Ciliogenesis associated kinase 1 accumulates in its inactive form during polycystic kidney disease progression
Alice S. Serafin, Charlène Coquil, Aurore Dupuy, Mattias Lindberg et autres
Abstract Ciliogenesis associated kinase 1 (CILK1) deficiency in human and mice results in kidney developmental defects including cystogenesis. However, the biology of CILK1 in autosomal dominant polycystic kidney disease (ADPKD), the most common inherited kidney disease, remains to be investigated. Here, we …
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