Shahin Bonakdar

A cell-laden methacrylated chitosan-based photocrosslinkable hydrogel for bone tissue engineering and its in vitro structural and biological characterization

Saeed Samani, Abolfazl Nazbar, Mohammad Vasei, Shahin Bonakdar et autres

The treatment of extensive bone defects involves the use of multicomponent scaffolds where different components can be precisely controlled according to specific conditions. Therefore, hybridizing biomaterials within cell-laden osteogenic bioscaffolds provides promising opportunities for clinical applications. In this study, a cell-laden, photocrosslinkable …

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Investigation of nanoscale topography and biomechanical tuning of PDMS substrates to enhance cardiomyocyte differentiation from human induced pluripotent stem cells

Fatemeh Etezadi, Mohammad Ali Shokrgozar, Shahin Bonakdar, Kentaro Hayashi et autres

PDMS is still the most widely used biomaterial for bioengineering studies, which can mimic the tissue stiffness and micro/nanostructure to improve the generation and investigation of iCM differentiation from hiPSCs.

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Breast Cancer-Mimetic Topographies Shape Mesenchymal Stem Cell Responses

Arian Ansardamavandi, Fatemeh Nili, Abolfazl Nazbar, Shahram Azari et autres

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Cell-imprinted substrates as biomimetic platforms for osteoarthritis modeling with mesenchymal stem cells

Hanieh Sadat Hashemi Motahar, Mojtaba Tajbakhsh, Mahboobeh Tavassoli, Shahin Bonakdar et autres

Introduction: The objective of this study is twofold: first, to investigate the relationship between chondrocyte morphology and their own gene and protein expression profiles in healthy and osteoarthritic (OA) cartilage; and second, to assess whether replicating the morphology of OA chondrocytes (OACs) …

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Wound healing improvement by a multicomponent wound dressing of keratinocyte-imprinted polydimethylsiloxane substrate in a rabbit model

Davoud Shams, Saeed Samani, Soheila Pourkhodadad, Setayesh Yasami‐Khiabani et autres

Wound healing is a major clinical challenge and regenerative medicine and tissue engineering suggest new ways to overcome such problems. The cell imprinting method can provide cues that regulate cell function or modulate stem cell differentiation into different lineages. In this study, …

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Chondrogenesis and Regulating Inflammatory Gene Expression

Parisa Madani, Sara Derhanbakhsh, Nasrin Salehi, Farzaneh Safshekan et autres

Due to the limitations of using primary chondrocytes, directing stem cells toward chondrogenesis via physical cues has emerged as an efficient strategy for cartilage regeneration. Substrate topography can strongly influence cellular behavior, including differentiation. Here, we investigated the effect of chondrocyte-imprinted substrates …

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Hydroxyapatite-induced bioactive and cell-imprinted polydimethylsiloxane surface to accelerate osteoblast proliferation and differentiation: an in vitro study on preparation and differentiating capacity

Morteza Mehrjoo, Akbar Karkhaneh, Masoumeh Haghbin Nazarpak, Mostafa Alishahi et autres

Healing bone defects remains a significant orthopedic challenge. Cell therapy and tissue engineering offer promising solutions; however, obtaining high-quality, partially or fully differentiated cells remains difficult. Therefore, developing suitable substrates to guide stem cell differentiation helps in achieving this goal. Here, an …

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Integrin Targeting: An Intelligent Approach in Articular Cartilage Tissue Engineering

Mohammad Tollabi, Zahra Poursalehi, Fatemeh Eskandari, Soheila Naderi Gharahgheshlagh et autres

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Author response for "The Regenerative Capacity of Cell Imprinting and Collagen/PCL Scaffold in Gastrocnemius Tendon Defect"

Seyed Aliakbar Hosseini Toopghara, Shahin Bonakdar, Sara Nayyeri, Morteza Mehrjoo et autres

Cell Imprint‐Mediated Differentiation of Adipose‐Derived Stem Cells Into Keratinocytes Enhances Wound Healing on Collagen‐Based Scaffolds: An Ovine Model Study

Mahdokht Khanamooei, Seyed Mehdi Ghamsari, Shahin Bonakdar, Hossein Aminianfar et autres

Full-thickness skin wound management remains a significant clinical challenge, necessitating innovative approaches that combine cellular therapy with biomaterial scaffolds. One of the promising approaches in regenerative medicine is the recellularisation of wound dressings. A polydimethylsiloxane (PDMS) substrate imprinted with ovine foetal keratinocytes …

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Interfacing with the Brain: How Nanotechnology Can Contribute

Abdullah Ahmed Ali Ahmed, Núria Alegret, Bethany Almeida, Ramón A. Álvarez‐Puebla et autres

Interfacing artificial devices with the human brain is the central goal of neurotechnology. Yet, our imaginations are often limited by currently available paradigms and technologies. Suggestions for brain-machine interfaces have changed over time, along with the available technology. Mechanical levers and cable …

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Corrigendum to “Macroporous scaffold surface modified with biological macromolecules and piroxicam-loaded gelatin nanofibers toward meniscus cartilage repair” [Int. J. Biol. Macromol. Volume 183(2021), Pages 1327–1345]

Zahra Abpeikar, Moosa Javdani, Seyed Abbas Mirzaei, Akram Alizadeh et autres

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