-assemble into …
us
(code pays fourni par la source)
Accès ouvert
2023
article
OpenAlex
Juan C Sanchez, Eric Montemayor, Nicoleta Ploscariu, Daniel Parrell et autres
The bacterial flagellum is a complex, multi-protein structure consisting of a basal body, motor, hook, and filament [1]. The filament acts as an Archimedes’ screw propelling the cell body forward and is comprised of thousands of monomers called flagellins [2]. Flagellum biogenesis …
us
(code pays fourni par la source)
Accès ouvert
2023
preprint
OpenAlex
Juan C Sanchez, Eric Montemayor, Nicoleta Ploscariu, Daniel Parrell et autres
Abstract Flagella are dynamic, ion-powered machines with assembly pathways that are optimized for efficient flagella production. In bacteria, dozens of genes are coordinated at specific times in the cell lifecycle to generate each component of the flagellum. This is the case for …
us
(code pays fourni par la source)
Accès ouvert
2022
article
OpenAlex
Xingyang Fu, Harpreet Kaur, Margaret L. Rodgers, Eric Montemayor et autres
Spliceosome activation is the process of creating the catalytic site for RNA splicing and occurs de novo on each intron following spliceosome assembly. Dozens of factors bind to or are released from the activating spliceosome including the Lsm2-8 heteroheptameric ring that binds …
us
(code pays fourni par la source)
Accès ouvert
2022
article
OpenAlex
Xingyang Fu, Harpreet Kaur, Margaret L. Rodgers, Eric Montemayor et autres
Spliceosome activation is the process of creating the catalytic site for RNA splicing and occurs de novo on each intron following spliceosome assembly. Dozens of factors bind to or are released from the activating spliceosome including the Lsm2-8 heteroheptameric ring that binds …
Accès ouvert
2022
article
OpenAlex
Saeed Roschdi, Jenny Yan, Yuichiro Nomura, Cristian A. Escobar et autres
us
(code pays fourni par la source)
Accès ouvert
2022
preprint
OpenAlex
Xingyang Fu, Harpreet Kaur, Margaret L. Rodgers, Eric Montemayor et autres
Summary Spliceosome activation is the process of creating the catalytic site for RNA splicing and occurs de novo on each intron following spliceosome assembly. Dozens of factors bind to or are released from the activating spliceosome including the Lsm2-8 heteroheptameric ring that …
us
(code pays fourni par la source)
Accès ouvert
2021
preprint
OpenAlex
Saeed Roschdi, Jenny Yan, Yuichiro Nomura, Cristian A. Escobar et autres
The addition of poly(UG) ("pUG") repeats to 3' termini of mRNAs drives gene silencing and trans-generational epigenetic inheritance in the metazoan C. elegans. pUG tails promote silencing by recruiting an RNA-dependent RNA Polymerase (RdRP) that synthesizes small interfering (si)RNAs. Here we show …
us
(code pays fourni par la source)
Accès ouvert
2021
dataset
OpenAlex
Nancy Meyer, Elizabeth Wright, Jie Yang, Nicoleta Ploscariu et autres
us
(code pays fourni par la source)
Accès ouvert
2021
dataset
OpenAlex
Nancy Meyer, Elizabeth Wright, Jie Yang, Nicoleta Ploscariu et autres
us
(code pays fourni par la source)
Accès ouvert
2021
dataset
OpenAlex
Nancy Meyer, Elizabeth Wright, Jie Yang, Nicoleta Ploscariu et autres
us
(code pays fourni par la source)