Mihaela Ştefana Moldovan

Discovery of a Secretory Granule Lumen-Enriched Serum Protein Signature in Resectable Pancreatic Ductal Adenocarcinoma

Septimiu Alex Moldovan, Maria Iacobescu, Emil Ioan Moiș, Florin Graur et autres

Background and Objectives: Serum biomarker discovery in resectable pancreatic ductal adenocarcinoma (PDAC) remains a critical unmet need, as over 80% of patients present with unresectable disease. Serum proteomics offers a promising approach for identifying circulating biomarkers associated with early-stage disease; however, clinical …

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Comparative Outcomes of Pancreaticogastrostomy and Pancreaticojejunostomy Following Pancreaticoduodenectomy: A Retrospective Cohort Study from a Romanian High-Volume Center

Septimiu Alex Moldovan, Emil Ioan Moiș, Florin Graur, Vlad-Ionuț Nechita et autres

Background and Objectives: Pancreaticogastrostomy (PG) and pancreaticojejunostomy (PJ) are the two most frequently employed reconstruction techniques following pancreaticoduodenectomy (PD), yet the optimal method remains debated. The objective of this study was to compare perioperative outcomes of PG versus PJ in patients undergoing …

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Comparative Outcomes of Pancreaticogastrostomy and Pancreaticojejunostomy Following Pancreaticoduodenectomy for Resectable Periampullary Tumors: A Retrospective Cohort Analysis

Septimiu Alex Moldovan, Emil Ioan Moiș, Florin Graur, Vlad-Ionuț Nechita et autres

Background/Objectives: Pancreaticogastrostomy (PG) and pancreaticojejunostomy (PJ) are the two most frequently employed reconstruction techniques following pancreaticoduodenectomy (PD), yet the optimal method remains debated. The objective of this study was to compare perioperative outcomes of PG versus PJ in patients undergoing PD for …

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A Systematic Review and Meta-Analysis of Preoperative Biliary Drainage Methods in Periampullary Tumors

Septimiu Alex Moldovan, Emil Ioan Moiș, Florin Graur, Ion Cosmin Puia et autres

Background: Pancreatic and hepatobiliary tumors continue to rank among the deadliest cancers worldwide. Due to a low response rate to treatment, these tumors continue to have a high death rate, a poor prognosis and survival rate, and an overall poor patient outcome. …

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Biliary Drainage for the Preoperative Management of Periampullary Neoplasms: A Retrospective Cohort Study

Septimiu Alex Moldovan, Emil Ioan Moiș, Florin Graur, Vlad-Ionuț Nechita et autres

Background and Objectives: Preoperative biliary drainage (PBD) in patients with periampullary neoplasms remains a debated topic, with various techniques available and conflicting evidence regarding their impact on postoperative outcomes. This study aimed to assess, in a high-volume pancreatic surgery center, whether the …

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Antimicrobial Meshes for Hernia Repair: Current Progress and Perspectives

Simona Mirel, Alexandra Pusta, Mihaela Ştefana Moldovan, Septimiu Alex Moldovan

Recent advances in the development of biomaterials have given rise to new options for surgery. New-generation medical devices can control chemical breakdown and resorption, prevent post-operative adhesion, and stimulate tissue regeneration. For the fabrication of medical devices, numerous biomaterials can be employed, …

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P857: Thoracic outlet syndrome with more than 8 years subclavian artery involvement?

B. Catalin, M. Iancau, Mihaela Ştefana Moldovan