Yujie Zhang

Advances in Single-Cell Metabolomics and Their Applications in Disease Biology

Jie Du, Huihui Tao, Yujie Zhang, Mengyao Wu et autres

Single-cell metabolomics (SCM) provides a functional view of cellular heterogeneity by measuring metabolic states at cellular or subcellular resolution. Unlike bulk metabolomics, SCM can reveal rare metabolic cell states, spatially restricted metabolic niches, dynamic pathway activity, and treatment-associated metabolic adaptations. This review …

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A Multi-omics PTM Atlas Reveals Key Insights into Metabolic Reprogramming in Colorectal Cancer

Tianyuan Li, Jingjing Dong, Yujie Zhang, 浩二 角 et autres

BACKGROUND/AIM: Colorectal cancer (CRC) is a leading cause of cancer-related mortality worldwide, with limited effective targeted therapies. Metabolic reprogramming is a hallmark of cancer, and post-translational modifications (PTMs), such as phosphorylation, ubiquitination, and malonylation, play critical roles in regulating metabolic pathways. However, …

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A Multi-PTM omics atlas uncovers novel aging regulators in colorectal cancer

Yujie Zhang, Wei Zhang, Tianyuan Li, Jie Du et autres

BACKGROUND: Aging is a key driver of colorectal cancer (CRC) progression, yet the post-translational modification (PTM) landscape associated with aging in CRC remains largely uncharacterized. In particular, the coordinated influence of multiple PTMs-such as phosphorylation, ubiquitination, and malonylation-on aging-related pathways has not …

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Table S2 from Tumor-Derived CCL16 Normalizes Tumor Vasculature through Macrophage ICAM-1 Receptor and Enhances Immunotherapy Efficacy in Hepatocellular Carcinoma

Kunling Chen, Huolun Feng, Yujie Zhang, Jingyuan Pei et autres

Oligonucleotide information, related to STAR Methods.

Identification of the Potential Prognosis Biomarkers in Hepatocellular Carcinoma: An Analysis Based on WGCNA and PPI

Jinlin Huang, Yihua Zhan, Leiyu Jiang, Gao Y et autres

Junting Huang,1,* Yating Zhan,1,* Lili Jiang,1,* Yuxiang Gao,1,* Binyu Zhao,1,* Yuxiao Zhang,1 Wenjie Zhang,1 Jianjian Zheng,1 Jinglu Yu2,3 1Key Laboratory of Diagnosis and Treatment of Severe Hepato-Pancreatic Diseases of Zhejiang Province, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, People’s …