Fang Yuan

Genetic Diversity and Differentiation Pattern of Mastacembelus armatus in the Dongjiang and Ganjiang River Sources

Bin Wu, Fang Yuan, Qingxiang Zeng, Han Li et autres

To explore the genetic diversity and evolutionary differentiation of Mastacembelus armatus from the headwaters of the Dongjiang and Ganjiang Rivers, we performed whole-genome resequencing on three populations, including Xunyushui (XW) and Jiuqu River (DN) from the Dongjiang River source as well as …

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The concentration-, pH- and temperature-responsive self-assembly of undenatured type II collagen: kinetics, thermodynamics, nanostructure and molecular mechanism

Yuan Wang, Liang Zhang, Wenyan Liao, Zhen Tong et autres

In this work, the undenatured type II collagen (C-II) with an intact triple helix structure was obtained from chicken breast cartilage by the enzymatic extraction method. The self-assembly kinetics of C-II at different parameters of concentration, pH and temperature was characterized by …

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Corrigendum to “The concentration-, pH- and temperature-responsive self-assembly of undenatured type II collagen: Kinetics, thermodynamics, nanostructure and molecular mechanism” [Food Hydrocolloids 137, (April 2023), 108424]

Yuan Wang, Liang Zhang, Wenyan Liao, Zhen Tong et autres

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Influencing factors of flexion contracture among patients with knee osteoarthritis: a multi-center retrospective cross-sectional study

Jun Zhou, Yuanyuan Li, Xiaoyu Liu, Ping Wang et autres

Knee osteoarthritis (KOA) is a chronic disease with a high prevalence and disability rate. Alterations in lower limb alignment and reduction in lower limb muscle strength are important factors in the progression of KOA. Although pain is the main reason for KOA …

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Fire needling acupuncture attenuates synovial inflammation and cartilage degeneration in knee osteoarthritis via SDF-1/CXCR4-mediated macrophage polarization

Jiangyan Wei, Xin Nian Yang, Luopeng Zhao, Xueyan Liu et autres

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Research trends and hotspots of acupuncture for knee osteoarthritis from 2004 to 2024: a bibliometric analysis

Jun Zhou, Kuayue Zhang, Xueyan Liu, Fang Yuan et autres

Background Knee osteoarthritis (KOA) is a leading cause of pain and disability worldwide. Acupuncture has emerged as a prominent non-pharmacological treatment for KOA. This study aims to analyze the general research status, hotspots, and trends of acupuncture in the treatment of KOA. …

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Therapeutic Effects of Fire Needling Acupuncture on Pain Relief and Cartilage Protection in MIA-Induced Knee Osteoarthritis Rats: The Role of Macrophage Polarization in Synovium and Angiogenesis in Subchondral Bone

Jiangyan Wei, Xin Yang, Luopeng Zhao, Xueyan Liu et autres

Purpose: Knee osteoarthritis (KOA) is a prevalent degenerative disease impacting bone and joint health. Clinical studies indicate that fire needling acupuncture can alleviate joint stiffness, pain, and dysfunction in KOA. Previous research demonstrated its efficacy in reducing pain, mitigating cartilage damage, and …

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Significant enhancement of the thermal stability and catalytic efficiency of transglutaminase in Streptomyces mobaraensis engineered through the novel S. mobaraensis genomic mutant library construction method GHR/Sml

Fang Yuan, Guoying Li, Zilong Li, Mingming Li et autres

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LexA, an SOS response repressor, activates TGase synthesis in Streptomyces mobaraensis

Xinyu Shi, Hao Yan, Fang Yuan, Guoying Li et autres

Transglutaminase (EC 2.3.2.13, TGase), an enzyme that catalyzes the formation of covalent cross-links between protein or peptide molecules, plays a critical role in commercial food processing, medicine, and textiles. TGase from Streptomyces is the sole commercial enzyme preparation for cross-linking proteins. In …

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Role of ε-Poly-lysine in mixed surimi gel: concentration, underlying mechanism, and application

Zhaorui Li, Guangcan Liang, Yungang Cao, Fang Yuan et autres

The effects of different concentrations of ε-Poly-lysine (ε-PL: 0.005%, 0.01%, 0.02%, 0.04%, and 0.06%) on the marine fish-egg white protein compound gels, treated with 0.4% TGase induced cross-linking were systematically investigated under low salt and phosphorus-free conditions (0.5% NaCl). The results showed …

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Efficient biosynthesis of transglutaminase in Streptomyces mobaraensis via systematic engineering strategies

Fang Yuan, Guoying Li, Zilong Li, Mingming Li et autres

Transglutaminases (TGases) have been widely used in food, pharmaceutical, biotechnology, and other industries because of their ability to catalyze deamidation, acyl transfer, and crosslinking reactions between Ƴ-carboxamide groups of peptides or protein-bound glutamine and the Ɛ-amino group of lysine. In this study, …

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Insight into the composite assembly process, nanofibril structure and stability of undenatured type II collagen in the presence of different types of nanocelluloses

Yuan Wang, Liang Zhang, Like Mao, Fang Yuan et autres

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