Meghan E. Turnis

Anti-apoptotic MCL-1 promotes long-chain fatty acid oxidation through interaction with ACSL1

Tristen Wright, Meghan E. Turnis, Christy R. Grace, Xiao Li et autres

us (code pays fourni par la source)

Genetic ablation of Immt induces a lethal disruption of the MICOS complex

Stephanie Rockfield, Meghan E. Turnis, Ricardo Rodriguez-Enriquez, Madhavi Bathina et autres

The mitochondrial contact site and cristae organizing system (MICOS) is important for crista junction formation and for maintaining inner mitochondrial membrane architecture. A key component of the MICOS complex is MIC60, which has been well studied in yeast and cell culture models. …

us (code pays fourni par la source)

Inducible genetic ablation of Immt induces a lethal disruption of the MICOS complex

Stephanie Rockfield, Meghan E. Turnis, Ricardo Rodriguez-Enriquez, Madhavi Bathina et autres

Abstract The mitochondrial contact site and cristae organizing system (MICOS) is important for cristae junctions (CJ) formation and for maintaining inner mitochondrial membrane (IMM) architecture. As the largest member, MIC60 is the primary scaffold protein for this complex. While MIC60 has been …

us (code pays fourni par la source)

Supplementary Data S3 from The Heme-Regulated Inhibitor Pathway Modulates Susceptibility of Poor Prognosis B-Lineage Acute Leukemia to BH3-Mimetics

Kaitlyn H. Smith, Amit Budhraja, John William Lynch, Kathryn G. Roberts et autres

Synergy analysis of DHA and BH3-mimetics in BCR-ABL+ B-ALL cells

Supplementary Data S8 from The Heme-Regulated Inhibitor Pathway Modulates Susceptibility of Poor Prognosis B-Lineage Acute Leukemia to BH3-Mimetics

Kaitlyn H. Smith, Amit Budhraja, John William Lynch, Kathryn G. Roberts et autres

Densitometry for immunoblots

Supplementary Tables from The Heme-Regulated Inhibitor Pathway Modulates Susceptibility of Poor Prognosis B-Lineage Acute Leukemia to BH3-Mimetics

Kaitlyn H. Smith, Amit Budhraja, John William Lynch, Kathryn G. Roberts et autres

sgRNA sequences for knockout cell lines and Synergy analysis of combinatorial drug treatments, determined by response surface modeling.

Supplementary Data S7 from The Heme-Regulated Inhibitor Pathway Modulates Susceptibility of Poor Prognosis B-Lineage Acute Leukemia to BH3-Mimetics

Kaitlyn H. Smith, Amit Budhraja, John William Lynch, Kathryn G. Roberts et autres

Synergy analysis of HRI activation ex vivo

Supplementary Data S5 from The Heme-Regulated Inhibitor Pathway Modulates Susceptibility of Poor Prognosis B-Lineage Acute Leukemia to BH3-Mimetics

Kaitlyn H. Smith, Amit Budhraja, John William Lynch, Kathryn G. Roberts et autres

HRI activation synergizes with BH3-mimetics in Ph+ and Ph-like ALL cell lines

Supplementary Data S2 from The Heme-Regulated Inhibitor Pathway Modulates Susceptibility of Poor Prognosis B-Lineage Acute Leukemia to BH3-Mimetics

Kaitlyn H. Smith, Amit Budhraja, John William Lynch, Kathryn G. Roberts et autres

Activation of integrated stress response by DHA or succinylacetone

Supplementary Data S6 from The Heme-Regulated Inhibitor Pathway Modulates Susceptibility of Poor Prognosis B-Lineage Acute Leukemia to BH3-Mimetics

Kaitlyn H. Smith, Amit Budhraja, John William Lynch, Kathryn G. Roberts et autres

Synergy analysis of DHA or BTdPCU combined with BH3-mimetics in PDX cells

Supplementary Data S1 from The Heme-Regulated Inhibitor Pathway Modulates Susceptibility of Poor Prognosis B-Lineage Acute Leukemia to BH3-Mimetics

Kaitlyn H. Smith, Amit Budhraja, John William Lynch, Kathryn G. Roberts et autres

Stress pathways in cellular response to DHA

Supplementary Data S4 from The Heme-Regulated Inhibitor Pathway Modulates Susceptibility of Poor Prognosis B-Lineage Acute Leukemia to BH3-Mimetics

Kaitlyn H. Smith, Amit Budhraja, John William Lynch, Kathryn G. Roberts et autres

Synergy analysis of BTdCPU and BH3-mimetics in BCR-ABL+ B-ALL cells