Monica Peravali

SurvivorCHIP: Evaluation of clonal hematopoiesis in women treated for breast cancer.

Reem Bahr, Chidera Nosiri, Gege Gui, Devdeep Mukherjee et autres

1082 Background: Clonal hematopoiesis (CH) has been associated with reduced overall survival and is shown to be increased in patients with solid tumors after receiving chemotherapy and radiotherapy. However, the clinical implications of these observations have not been prospectively evaluated among different …

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Impact of Baseline Clinical Biomarkers on Treatment Outcomes in Patients With Advanced NSCLC Receiving First-line Pembrolizumab-Based Therapy

Ishani Joshi, Monica Peravali, Xue Geng, Suman Rao et autres

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Improving Feedback for Hematology and Oncology Fellows Via Virtual Workshops: Sustainability Analysis

Sarah Sewaralthahab, Monica Peravali, Ilana Schlam, Gene Cunningham et autres

Abstract Background Effective feedback is an important tool in medical education for the learning and growth of trainees and for faculty development. It allows learners to remain on course in reaching competence in clinical, research, and interpersonal skills, yet the impact of …

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Abstract 372: Association between pre-treatment biomarkers and survival in metastatic non-small cell lung cancer patients treated with first-line pembrolizumab

Ishani Joshi, Monica Peravali, Xue Geng, Jiahua Zhang et autres

Abstract Background: The introduction of immune checkpoint inhibitors such as pembrolizumab has significantly improved the outcomes of patients with metastatic non-small cell lung cancer (NSCLC). Pre-treatment biomarkers and clinical parameters such as body mass index (BMI), neutrophil-lymphocyte ratio (NLR), albumin, and antibiotic …

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Improving feedback for hematologists and oncologists in training.

Ilana Schlam, Sarah Sewaralthahab, Monica Peravali, Calvin L. Chou et autres

11025 Background: Feedback is an integral part of the learning process, allowing learners to remain on course in reaching competence in clinical, research, and interpersonal skills. However, the impact of teaching feedback during hematology-oncology training has not been studied. We aimed to …

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Safety and Efficacy of First-Line Pembrolizumab in Black Patients with Metastatic Non-Small Cell Lung Cancer

Monica Peravali, Jaeil Ahn, Kevin Chen, Suman Rao et autres

INTRODUCTION: Pembrolizumab, an immune checkpoint inhibitor (ICI), has become an integral part of front-line treatment of metastatic non-small cell lung cancer (NSCLC). However, pivotal trials had significant underrepresentation of Black patients (pts). Lack of sufficient evidence regarding safety and efficacy of ICIs …

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P09.25 Role of Immune Checkpoint Inhibitors (ICPi) in KRAS-Mutated Non-Small Cell Lung Cancer (NSCLC)

Monica Peravali, Cristiane Gomes-Lima, Eshetu Tefera, Meredith A. Baker et autres

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Racial disparities in immune-related adverse events of immune checkpoint inhibitors and association with survival based on clinical and biochemical responses

Monica Peravali, Cristiane Gomes-Lima, Eshetu Tefera, Mairead Baker et autres

BACKGROUND: irAE) with thyroid dysfunction as a commonly reported abnormality. There is increasing evidence showing positive association with development of irAE and survival. However, prior trials with ICPi had underrepresentation of minorities with < 5% African Americans. AIM: To evaluate the association …

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A Systematic Review and Meta-Analysis of Clinical Characteristics and Outcomes in Patients With Lung Cancer with Coronavirus Disease 2019

Monica Peravali, Ishani Joshi, Jaeil Ahn, Chul Kim

Cancer is considered to be an independent risk factor for severe illness and higher mortality in patients with coronavirus disease 2019 (COVID-19). These adverse outcomes have been suspected to be more severe in patients with lung cancer. The objective of this systematic …

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A Systematic Review and Meta-analysis of Clinical Characteristics and Outcomes in Lung Cancer Patients with COVID-19.

Monica Peravali, Indra Joshi, Joseph Ahn, C Kim

Background: Cancer is considered to be an independent risk factor for severe illness and higher mortality in patients with Coronavirus disease 2019 (COVID-19). These adverse outcomes have been suspected to be more severe in lung cancer patients. The objective of this systematic …

Safety and efficacy of CAR T cells in a patient with lymphoma and a coexisting autoimmune neuropathy

Khushali Jhaveri, Ilana Schlam, Noa G. Holtzman, Monica Peravali et autres

Key Points CAR T-cell therapy was safe and effective in a DLBCL patient with coexisting autoimmune neuropathy. CD19 CAR T-cell therapy may control refractory autoantibodies and monoclonal gammopathies.

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A Prospective Pilot Study to Evaluate Molecular Changes in the Hematopoietic System after Receipt of Chemotherapy or Radiotherapy and Its Clinical Implications Among Racially Diverse Breast Cancer Survivors: Breast Survivorchip Study

Monica Peravali, Chidera Nosiri, Christopher S. Hourigan, Christopher Gallagher et autres

Background: Clonal hematopoiesis (CH) increases in inflammatory states, and in retrospective epidemiological studies, has been associated with increased rates of atherosclerotic coronary artery disease, ischemic stroke, neurocognitive disorders, and hematologic malignancies.Previous data in non-cancer patients reported approximately 5% incidence of CH in …

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