Marie‐Hélène Perez

Analgesia, sedation, and mobilization practices in pediatric patients supported with extracorporeal membrane oxygenation across Europe: an ESPNIC survey

Francesca Cavagnero, Aparna Hoskote, Jon Lillie, Luc Morin et autres

it, gb, fr, de, es, nl, be, hu, ch, tr, us (code pays fourni par la source)

French translation, cultural and digital adaptation of the state behavioral scale for sedation assessment in paediatric intensive care

Silvia Alvarado, Anne‐Sylvie Ramelet, Gwenaëlle De Clifford‐Faugère, Guillaume Maître et autres

INTRODUCTION: Children admitted to paediatric intensive care units frequently require invasive interventions and mechanical ventilation, requiring meticulous sedation management. Optimal care depends on careful titration of analgesics and sedatives, guided by clinician-administered assessment instruments to ensure proper dosing and minimise adverse effects. …

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The OCTO ‐Plus Intervention to Support Families of Chronically Critically Ill Children in Paediatric Critical Care: A Pilot Study

Mark Marston, Marie‐Hélène Perez, Anne‐Sylvie Ramelet

BACKGROUND: Families of chronically critically ill (CCI) children admitted to paediatric critical care (PCC) experience significant and long-lasting psychological distress. Structured family-centred care consultations, using a family system approach, have shown promise in mitigating these effects. Though most studies in PCC are …

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Population Pharmacokinetics of Levosimendan and its Metabolites OR-1855 and OR-1896 in Critically Ill Adults, Neonates and Infants on Veno-Arterial ECMO

Stéphane Bertin, Monia Guidi, David Haefliger, Paul Thoueille et autres

BACKGROUND AND OBJECTIVE: Levosimendan is an inotrope and vasodilator agent commonly used in critical care, particularly to facilitate weaning from veno-arterial extracorporeal membrane oxygenation (VA-ECMO). However, critical illness and ECMO may affect levosimendan and its clinically relevant metabolites' pharmacokinetics, potentially compromising circulating …

ch, us (code pays fourni par la source)

Effects of Extracorporeal Membrane Oxygenation Circuits on Drug Sequestration: A Review of Ex Vivo Experiments

Stéphane Bertin, David Haefliger, Antoine Schneider, Raphaël Giraud et autres

Background: Extracorporeal membrane oxygenation (ECMO) can affect the disposition of drugs, notably by sequestering them in a circuit. This review aimed to provide a comprehensive summary of existing ex vivo studies investigating the impact of contemporary ECMO circuits on drug sequestration, and …

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Positive communication for decreasing burnout in intensive-care-unit staff: a cluster-randomized trial

Élie Azoulay, Sheila Nainan Myatra, Gabriel Heras La Calle, Samir Jaber et autres

fr, us, be, in, es, bd, gb, tr, gr, pt, sa, il, uy, kw, it (code pays fourni par la source)

Early detection of clinical deterioration in a pediatric intermediate care unit: a best practice implementation project

Céline Lomme, Chantal Grandjean, Vivianne Chanez, Marie‐Hélène Perez

BACKGROUND: The Pediatric Intermediate Care Unit (Ped-IMC) provides specialized monitoring and care for children at high risk of clinical deterioration. The Pediatric Early Warning Score (PEWS) assesses key factors, such as vital signs and concerns from parents and nursing staff. The score …

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Successful EXCOR biventricular assist device weaning because of recovery in a child

Morgane Chave, Amir‐Reza Hosseinpour, Fabrizio De Rita, Sylvain Mauron et autres

IntroductionVentricular assist devices (VADs) are used in children usually as a bridge to transplantation and occasionally also as a bridge to recovery, e.g., for acute myocarditis. However, in cases of recovery, weaning criteria are not well defined and protocols are scarce.Case reportWe …

ch, gb, de (code pays fourni par la source)

Impact of a Nutrition Protocol on Vitamin D Supplementation in a Pediatric Intensive Care Unit: A Retrospective Cohort Study

Guillaume Maître, Laurence Boillat, Frida Rizzati, Pauline Lauwers et autres

BACKGROUND: Vitamin D deficiency (VDD) is highly prevalent in pediatric critically ill patients and is a potentially modifiable risk factor during critical illness. There are no established national or international recommendations for vitamin D supplementation in Pediatric Intensive Care Unit (PICU) patients. …

ch (code pays fourni par la source)

Validity and repeatability of the pulp/tooth area ratio for age estimation in adults: A test of the Cameriere et al. methods in a U.S. population

Alexandra Semma Tamayo, Marie‐Hélène Perez, Kailee Behunin, Nolan M Robinson et autres

us (code pays fourni par la source)

Piperacillin dosing in pediatric patients and augmented renal clearance: are current guidelines sufficient to achieve therapeutic concentration coverage?

Anne Ravix, Ermindo R. Di Paolo, Kim Dao, Marie‐Hélène Perez et autres

BACKGROUND: Appropriate dosing of piperacillin/tazobactam is crucial for hospitalized children and might be a challenge in case of augmented renal clearance. This study assessed the appropriateness of piperacillin dosing regimens recommended to attain pharmacokinetic/pharmacodynamic targets by pediatric guidelines using a population pharmacokinetic …

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Pain, Agitation, Delirium, and Iatrogenic Withdrawal Syndrome Management in Children Who Are Critically Ill: Protocol for a European Clinical Practice Guideline Using the Grading of Recommendations Assessment, Development, and Evaluation Approach

Ibo MacDonald, Alexia Trombert, Cécile Jaques, Gwenaëlle De Clifford‐Faugère et autres

BACKGROUND: In pediatric intensive care units, pain, sedation, delirium, and iatrogenic withdrawal syndrome (IWS) must be managed as interrelated conditions. Although clinical practice guidelines (CPGs) exist, new evidence needs to be incorporated, gaps in recommendations addressed, and recommendations adapted to the European …

ch, be, nl, ua, de, it, gb, fr, is, hu, es, ee, au, pl, us, tr (code pays fourni par la source)