Philipp Koellinger

Genomics of Educational Attainment Across 80 Years of Social and Political Transformation in Germany

Deniz Fraemke, Anna Miller, Philipp Koellinger, Ralph Hertwig et autres

Abrupt social and political transformations in twentieth-century Germany may have shifted how polygenic indices relate to educational outcomes across birth cohorts. Following a prespecified analysis plan, we harmonized genomic, educational, and regional data from four German studies, comprising 13,049 individuals born between …

de, nl, us, in, it, gb (code pays fourni par la source)

Distributed Open Science in Practice

András Hartmann, AGM Fox, Elisabeth Julie Vargo, Marta Miklikowska et autres

Scientific research is increasingly global, digital, and interdisciplinary, yet its organizational structures remain largely centralized within institutional and geographic boundaries and constraints. This creates barriers to participation, limits inclusiveness, and constrains innovation, particularly for independent, early-career, and geographically dispersed researchers. At the …

se, ua, it, Somalie, Nigéria, us, id, es, al, nl (code pays fourni par la source)

Distributed Open Science in Practice

András Hartmann, AGM Fox, Elisabeth Julie Vargo, Marta Miklikowska et autres

Scientific research is increasingly global, digital, and interdisciplinary, yet its organizational structures remain largely centralized within institutional and geographic boundaries and constraints. This creates barriers to participation, limits inclusiveness, and constrains innovation, particularly for independent, early-career, and geographically dispersed researchers. At the …

se, ua, it, Somalie, Nigéria, us, id, es, al, nl (code pays fourni par la source)

Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

Ernst Fehr, Remy Z. Levin, Ann H. Caplin, Pierre Fontanillas et autres

us (code pays fourni par la source)

An Updated Polygenic Index Repository: Expanded Phenotypes, New Cohorts, and Improved Causal Inference

Aysu Okbay, Robel G. Alemu, Anastasia Terskaya, Matthew Howell et autres

us, es, gb, nz, ee, de, nl, se (code pays fourni par la source)

Polygenic Associations With Educational Attainment in East Versus West Germany: Differences Emerge After Reunification

Deniz Fraemke, Yayouk Eva Willems, Aysu Okbay, Ulman Lindenberger et autres

Using a DNA-based polygenic index, we explored geographical and historical differences in polygenic associations with educational attainment in East and West Germany around the time of reunification. This index was derived from a prior genome-wide association study on educational attainment in democratic …

de, nl, in, us (code pays fourni par la source)

An Updated Polygenic Index Repository: Expanded Phenotypes, New Cohorts, and Improved Causal Inference

Robel G. Alemu, Anastasia Terskaya, Matthew D. Howell, Junming Guan et autres

Polygenic indexes (PGIs) - DNA-based predictors of individual phenotypes - have become essential tools across biomedical and social sciences. We introduce Version 2 of the Polygenic Index Repository, which expands phenotype coverage from 47 to 61, increases the number of participating datasets …

us, au, es, gb, nz, ca, ee, de, ch, nl, se (code pays fourni par la source)

Author response for "Polygenic Associations With Educational Attainment in East Versus West Germany: Differences Emerge After Reunification"

Deniz Fraemke, Yayouk Eva Willems, Aysu Okbay, Ulman Lindenberger et autres

Deciphering the influence of socioeconomic status on brain structure: insights from Mendelian randomization

Charley Xia, Yunfeng Lu, Zhuzhuoyu Zhou, Mattia Marchi et autres

Socioeconomic status (SES) influences physical and mental health, however its relation with brain structure is less well documented. Here, we examine the role of SES on brain structure using Mendelian randomisation. First, we conduct a multivariate genome-wide association study of SES using …

gb, it, nl, kr (code pays fourni par la source)

Author response for "Polygenic Associations With Educational Attainment in East Versus West Germany: Differences Emerge After Reunification"

Deniz Fraemke, Yayouk Eva Willems, Aysu Okbay, Ulman Lindenberger et autres

Advancing and Supporting FAIR Principle Adoption through Innovative Social Infrastructure Tools

Leonie Raijmakers, Edvard Hübinette, Elianna DeSota, Sina Iman et autres

The adoption of the FAIR data principles has revolutionised data management in Earth System Sciences (ESS), yet challenges persist in achieving true machine-actionability and comprehensive implementation. DeSci Labs introduces two innovative tools—Decentralised Persistent Identifiers (DPIDs) and the CODEX protocol—to address the barriers …

Author response for "Polygenic Associations With Educational Attainment in East Versus West Germany: Differences Emerge After Reunification"

Deniz Fraemke, Yayouk Eva Willems, Aysu Okbay, Ulman Lindenberger et autres