Accès ouvert
2026
preprint
OpenAlex
Matthew A. Romero, Peggie Chien, Chiara Nicoletti, Hanna L Liliom et autres
Abstract Developmental gene expression is under tight temporal and spatial control. This regulation is imparted by tissue specific enhancers that integrate developmental signals into transcriptional responses to allow for developmental progression. Often species specific, the enhancers that regulate human muscle progenitor and …
us, qa
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Dieu-Huong Hoang, Jessica Bouvière, Johanna Galvis, Pauline Moullé et autres
Muscle regeneration is impaired with aging, due to both intrinsic defects of muscle stem cells (MuSCs) and alterations of their niche. Here, we monitor the cells constituting the MuSC niche over time in young and old regenerating mouse muscle. Aging alters the …
fr, ch
(code pays fourni par la source)
Accès ouvert
2024
preprint
OpenAlex
Dieu-Huong Hoang, Jessica Bouvière, Johanna Galvis, Pauline Moullé et autres
Abstract Muscle regeneration is impaired in the aged organism, due to both intrinsic defects of muscle stem cells (MuSCs) and alterations of their environmental niche. However, the latter has still been poorly explored. Here, we compared and analyzed the time course of …
fr, ca, gb
(code pays fourni par la source)
Accès ouvert
2021
article
OpenAlex
Simona Feno, Fabio Munari, Denis Vecellio Reane, Rosanna Gissi et autres
Damaged skeletal muscle can regenerate because of the coordinated action of immune cells with muscle stem cells, called satellite cells. Proinflammatory macrophages infiltrate skeletal muscle soon after injury to sustain the proliferation of satellite cells. These macrophages later acquire the anti-inflammatory phenotype …
it, fr
(code pays fourni par la source)
Accès ouvert
2019
article
OpenAlex
Jessica Bouvière, Aurélie Trignol, Dieu-Huong Hoang, Peggy del Carmine et autres
Although skeletal muscle is capable of complete recovery after an injury, specific situations require support or acceleration of this process, such as in the elderly and athletes, respectively. Skeletal muscle regeneration is due to muscle stem cells (MuSCs) that undergo adult myogenesis, …
fr
(code pays fourni par la source)