Yi Zou

Reality-anchored generative gating enables robust morphological classification and metacognitive triage of leukemia

Zhigang Yang, Shah Faisal, Zhao Hui, Zhangyue Wu et autres

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Photothermal conversion and antitumor effects of a bis triphenylamine-conjugated hemicyanine dye with deep near-infrared absorption and NIR-II emission

YANG Zhigang, ZHANG Ziyan, Shiqing Zhang, WU Xianghua et autres

近红外二区有机小分子光热剂具有结构明确、光谱可调和生物应用适配性好的特点，但如何在同一实验体系中建立分子结构、光谱响应、光热转换效率和生物效应之间的关联，仍是小分子光热剂研究中的重要问题。本文研制了一种近红外二区双三苯胺共轭半菁染料ZZ，并围绕其分子设计、稳态光谱、光热转换性能及抗肿瘤效应开展系统性研究。ZZ由三苯胺给电子单元和扩展半菁共轭结构组成，表现出深近红外吸收峰约位于850 nm，发射覆盖950-1300 nm。在100 μM DMSO体系中，808 nm激光照射下最大升温幅度为19.5℃，光热转换效率为76.1%，显著优于商用对比试剂吲哚菁绿（ICG）；ZZ在激光循环照射中保持良好的热稳定性，在琼脂糖凝胶及4T1细胞等复杂介质模型中表现出光热积累效应和细胞杀伤能力。4T1荷瘤小鼠实验表明，瘤内注射ZZ后在激光照射下形成局部热场，显著抑制实体肿瘤生长，具有肿瘤治疗潜在性；体重曲线和主要脏器H&E染色表明ZZ在本研究给药条件下具有较好生物相容性。结果说明，所研制的新型近红外二区小分子光热剂ZZ，具有高效的二区近红外光热转换效率，在实体瘤内产生稳定热输出，具有潜在的肿瘤治疗价值，为小分子光热剂优化及纳米递送体系构建提供理论基础。

Mid‐Infrared on‐Chip Dichroic Filters Enabled by Adiabatic Evolution and Dispersion‐Engineered Subwavelength Grating Waveguides

Yuheng Liu, Wenchen Yin, Yuhan Sun, Lipeng Xia et autres

ABSTRACT Broadband high‐performance optical filters are fundamental building blocks for advancing mid‐infrared (MIR) integrated photonics, particularly for applications in molecular sensing and free‐space communication. Although dichroic filters offer robust high‐roll‐off performance in the near‐infrared, their realization in the critical MIR atmospheric transparency …

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Topological photonic crystal triangular micro-cavity for on-chip gas sensing

Mojtaba Hosseinzadeh Sani, Zhiqian Zhang, Si Chen, Hong Zhang et autres

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Bamboo-culm-inspired graded axial channel cellulose cryogels for acoustic absorption and acoustoelectric conversion

Xichen Yu, Jinan Huang, Yi Zou, Zhuqun Shi et autres

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First Demonstration of Broadband Internal Gain in Bismuth-Doped GeSe 4 Waveguide

Qi Cheng, Zhe Long, Lei Qian, Yi Zou et autres

We prepared bismuth (Bi)-doped GeSe₄ chalcogenide thin films via ion beam sputtering and fabricated ridge waveguides using standard photolithography. The waveguide exhibited a propagation loss of 3.7 dB/cm at 1500 nm. Under a signal power of -43.8 dBm and a pump power …

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Accelerated exceptional point encirclement in anti-parity-time symmetric systems for ultra-compact chiral mode switching

Yuhan Sun, Hong Zhang, Lipeng Xia, Xiaochuan Xu et autres

Anti-parity-time (anti-PT) symmetric systems have emerged as promising tools in optical design, offering unique advantages over parity-time (PT) symmetric systems. These systems leverage symmetry-broken modes, which play a crucial role in enabling chiral mode switching—a key functionality for integrated photonic devices. However, …

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High Quality Factor, High Sensitivity Ta 2 O 5 Microring Resonator for Biochemical Sensing

Zheng Zhang, Peng Chen, Zhe Long, Qi Cheng et autres

We demonstrate a high-performance Ta.O. microring resonator fabricated using electron-beam lithography and inductively coupled plasma etching. The loaded Q-factor of the fundamental TE mode reaches 3.1 × 105at 1550 nm under ambient conditions, with post-annealing at 600$^{\circ }$C further elevating this value …

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High-Precision Large-Scale Optical Phased Array Calibration Using Physics-Informed Neural Network With Transfer Learning

Wanchang Gao, Weiming Yao, Jinzhao Wang, Yanmei Li et autres

As the number of elements in integrated optical phased arrays (OPAs) continues to scale up, the complexity of calibration and controlling these independent channels becomes prohibitive. To address this challenge, this study presents a physics-informed neural network (PINN)-based phase calibration algorithm that …

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Photothermal ATP detection by competitive displacement of ZIF-67 adsorbed G4-dHemin DNAzyme

Xiao‐Tao He, Xiaoting Xu, Qian Xiao, Qiuyi Li et autres

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Low‐Threshold Chirality‐Enabled Silicon Photonic Diode

Jiewen Li, Ke Li, Wanxin Li, Jinzhao Wang et autres

Abstract Optical nonlinearity offers a promising pathway for advancing passive silicon photonic diodes and enabling precise control of on‐chip light flow. However, the realization of nonlinearity‐based photonic diodes often requires high‐power excitation, a common constraint in conventional nonlinear devices. In this study, …

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All‐Zero Tunneling Rates in an Ultra‐Dense Waveguide Array

Peiji Zhou, Hong Zhang, Yuheng Liu, Yuhan Sun et autres

Abstract Quantum tunneling, a well‐known phenomenon in finite deep potential wells, serves as the foundation for constructing scanning tunneling microscopes and tunneling diodes. While this phenomenon has proven valuable in integrated devices, it can pose challenges, introducing leakage current in electronic devices …

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