Marco Verani

Transport of pathogens through saturated porous rocks with variable flow and salinity

Valentina Prigiobbe, Maria Clementina Caputo, Osvalda De Giglio, Antonella Francesca Savino et autres

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“Navigating Healthy Waters”: monitoring ship wastewater as a key defense against infectious diseases—a pilot study on a Mediterranean seaport

Ileana Federigi, Nunzio Zotti, Marzia Pellegrini, Marco Verani et autres

Wastewater-based surveillance represents a non-invasive approach to monitor pathogen circulation, but data on cruise ships are scarce, although this enclosed environment is prone to infectious diseases spreading. We conducted a pilot study in a Mediterranean seaport (Italy) between July and October 2024, …

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In Vitro Evaluation of Virucidal Effect of Polysaccharides Extracted and Purified from Arthrospira platensis and Dunaliella salina on Human Adenovirus Type 5 in A549 Cells

Marco Verani, Clementina Manera, Alessandra Pagani, Matteo Banti et autres

Polysaccharides derived from cyanobacteria and microalgae have attracted increasing interest as natural virucidal agents. Among them, polysaccharides from the cyanobacterium Arthrospira platensis (A. platensis), and the green microalgae Dunaliella salina (D. salina) have shown virucidal activities, mainly against enveloped viruses, while evidence …

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An Italian Study of PM0.5 Toxicity: In Vitro Investigation of Cytotoxicity, Oxidative Stress, Intercellular Communication, and Extracellular Matrix Metalloproteases

Nathalie Steimberg, Giovanna Mazzoleni, Jennifer Boniotti, Milena Villarini et autres

Particulate matter (PM), mainly PM0.5, represents a significant concern for human health, particularly relating to lung homeostasis, and more research is required to ascertain its tissue tropism and the molecular pathways involved. In this study, we first focus on classical in vitro …

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Evaluating Population Normalization Methods Using Chemical Data for Wastewater-Based Epidemiology: Insights from a Site-Specific Case Study

Marco Verani, Ileana Federigi, Alessandra Angori, Alessandra Pagani et autres

Wastewater-based epidemiology (WBE) has been widely employed to track the spread of human pathogens; however, correlating wastewater data with clinical surveillance remains challenging due to population variability and environmental factors affecting wastewater composition. This study evaluated different SARS-CoV-2 normalization methods, comparing static …

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Transport of pathogens in saturated porous rocks under variable flow and salinity

Alessandro Ghirotto, Valentina Prigiobbe, Maria Clementina Caputo, Osvalda De Giglio et autres

The transport of pathogens through rocks is often regarded as negligible unless there are fractures in the medium. However, sedimentary rocks may have a porosity that allows the migration of pathogens even when they are unfractured.In this work, we investigated the transport …

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Study Protocol of Predictive Dynamics of Microbiological Contamination of Groundwater in the Earth Critical Zone and Impact on Human Health (DY.MI.CR.ON Project)

Marco Verani, Osvalda De Giglio, Maria Clementina Caputo, Giorgio Cassiani et autres

Groundwater is one of the major sources of water supply for human needs. But anthropic activities such as agriculture are causing significant volume depletion and quality deterioration, favoring microbial contamination that has a negative impact on human health. The geological characteristics of …

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Evaluation of Trends in Influenza A and B Viruses in Wastewater and Human Surveillance Data: Insights from the 2022–2023 Season in Italy

Pamela Mancini, David Brandtner, Carolina Veneri, Giusy Bonanno Ferraro et autres

Wastewater-based epidemiology (WBE) is a recognized, dynamic approach to monitoring the transmission of pathogens in communities through urban wastewater. This study aimed to detect and quantify influenza A and B viruses in Italian wastewater during the 2022–2023 season (October 2022 to April …

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Wastewater-based surveillance of respiratory viruses in Northern Tuscany (Italy): Challenges and added value for public health purposes

Annalaura Carducci, Ileana Federigi, Alessandra Almeida Castro Pagani, Nebiyu Tariku Atomsa et autres

During the COVID-19 pandemic, wastewater-based surveillance (WBS) showed great potential as an early warning system and could complement human clinical surveillance. This study aimed to highlight the added value of WBS for respiratory infections alongside different clinical surveillance systems. Sewage collected at …

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A model learning framework for inferring the dynamics of transmission rate depending on exogenous variables for epidemic forecasts

Giovanni Ziarelli, Stefano Pagani, Nicola Parolini, Francesco Regazzoni et autres

In this work, we aim to formalize a novel scientific machine learning framework to reconstruct the hidden dynamics of the transmission rate, whose inaccurate extrapolation can significantly impair the quality of the epidemic forecasts, by incorporating the influence of exogenous variables (such …

Integrated environmental and clinical surveillance for the prevention of acute respiratory infections (ARIs) in indoor environments and vulnerable communities (Stell-ARI): Protocol

Annalaura Carducci, Guglielmo Arzilli, Nebiyu Tariku Atomsa, Giulia Lauretani et autres

The epidemiological relevance of viral acute respiratory infections (ARIs) has been dramatically highlighted by COVID-19. However, other viruses cannot be neglected, such as influenza virus, respiratory syncytial virus, human adenovirus. These viruses thrive in closed spaces, influenced by human and environmental factors. …

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A systematic scoping review of antibiotic-resistance in drinking tap water

Ileana Federigi, Silvia Bonetta, M. Tesauro, Osvalda De Giglio et autres

Environmental matrices have been considered of paramount importance in the spread of antibiotic-resistance; however, the role of drinking waters is still underexplored. Therefore, a scoping review was performed using a systematic approach based on PRISMA guidelines, with the aim of identifying and …

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