Lei Shi

Sirt1 attenuates calcific aortic valve disease by inhibiting ferroptosis and enhancing mitochondrial function via the activation of the Nrf2/HO‑1/FTH1 axis

Fei Yan, Lei Shi, Yuechan Wang, Ying Zhao et autres

cn (code pays fourni par la source)

miR‐138‐5p Inhibits Aortic Valve Interstitial by Targeting SLC39A14 and Activating Nrf2 Signaling

Fei Yan, Ying Zhao, Yuanyuan Wu, Dubiao Xian et autres

This study explored the role of miR-138-5p in calcific aortic valve disease (CAVD), focusing on its regulation of osteogenic differentiation in human aortic valve interstitial cells (hAVICs) and underlying mechanisms. Aortic valve tissues from CAVD patients and controls were analyzed for miR-138-5p …

cn (code pays fourni par la source)

Long-Term Urban Air Pollution Drives Multi-Stage Neuropsychiatric Disorder Trajectories: A Prospective Cohort Study

Yuanyuan Song, Shiqing Zhang, Siru Yang, Xiaoke Gao et autres

Neuropsychiatric disorders constitute an escalating public health challenge worldwide, with growing evidence suggesting that environmental factors like air pollution may contribute substantially. This prospective cohort study investigated the associations between long-term exposure to fine particulate matter (PM2.5) and nitrogen oxides (NOx) and …

cn, fr (code pays fourni par la source)

Transient Receptor Potential Channels as Key Regulators of Neuroinflammation in Neurological Disorders: Mechanistic Insights, Therapeutic Potentials, and Future Directions

Daji Guo, Yinyin Chen, Yujun Feng, Chun Hu et autres

BACKGROUND: Transient receptor potential (TRP) ion channels, a ubiquitous family of nonselective cation channels, are extensively expressed across the nervous system, immune system, and peripheral tissues. These channels serve as critical sensors for detecting temperature, mechanical forces, and chemical stimuli, thereby regulating …

cn, Rwanda, fr (code pays fourni par la source)

Retraction Note: CD142 promotes trophoblast cell migration by inhibiting BCL2-related autophagic degradation of IL-8

Linmei Zheng, Rong Tang, Lei Shi, Zhongyi Zhou et autres

cn (code pays fourni par la source)

IGF2BP1 positively regulates CircOGDH accumulation in hypoxia induced stress granules

Xuanlin Su, Jiankun Zang, Shiqing Zhang, Ping Wu et autres

The ischemic penumbra is critical in acute ischemic stroke (AIS) treatment, yet the regulation of precise RNA modification pathways remains unclear. Using a mouse model of ischemic stroke and human postmortem brain samples, we demonstrate that N 6- methyladenosine (m 6 A) …

cn (code pays fourni par la source)

The Impact of Environmental Regulations on Energy-Environmental Efficiency: Evidence from China

Zhanyu Yang, Dong Le, Lei Shi

Within the context of Carbon Peaking and Carbon Neutrality objectives, reducing carbon emissions and improving energy-environmental efficiency have emerged as the primary concerns of China’s environmental governance. It will become increasingly important to study how environmental regulation can improve the environmental efficiency …

br, cn (code pays fourni par la source)

An analysis of the therapeutic efficacy and underlying mechanisms of combining lycopene with dental pulp stem cells to ameliorate alzheimer’s disease in rats

Zhiguo Xu, Yi Zhun Zhu, Lefeng Liu, Chao Liu et autres

cn (code pays fourni par la source)

Polysaccharides isolated from shufeng jiedu capsules by cross-flow ultrafiltration show anti-inflammatory effects on LPS-stimulated RAW264.7 cells and zebrafish inflammatory models

Dongsheng Du, Ziyi Huang, Mingzhu Gao, Ruirui Su et autres

cn (code pays fourni par la source)

Polysaccharides Isolated from Shufeng Jiedu Capsules by Cross-Flow Ultrafiltration Show Anti-Inflammatory Effects on Lps-Stimulated Raw264.7 Cells and Zebrafish Inflammatory Models

Dongsheng Du, Ziyi Huang, Mingzhu Gao, Ruirui Su et autres

cn (code pays fourni par la source)

Utility of preoperative 18F-flurodeoxyglucose PET/CT scanning in preoperative evaluation and surgical planning for pulmonary tuberculosis

Leilei Li, Lin Wang, Hongwei Li, Hui Chen et autres

OBJECTIVE: The objective of this study was to investigate the utility of preoperative 18F-FDG PET/CT scanning in preoperative evaluation and surgical planning for pulmonary tuberculosis. METHODS: The study involved a retrospective analysis of clinical data and preoperative chest 18F-FDG PET/CT data of …

cn (code pays fourni par la source)

Lentinan combined with docetaxel and nedaplatin in the treatment of pulmonary tuberculosis complicated by nonsmall cell lung cancer

Dingjun Wang, Lei Shi

Purpose: To investigate the efficacy and safety of lentinan combined with docetaxel and nedaplatin (DN) in the treatment of pulmonary tuberculosis complicated by non-small cell lung cancer (NSCLC). Methods: A total of 100 patients diagnosed with pulmonary tuberculosis combined with NSCLC in …

au, cn (code pays fourni par la source)