Liviu Moraru

Multidrug Resistance, Antimicrobial Therapy, and In-Hospital Mortality in Patients with Healthcare-Associated Infections: A Retrospective Cohort Study

Septimiu Voidăzan, Réka Bodea, Liviu Moraru, Iuliu Moldovan et autres

Background: Healthcare-associated infections (HAIs), particularly those caused by an-timicrobial-resistant pathogens, remain an important cause of adverse outcomes among hospitalized patients. The combined contribution of antimicrobial resistance, clinical characteristics, and antimicrobial treatment to mortality requires further evaluation. This study aimed to investigate factors …

Effect of Topically Administered Natural Compounds on Cesarean Section Healing—A Retrospective Observational Study

Melinda-Ildiko Mitranovici, Raluca Moraru, Septimiu Voidăzan, Corneliu-Florin Buicu et autres

Natural compounds in topical gel formulations are recognized for their ability to enhance wound healing, particularly in the context of postoperative care, including that of cesarean sections. Background: Cesarean sections are among the most common surgical procedures globally, highlighting the importance of …

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Post-Surgical Evaluation in Stress Urinary Incontinence by Transperineal Ultrasound and Quality of Life Questionnaire—A Retrospective Study

Melinda-Ildiko Mitranovici, Laura Georgiana Caravia, Ion Petre, Septimiu Voidăzan et autres

Urinary incontinence, the involuntary leakage of urine, significantly impacts middle-aged women. Background/Objective: In response to the failure of traditional diagnostic methods, transperineal ultrasound (TPUS) imaging was developed. The aim of our study was to identify the utility of TPUS in combination with …

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Intraoperative Dynamics of Lactate, pH, and Bicarbonate During Cardiac Surgery: A Prospective Study Exploring a Composite Metabolic Marker of Reperfusion Stress

Andrei Raicea, Liviu Moraru, Victor Raicea

Background: Myocardial ischemia–reperfusion during cardiac surgery is associated with complex metabolic alterations that reflect both myocardial injury and recovery. This prospective study aimed to characterize intraoperative lactate, pH, and bicarbonate dynamics in paired coronary sinus (CS) and peripheral blood samples and to …

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Nanomedicine-Mediated Autophagy Modulation in Placental Impairment Versus Cancers: A Narrative Review

Melinda-Ildiko Mitranovici, Viviana Mihaela Ivan, Adrian Apostol, Liviu Moraru et autres

The biggest challenge faced by classical anticancer therapy is drug resistance, which causes cancer recurrence and metastasis. Two underlying mechanisms could be responsible, including the stemness of pro-survival autophagy-associated cancer stem cells (CSCs). Background/Objectives: The relationship between CSCs and autophagy in gynecological …

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Predictors of Abnormal Transfontanelle Ultrasound Findings in Neonates with Congenital Heart Disease

Liviu Moraru, Petra-Caroline Mayaya, Elena Hanganu, Raluca Moraru et autres

ABSTRACT Background Advances in neonatal cardiac care have improved survival in infants with congenital heart disease (CHD), shifting clinical attention toward early neurological morbidity. While cardiac anatomical complexity has traditionally been considered a major determinant of brain injury, emerging evidence suggests that …

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Correlations Between Ultrasound Features and Histological Findings in Adenomyosis: A Single-Center Retrospective Study

Melinda-Ildiko Mitranovici, Dan Costăchescu, Septimiu Toader Voidăzan, Liviu Moraru et autres

Adenomyosis is a benign gynecologic condition characterized by ectopic endometrial glands and stroma present within the myometrium. Background/Objectives: The gold standard in diagnosis is the histology of hysterectomy specimens. Due to the heterogeneity of this disease, there is a lack of valid …

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Altered PAPP-A and Placental Thickness in Pre-Eclampsia and Intrauterine Growth Restriction: A Pilot Study

Liviu Moraru, Raluca Moraru, Melinda-Ildiko Mitranovici, Romeo Micu

Pre-eclampsia (PE) is a multisystem disorder that affects 5–6% of all pregnancies. Background: PE and intrauterine growth restriction (IUGR) are two major causes of maternal mortality and morbidity. We hypothesize that first-trimester pregnancy-associated plasma protein-A (PAPP-A) levels are useful as a prognostic …

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Histopathological Characteristics of Placenta in Pregnancies Complicated by Intrauterine Growth Restriction—A Pilot Study

Liviu Moraru, Raluca Moraru, Diana Maria Chiorean, Septimiu Voidăzan et autres

Background/Objectives: Intrauterine growth restriction (IUGR) is a condition in which a fetus does not reach its normal growth potential and is associated with increased neonatal morbidity. Surveillance relies on cardiotocography, a biophysical ultrasound, and a Doppler assessment, but placental pathology remains insufficiently …

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The Association of Coronary Artery Calcium Score with Heart Failure – a Literature Review

Daniel Stirbu, Grigore Tinică, Liviu Moraru, Klara Brînzaniuc et autres

ABSTRACT One of the main principles of cardiovascular disease prevention is early intervention. Heart failure represents an end stage of most cardiovascular diseases and is a consequence of persistent damage caused by conditions such as coronary artery disease, hypertension, or valvular heart …

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Divergent perspectives among medical and non-medical personnel implications in the context of the Covid-19 pandemic

Liviu Moraru, Réka Bodea, Dana Bădău, Raluca Moraru

In Romania, an increased number of infections with the new coronavirus have been reported, which has led to the deterioration of the state medical system, already facing multiple problems due to outdated infrastructure, lack of equipment and lack of personnel. Lack of …

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Burden of Healthcare-Associated Infections and Antimicrobial Resistance in a Romanian Cardiovascular and Transplant Center: Factors Associated with Mortality

Mihaela-Alexandra Budianu, Cristina Nicoleta Ciurea, Liviu Moraru, Septimiu Toader Voidăzan

Background/Objectives: Healthcare-associated infections (HAIs) are a major burden in tertiary hospitals, particularly in high-risk populations such as cardiovascular and transplant patients. The emergence of antimicrobial resistance (AMR) further complicates management, contributes to poor outcomes and increases costs. This study aimed to describe …

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