Emil Moiş

Exploratory Analysis of Factors Associated with Conversion After Initially Attempted Laparoscopic Appendectomy in Children: The Role of Inflammatory Markers and Clinical Scores

Paul Tchouala Tchakoute, Alin Iuhas, Vlad-Ionuț Nechita, Kinga Kozma et autres

Background: Acute appendicitis is the leading pediatric surgical emergency. Identifying drivers of disease severity and laparoscopic-to-open conversion remains critical for surgical planning. We evaluated the discriminative performance of clinical scores and inflammatory biomarkers for both peritonitis and surgical conversion, and explored combined …

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Correction: Ten years of the European association of endoscopic surgery (EAES) fellowship programme: outcomes and future perspective

Andrea Balla, Pietro Mascagni, Miloš Bjelović, Marek Šoltés et autres

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AI-guided additive scoring model for differential diagnosis of primary liver cancer

Rebekka J.S. Salzmann, Tudor Mocan, Arnulf Willms, Angelina Klein et autres

Background & Aims Within the Liver Imaging Reporting and Data System (LI-RADS), LI-RADS Malignant (LR-M) lesions remain diagnostically challenging: imaging indicates malignancy but often fails to distinguish hepatocellular carcinoma (HCC) from intrahepatic cholangiocarcinoma (iCCA). Established serum-based tools such as GALAD are optimized …

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Discovery of a Secretory Granule Lumen-Enriched Serum Protein Signature in Resectable Pancreatic Ductal Adenocarcinoma

Septimiu Moldovan, Maria Iacobescu, Emil Moiş, Florin Graur et autres

Background and Objectives: Serum biomarker discovery in resectable pancreatic ductal adenocarcinoma (PDAC) remains a critical unmet need, as over 80% of patients present with unresectable disease. Serum proteomics offers a promising approach for identifying circulating biomarkers associated with early-stage disease; however, clinical …

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Ten years of the European association of endoscopic surgery (EAES) fellowship programme: outcomes and future perspective

Andrea Balla, Pietro Mascagni, Miloš Bjelović, Marek Šoltés et autres

es, it, fr, ba, rs, sk, se (code pays fourni par la source)

AI-Guided Small-EV and Serum Biomarker Scoring Distinguishes HCC from iCCA and Mirrors Patient Survival in LR-M Lesions

RJ. S. Salzmann, L P Mocan, A G Willms, Emil Moiş et autres

Background Differentiating hepatocellular carcinoma (HCC) from intrahepatic cholangiocarcinoma (iCCA) in radiologically indeterminate liver lesions (LR-M) remains clinically and therapeutically consequential. Because overall survival differs markedly between these trajectories, biomarkers that improve diagnosis and enable early prognostic stratification could guide curative versus palliative …

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Comparative Outcomes of Pancreaticogastrostomy and Pancreaticojejunostomy Following Pancreaticoduodenectomy: A Retrospective Cohort Study from a Romanian High-Volume Center

Septimiu Moldovan, Emil Moiş, Florin Graur, Vlad-Ionuț Nechita et autres

Background and Objectives: Pancreaticogastrostomy (PG) and pancreaticojejunostomy (PJ) are the two most frequently employed reconstruction techniques following pancreaticoduodenectomy (PD), yet the optimal method remains debated. The objective of this study was to compare perioperative outcomes of PG versus PJ in patients undergoing …

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Differential Metabolic Dysregulations in Hepatocellular Carcinoma and Cirrhosis: Insights into Lipidomic Signatures

Cristina-Paula Ursu, Luminița Furcea, Bogdan Procopeț, Răzvan Alexandru Ciocan et autres

Hepatocellular carcinoma (HCC), the most common primary liver malignancy, usually develops in patients with cirrhosis, yet the metabolic mechanisms that distinguish the two conditions remain poorly understood. This study aimed to explore metabolic dysregulations in HCC compared with cirrhosis and to identify …

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Comparative Outcomes of Pancreaticogastrostomy and Pancreaticojejunostomy Following Pancreaticoduodenectomy for Resectable Periampullary Tumors: A Retrospective Cohort Analysis

Septimiu Moldovan, Emil Moiş, Florin Graur, Vlad-Ionuț Nechita et autres

Background/Objectives: Pancreaticogastrostomy (PG) and pancreaticojejunostomy (PJ) are the two most frequently employed reconstruction techniques following pancreaticoduodenectomy (PD), yet the optimal method remains debated. The objective of this study was to compare perioperative outcomes of PG versus PJ in patients undergoing PD for …

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A Systematic Review and Meta-Analysis of Preoperative Biliary Drainage Methods in Periampullary Tumors

Septimiu Moldovan, Emil Moiş, Florin Graur, Ion Cosmin Puia et autres

Background: Pancreatic and hepatobiliary tumors continue to rank among the deadliest cancers worldwide. Due to a low response rate to treatment, these tumors continue to have a high death rate, a poor prognosis and survival rate, and an overall poor patient outcome. …

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Biliary Drainage for the Preoperative Management of Periampullary Neoplasms: A Retrospective Cohort Study

Septimiu Moldovan, Emil Moiş, Florin Graur, Vlad-Ionuț Nechita et autres

Background and Objectives: Preoperative biliary drainage (PBD) in patients with periampullary neoplasms remains a debated topic, with various techniques available and conflicting evidence regarding their impact on postoperative outcomes. This study aimed to assess, in a high-volume pancreatic surgery center, whether the …

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Influence of SARS-CoV2 Pandemic on Colorectal Cancer Diagnosis, Presentation, and Surgical Management in a Tertiary Center: A Retrospective Study

Roman Țăulean, Roxana Zaharie, Dan Vălean, Lia Oxana Usatiuc et autres

Background: Oncological surgery during the COVID-19 pandemic was performed only in carefully selected cases, due to variation in the allocation of resources. The purpose of this study was to highlight the impact of the pandemic lockdown on the presentation, diagnosis, and surgical …

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