Lili He

A two-stage deep learning pipeline for automated detection and localization of endotracheal tubes on pediatric chest radiographs: a pilot study

Hailong Li, Bohan Zhang, Elanchezhian Somasundaram, Mahdieh Shabanian et autres

BACKGROUND: Endotracheal tubes (ETTs) are critical life-support devices for mechanically ventilated pediatric patients, yet automated ETT assessment on pediatric chest radiographs (CXRs) remains limited. OBJECTIVE: To develop and evaluate a two-stage deep learning pipeline for automated detection and localization of ETTs on …

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First Total Synthesis of N 1 ‐Dihydrocaffeoyl ‐ N 10 ‐Caffeoyl Spermidine and (±) ‐ Lycium Spermidine A

Lili He, Lijuan Zhai, Jingwen Ji, Yuanyu Gao et autres

ABSTRACT Spermidine alkaloids are naturally occurring polyamines widely found in medicinal plants of the Solanaceae family. They have been extensively studied for their neuroprotective and anti‐inflammatory properties. Herein, we report the first total synthesis of N 1 ‐dihydrocaffeoyl‐ N 10 ‐caffeoyl spermidine …

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An Improved Total Synthesis of Kukoamine B Dihydrobromide

Lijuan Zhai, Lili He, Jingwen Ji, Yuanyu Gao et autres

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Canagliflozin ameliorates high-salt-induced renal injury and premature aging in male Dahl salt-sensitive rats, with associated changes in SIRT6/HIF-1α signaling

Qiuyan Wang, Yi Liang, Qingjuan Zuo, Lili He et autres

Sodium-glucose cotransporter 2 inhibitors (SGLT2is) exhibit renoprotective effects in diabetic and nondiabetic patients; however, the underlying mechanism remains unclear. This study aimed to investigate the effects of canagliflozin (an SGLT2i) on salt-sensitive hypertensive kidneys. Male Dahl salt-sensitive rats were fed a high-salt …

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Establishment and validation of a risk prediction model for urinary tract infection in elderly patients with type 2 diabetes mellitus

Yaqiang Li, Lin Li, Lili He

Objectives This study aimed to identify the risk factors for urinary tract infection (UTI) in elderly patients with type 2 diabetes mellitus (T2DM) and to develop and validate a nomogram that predicts the probability of UTI based on these factors. Methods We …

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0849 The mechanotransducer piezo1 coordinates metabolism and inflammation to promote skin regeneration

Yingchao Xue, Elizabeth Winnicki, Z. Zhang, I. Lopez et autres

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Canagliflozin improves high-salt-induced aortic arteriosclerosis and premature aging in dahl salt-sensitive rats through the SIRT6/HIF-1 α signaling pathway

Qiuyan Wang, Yi Liang, Qingjuan Zuo, Lili He et autres

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Metabolomic Analysis of the Effects of Canagliflozin on HFpEF Rats and Its Underlying Mechanism

Qingjuan Zuo, Sai Ma, Lili He, Zhongli Wang et autres

BACKGROUND: Heart failure with preserved ejection fraction (HFpEF) represents a challenging cardiovascular condition characterized by normal systolic function but impaired diastolic performance. Despite its increasing prevalence, therapeutic options remain limited. This study investigated the metabolic effects of canagliflozin, a sodium-glucose cotransporter 2 …

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Canagliflozin ameliorates ferritinophagy in HFpEF rats

Sai Ma, Qingjuan Zuo, Lili He, Guorui Zhang et autres

Background: Recent studies have shown that sodium-glucose cotransporters-2 (SGLT2) inhibitors significantly improve major adverse cardiovascular events in heart failure with preserved ejection fraction (HFpEF) patients, but the exact mechanism is unknown. Ferritinophagy is a special form of selective autophagy that participates in …

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First Total Synthesis of Lycium Spermidine a and N1-Dihydrocaffeoyl -N10-Caffeoyl Spermidine

Lili He, Lijuan Zhai, Jingwen Ji, Dong Tang et autres

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[Retracted] Tanshinone IIA regulates colorectal cancer apoptosis via attenuation of Parkin‑mediated mitophagy by suppressing AMPK/Skp2 pathways

Lili He, Lixin Guo

Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that certain of the immunofluorescence assay data shown in Fig. 4A on p. 1698 were strikingly similar to data that had already been submitted for …

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Synergistic solidification and mechanism research of electrolytic manganese residue and coal fly ash based on C-A-S-H gel material

Bo Liu, Bo Yue, Lili He, Bang-bang Meng et autres

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