Elizabeth Long O’Connell

95 CholeS Passes the Test

Vasiliki Tzamou, Elizabeth Long O’Connell, Benjamin Kai Yan Chan, Klaire Exarchou et autres

Abstract Background With ∼66,660 cholecystectomies performed annually in the UK, it would be beneficial to better stratify predicted operating difficulty and time to improve theatre utilisation and thus optimise patient care and hospital productivity. The CholeS score is a predictive model for …

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232 Case Report: A Case of Recurrent Boerhaave’s Syndrome

Elizabeth Long O’Connell, Tasnim Kouli, Klaire Exarchou, Catherine Bell et autres

Abstract Introduction Boerhaave’s syndrome is a rare but potentially life-threatening rupture of the oesophagus. Despite advances in diagnosis and management, it still has a high mortality rate. While single episodes of Boerhaave’s syndrome are uncommon, recurrent spontaneous oesophageal perforations are exceedingly rare. …

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378 Mind the Gap: Radiological-Pathological Discrepancies After FLOT in Gastric Cancer

Vasiliki Tzamou, Mushfique Alam, Elizabeth Long O’Connell, Nathan Howes et autres

Abstract Aim Perioperative chemotherapy is the standard of care for resectable gastric cancer in the United Kingdom, with CT imaging routinely used before and after neoadjuvant chemotherapy (NAC) to assess tumour response. This study aimed to evaluate concordance between initial radiological staging …

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226 The Role of CRP in Early Detection of Anastomotic Leak After Oesophagogastric Resections: A Single Centre Study

Elizabeth Long O’Connell, Catherine Bell, Klaire Exarchou, Yan Mei Goh et autres

Abstract Aim Anastomotic leak remains a significant source of morbidity and mortality following oesophagogastric resections. Early detection is essential in this high-risk population. C-reactive protein (CRP) is a well-established marker of post-operative complications. This study aimed to assess the association between early …

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Raw milk consumption and other early-life farm exposures and adult pulmonary function in the Agricultural Lung Health Study

Annah B. Wyss, John S. House, Jane A. Hoppin, Marie Richards et autres

Literature suggests that early exposure to the farming environment protects against atopy and asthma; few studies have examined pulmonary function. We evaluated associations between early-life farming exposures and pulmonary function in 3061 adults (mean age=63) from a US farming population using linear …

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House Dust Endotoxin Levels Are Associated with Adult Asthma in a U.S. Farming Population

Megan Ulmer Carnes, Jane A. Hoppin, Nervana Metwali, Annah B. Wyss et autres

Abstract Rationale Endotoxin initiates a proinflammatory response from the innate immune system. Studies in children suggest that endotoxin exposure from house dust may be an important risk factor for asthma, but few studies have been conducted in adult populations. Objectives To investigate …

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Early-life farm exposures and adult asthma and atopy in the Agricultural Lung Health Study

John S. House, Annah B. Wyss, Jane A. Hoppin, Marie Richards et autres

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