Zhen Dou

MAD2B guides chromosome stability in mitosis via the MAD2B–CIP2A signaling axis

Umer Ejaz, Fangyuan Xiong, Hengyi Shao, Tahir Ullah et autres

Error-free mitosis depends on accurate chromosome attachment to spindle microtubules, monitored by the spindle assembly checkpoint machinery, which prevents precocious chromosome segregation and reduces the risk of aneuploidy. MAD2B, a homologue of MAD2, is critical for mitotic quality control and DNA damage …

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Probing Centromere Plasticity and Chromatin Remodeling Using Single‐Molecule Techniques

R X Liu, Jin Zhao, Hongfei Ma, Wenping Hu et autres

The centromere functions as an essential interactive hub for mediating the equal distribution of sister chromatids during eukaryotic cell division and is subject to cell cycle-specific plasticity regulation. To ensure the replication, transcription, and repair of genetic information, chromatin remodeling is an …

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Effect of electro-acupuncture on postpartum urinary retention: a protocol for multicenter, randomized and placebo-controlled trial

Zhen Dou, Yunzhi Zhang, Hongyan Cui, Xiaoli Zhao et autres

Background: Postpartum urinary retention (PUR) is a common and clinically relevant complication after delivery. Although urinary catheterization can provide temporary relief from voiding disorders, it is associated with discomfort, pain, potential urethral trauma, and an increased risk of urinary tract infection. Preliminary …

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Mechanical properties and microstructure of B4C–ZrB2–graphite composites fabricated by reactive spark plasma sintering

Liangliang Liu, Zhen Dou, Songlin Ran

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Dynamic crotonylation of Bub3 regulates mitotic checkpoint silencing and chromosome segregation

Xingchen Yu, Wenwen Wang, Fangyuan Xiong, Xiao Ni Yuan et autres

Xufan Shi, Xingchen Yu, Wenwen Wang, Fangyuan Xiong, Xiao Yuan, Qing Hu, Xiaoyu Song, Zhen Dou, Xuebiao Yao, Liangyu Zhang; Dynamic crotonylation of Bub3 r

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Modelling TIP60–YAP signalling in epithelial cell renewal using 3D gastric organoids

Hazrat Ismail, Zhen Dou, Dongmei Wang, Hengyi Shao et autres

Hazrat Ismail, Zhen Dou, Dongmei Wang, Hengyi Shao, Xinjiao Gao, Chao Xu, Xing Liu, Chuanhai Fu, Xuebiao Yao, Xiaoyu Song; Modelling TIP60–YAP signalling i

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Research on twin crystal structure evolution and properties of copper-tin diamond ultra-thin grinding wheel for silicon wafer cutting

Zhen Dou, Yuanru Feng, Xiaodi Li, Liuning Liang et autres

Phosphorylation of Lamin A/C regulates the structural integrity of the nuclear envelope

Shuaiyu Liu, Fangyuan Xiong, Zhen Dou, Lingluo Chu et autres

Dynamic disassembly and reconstruction of the nuclear lamina during entry and exit of mitosis, respectively, are pivotal steps in the proliferation of higher eukaryotic cells. Although numerous post-translational modifications of lamin proteins have been identified, key factors driving the nuclear lamina dynamics …

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Semi-Preparation and X-ray Single-Crystal Structures of Sophocarpine-Based Isoxazoline Derivatives and Their Pesticidal Effects and Toxicology Study

Jianwei Xu, Zhen Dou, Min Lv, Yanyan Wang et autres

Recently, research and development of novel pesticides from natural plant products have received much attention. To accelerate the application of sophocarpine as the agrochemical candidate, a series of novel sophocarpine-based isoxazoline derivatives were prepared by the 1,3-dipolar [2 + 3] cycloaddition reaction …

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Comparative Study on the SRAMs Based on III-V Homojunction and Heterojunction TFETs

Yunhe Guan, Jiachen Lu, Zhen Dou, Weihan Sun et autres

Although Tunnel Field-Effect Transistors (TFETs) are acknowledged for energy-efficient devices, their low on-state current significantly constrains their development. In contrast to conventional TFETs, III-V heterojunction TFETs demonstrate steeper switching characteristics and higher on-state currents. This paper employs a semi-empirical Verilog-A compact model …

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Effect of electro-acupuncture on postpartum urinary retention —— A protocol for multicenter, randomized and placebo-controlled trial

Zhen Dou, Yunzhi Zhang, Hongyan Cui, Xiaoli Zhao et autres

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Kai Yu Zhong Yu recipe mitigates stress-induced accelerated follicle loss in mice by regulating the interplay between apoptosis and autophagy via the SIRT1/FOXO1/3 pathway

Xiaoli Zhao, Beilei Rong, Zhen Dou, Rong Dong et autres

Background: Psychological stress-related infertility is often attributed to a decline in both the quality and quantity of oocytes. Kai Yu Zhong Yu (KYZY) recipe, a classic herbal formula in Traditional Chinese Medicine (TCM), has been employed for centuries to address stress-related infertility. …