Remy F. Pasco

Modeling the Impact of Pediatric RSV Immunization in Massachusetts, 2024–2025

L. Jones, Rosa Ergas, Andrew Tibbs, Elizabeth T Russo et autres

Abstract Background Pediatric immunizations for Respiratory Syncytial Virus (RSV), including monoclonal antibodies for infants and vaccines for pregnant people, have become broadly available and can prevent severe RSV outcomes in infants. However, quantifying the impact of RSV immunization in prevention of severe …

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Community risk, mobility patterns, and COVID-19 hospitalization risk: A ZIP code–level analysis using mobile-device data (Preprint)

José Luís Herrera, Dongah Kim, Shraddha Ramdas Bandekar, Emily M. Javan et autres

BACKGROUND The COVID-19 pandemic revealed substantial disparities in health outcomes across U.S. communities. High-resolution mobility data offer new opportunities for real-time surveillance of behavioral responses, yet less is known about how precautionary behavior varied within cities and how these differences were associated …

Community risk, mobility patterns, and COVID-19 hospitalization risk in Texas: A ZIP code–level ecological longitudinal study (Preprint)

Jose Herrera-Diestra, Dongah Kim, Shraddha Ramdas Bandekar, Emily M. Javan et autres

Modeling Influenza Antiviral Strategies: Reducing Burden and Preventing Resistance

Remy F. Pasco, Frederick G. Hayden, Lauren Ancel Meyers

Annually, influenza epidemics lead to hundreds of thousands of deaths worldwide many more hospitalizations. The antivirals baloxavir and oseltamivir improve outcomes and limit virus spread, but their widespread use may accelerate the emergence of drug-resistant influenza variants, particularly in young children. Using …

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Effectiveness of interventions to reduce COVID-19 transmission in schools

Remy F. Pasco, Spencer J. Fox, Michael Lachmann, Lauren Ancel Meyers

School reopenings in 2021 and 2022 coincided with the rapid emergence of new SARS-CoV-2 variants in the United States. In-school mitigation efforts varied, depending on local COVID-19 mandates and resources. Using a stochastic age-stratified agent-based model of SARS-CoV-2 transmission, we estimate the …

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Optimizing COVID-19 testing strategies on college campuses: Evaluation of the health and economic costs

Kaitlyn E. Johnson, Remy F. Pasco, Spencer Woody, Michael Lachmann et autres

Colleges and universities in the US struggled to provide safe in-person education throughout the COVID-19 pandemic. Testing coupled with isolation is a nimble intervention strategy that can be tailored to mitigate the changing health and economic risks associated with SARS-CoV-2. We developed …

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Multimodeling approach to evaluating the efficacy of layering pharmaceutical and nonpharmaceutical interventions for influenza pandemics

Pragati Venkata Prasad, Molly K. Steele, Carrie E. Reed, Lauren Ancel Meyers et autres

When an influenza pandemic emerges, temporary school closures and antiviral treatment may slow virus spread, reduce the overall disease burden, and provide time for vaccine development, distribution, and administration while keeping a larger portion of the general population infection free. The impact …

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Disproportionate impacts of COVID-19 in a large US city

Spencer J. Fox, Emily M. Javan, Remy F. Pasco, Graham Gibson et autres

COVID-19 has disproportionately impacted individuals depending on where they live and work, and based on their race, ethnicity, and socioeconomic status. Studies have documented catastrophic disparities at critical points throughout the pandemic, but have not yet systematically tracked their severity through time. …

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Multiple models for outbreak decision support in the face of uncertainty

Katriona Shea, Rebecca K. Borchering, William J. M. Probert, Emily Howerton et autres

Policymakers must make management decisions despite incomplete knowledge and conflicting model projections. Little guidance exists for the rapid, representative, and unbiased collection of policy-relevant scientific input from independent modeling teams. Integrating approaches from decision analysis, expert judgment, and model aggregation, we convened …

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COVID-19 Test Allocation Strategy to Mitigate SARS-CoV-2 Infections across School Districts

Remy F. Pasco, Kaitlyn E. Johnson, Spencer J. Fox, Kelly A. Pierce et autres

B y early January 2023, the COVID-19 pandemic had caused >6.7 million deaths worldwide (1), and severe socioeconomic hardship (2-4), particularly for racial minorities (5,6).Children experienced pandemic-related school closures that led to substantial losses in learning (7-9), elevated rates of child abuse …

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Optimizing COVID-19 testing strategies on college campuses: evaluation of the health and economic costs

Kaitlyn E. Johnson, Remy F. Pasco, Spencer Woody, Michael Lachmann et autres

Abstract Colleges and universities in the US struggled to provide safe in-person education throughout the COVID-19 pandemic. Testing coupled with isolation is a nimble intervention strategy that can be tailored to mitigate health and economic costs, as the virus and our arsenal …

us (code pays fourni par la source)

Disproportionate impacts of COVID-19 in a large US city

Spencer J. Fox, Emily M. Javan, Remy F. Pasco, Graham Gibson et autres

Abstract COVID-19 has disproportionately impacted individuals depending on where they live and work, and based on their race, ethnicity, and socioeconomic status. Studies have documented catastrophic disparities at critical points throughout the pandemic, but have not yet systematically tracked their severity through …

us (code pays fourni par la source)