Giancarlo Acuto

Almotriptan 12.5 mg in menstrually related migraine: A randomized, double-blind, placebo-controlled study

Gianni Allais, Gennaro Bussone, Giovanni D’Andrea, Franca Moschiano et autres

BACKGROUND: Menstrually related migraine (MRM) affects more than half of female migraineurs. Because such migraines are often predictable, they provide a suitable target for treatment in the mild pain phase. The present study was designed to provide prospective data on the efficacy …

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Evolution of migraine-associated symptoms in menstrually related migraine following symptomatic treatment with almotriptan

Gianni Allais, Giancarlo Acuto, Chiara Benedetto, Giovanni D’Andrea et autres

In addition to headache, migraine is characterized by a series of symptoms that negatively affects the quality of life of patients. Generally, these are represented by nausea, vomiting, photophobia, phonophobia and osmophobia, with a cumulative percentage of the onset in about 90% …

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Naproxen sodium in short-term prophylaxis of pure menstrual migraine: pathophysiological and clinical considerations

Gianni Allais, Gennaro Bussone, Ilaria Castagnoli Gabellari, Marina Zonca et autres

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A pharmacoeconomic evaluation of oral triptans in the treatment of migraine in Italy.

Sadakatali Gori, Nicola Morelli, Giancarlo Acuto, F Caiola et autres

AIM: The goal of this economic evaluation was to compare the cost-efficacy of oral triptans currently used in the treatment of migraine in Italy. METHODS: The cost analysis of drugs was conducted through a structured decision tree, built up taking into account …

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Efficacy and tolerability of almotriptan versus zolmitriptan for the acute treatment of menstrual migraine

Gianni Allais, Giancarlo Acuto, Xavier Cabarrocas, Ramón Esbrí et autres

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Efficacy and tolerability of almotriptan versus zolmitriptan for the acute treatment of menstrual migraine MENSTRUAL MIGRAINE

Gianni Allais, Chiara Benedetto, Giancarlo Acuto, Xavier Cabarrocas et autres

Menstrual migraine (MM) attacks are a chal- lenge for the headache specialist, because they are partic- ularly difficult to treat. Almotriptan is a second-generation triptan successfully used for the acute treatment of migraine. No data on the efficacy and safety of almotriptan …

Nitric oxide-donating aspirins spare the gastrointestinal (GI) system and improve the treatment of inflammation-related GI and cardiovascular pathologies

Manlio Bolla, Giancarlo Acuto, Piero Del Soldato

For decades, aspirin has represented the elective treatment for inflammatory-based pathologies, due to its antipyretic and anti-inflammatory activities [1]. These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the …

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NCX-1000, a nitric oxide-releasing derivative of ursodeoxycholic acid, ameliorates portal hypertension and lowers norepinephrine-induced intrahepatic resistance in the isolated and perfused rat liver

Stefano Fiorucci, Elisabetta Antonelli, Vincenzo Brancaleone, Laura Sanpaolo et autres

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Somatostatin and its analog lanreotide inhibit the proliferation of dispersed human non-functioning pituitary adenoma cells in vitro

Tullio Florio, Stefano Thellung, Sara K. Arena, Alessandro Corsaro et autres

OBJECTIVE: Somatostatin is a powerful inhibitor of hormone secretion and cell proliferation. Treatment with somatostatin analogs in humans causes a reduction in size and secretory activity of some endocrine tumors, including somatotropic pituitary adenomas. Less studied are the effects of somatostatin agonists …

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Multicentre Double-Blind Clinical Trial of Iron Protein Succinylate in Comparison With Iron Sulfate in the Treatment of Iron Deficiency Anaemia

Yves Najean, Giancarlo Acuto, Aurelio Scotti

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A comparative study of free plasma choline levels following intramuscular administration of L-alpha-glycerylphosphorylcholine and citicoline in normal volunteers.

Giuliana Gatti, Nicoletta Barzaghi, Giancarlo Acuto, G. Abbiati et autres

L-alpha-glycerylphosphorylcholine (alpha-GPC) is a recently developed cognitive enhancer whose mode of action is considered to involve the release of free choline, which is then utilized for acetylcholine and phosphatidylcholine biosynthesis in the brain. The purpose of this study was to evaluate the …

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Blood binding of selezen (imidazole salicylate) in man.

Roland Zini, Didier Morin, Giancarlo Acuto, Carlo Bianchini et autres

The interactions of selezen (imidazole salicylate) with human blood components were studied by equilibrium dialysis. These interactions were limited to the binding of salicylate to human serum albumin (HSA). The binding was saturable and involved several classes of binding sites with different …

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