Kai‐Jie Yu

Radium-223 therapy in metastatic castration-resistant prostate cancer: baseline predictors of treatment completion and survival in a reimbursement-regulated Taiwanese cohort

Hsi-Chen Tsai, Jing‐Ren Tseng, Feng‐Yuan Liu, Chun-Te Wu et autres

tw (code pays fourni par la source)

Transurethral prostate resection with high-intensity focused ultrasound achieves a superior functional outcome in prostate cancer patients

Tsu-Chen Lin, Kuan‐Yu Lin, Ming-Chieh Cheng, Chung-Lin Lee et autres

PURPOSE: This study aimed to investigate the role of concurrent transurethral resection of prostate with high-intensity focused ultrasound treatment in decreasing the early post-operative complications. METHODS: A retrospective study was conducted in Linkou Chang Gung Memorial Hospital, a tertiary medical center in …

tw (code pays fourni par la source)

Oncologic outcomes of radical radiotherapy in frail patients with upper tract urothelial carcinoma

Willy Po-Yuan Chen, Wing‐Keen Yap, Hao-Lun Luo, Yao‐Yu Wu et autres

OBJECTIVE: To evaluate oncologic outcomes of high-dose radical radiotherapy (RT) in medically frail patients with upper tract urothelial carcinoma (UTUC). MATERIALS AND METHODS: was 64.8 Gy (interquartile range 60.0-72.0) in the low-dose group and 84.0 Gy (interquartile range 78.4-86.4) in the high-dose …

tw (code pays fourni par la source)

Multiplex biomarker detection platform based on zinc protoporphyrin-modified gold electrodes: Application potential for early diagnosis and postoperative monitoring of prostate cancer

Hung‐Yu Lin, Chin-Cheng Liao, Shin-Ho Tsai, Kai‐Jie Yu et autres

tw, cn (code pays fourni par la source)

A phase 3 randomized, open-label study of pasritamig (JNJ-78278343), a T-cell engager targeting human kallikrein-2, with docetaxel versus docetaxel for metastatic castration-resistant prostate cancer.

Rana R. McKay, Kai‐Jie Yu, Teresa Alonso Gordoa, Johann S. De Bono et autres

TPS5139 Background: Metastatic castration-resistant prostate cancer (mCRPC) remains an incurable disease with high morbidity and a median overall survival of approximately two years. Human kallikrein 2 (KLK2) is highly and specifically expressed in normal and malignant prostate tissue, including late stage mCRPC. …

us, tw, es, gb, de, au, ca, fr, cn (code pays fourni par la source)

Comparable oncological and functional outcomes of robot-assisted radical prostatectomy with conventional anterior approach and Hood technique using DAVINCI SP system

Po‐Hung Lin, Hung‐Jen Wang, Hung-Cheng Kan, See‐Tong Pang et autres

The DAVINCI SP system is an advanced robotic surgery platform allowing an endoscope and three articulated instruments to enter the body through a single incision while maintaining workspace triangulation. This open-label, single-arm clinical trial (ClinicalTrials.gov Identifier: NCT05403190 18/05/2022) evaluates the feasibility of …

tw (code pays fourni par la source)

Silencing IncRNA BACE1-AS alleviates neuronal injury and neurological deficits after ischemic stroke via targeting miR-103a-3p

Kai‐Jie Yu, Fang Liu, Tao Yu, Yanping Ding

OBJECTIVE: To investigate the role of lncRNA BACE1-AS in neuronal injury and neurological deficits after ischemic stroke and explore its underlying molecular mechanism. METHODS: MCAO rat model and OGD/R cell model were established. BACE1-AS expression was detected by RT-qPCR. Neurological function was …

cn (code pays fourni par la source)

Establishment of the recombinase polymerase amplification–lateral flow dipstick (RPA–LFD) detection technique for rapid detection of lymphocystis disease virus (LCDV)

Kai‐Jie Yu, Yitong Zhang, Zi‐Yang He, Yufeng Liu et autres

cn (code pays fourni par la source)

Automated Kidney Tumor Segmentation in CT Images Using Deep Learning: A Multi-Stage Approach

Hung-Cheng Kan, Po‐Hung Lin, I‐Hung Shao, Kai‐Jie Yu et autres

RATIONALE AND OBJECTIVES: Computed tomography (CT) remains the primary modality for assessing renal tumors; however, tumor identification and segmentation rely heavily on manual interpretation by clinicians, which is time-consuming and subject to inter-observer variability. The heterogeneity of tumor appearance and indistinct margins …

tw (code pays fourni par la source)

Rocket-Like Microneedle Patch for Sustained Hormone Therapy in Prostate Cancer

Ying‐Tzu Chen, Kai‐Jie Yu, See-Tong Pang, Hung‐Wei Yang

High Resolution Image Download MS PowerPoint Slide Prostate cancer (PCa) remains a significant global health challenge, necessitating the development of advanced therapeutic strategies. This study introduces a rocket-like microneedle patch (RLMNP) as a dual-layer drug delivery system for sustained hormone therapy in …

tw (code pays fourni par la source)

Multimodal deep learning improving the accuracy of pathological diagnoses for membranous nephropathy

Xiuxiu Hu, Jinyue Yang, Yiping Li, Yuxiang Gong et autres

OBJECTIVES: Renal biopsy is the gold standard for the diagnosis of glomerular diseases including membranous nephropathy (MN), however, it faces challenges in accuracy, objectivity, and reproducibility of tissue evaluation. This study aims to develop a multimodal pathological diagnosis system to assist pathologists …

bd, cn (code pays fourni par la source)

Predicting hemorrhagic complications in robotic-assisted partial nephrectomy for renal tumors: simplifying risk assessment with tumor diameter and depth

I‐Hung Shao, Chung‐Lin Lee, Yu-Hsiang Lin, Hsiang‐Sheng Wang et autres

tw (code pays fourni par la source)