Jun He

Strain-Controlled Polar-Ion Displacement Unlocks Reconfigurable Second-Harmonic Generation in van der Waals CuCrP2S6

Xian Zhang, Shikun Hou, Siyu Zhang, Junying Chen et autres

Abstract Two-dimensional van der Waals multiferroics offer a low-dimensional platform for tuning nonlinear optical responses through lattice distortion and polar symmetry. Yet translating polar-ion displacement into strong and tunable macroscopic second-harmonic generation (SHG) remains challenging as limited ionic off-centering and interlayer cancellation …

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Genetic pleiotropy differentially linking brain variation to cannabis use and cannabis use disorder

Qianyu Chen, Jun He, Dan Qiu, Ziang Xu et autres

Since cannabis use (CU) has increased substantially worldwide, understanding the neurobiological mechanisms differentiating CU from cannabis use disorder (CUD) has important public health implications. Leveraging genome-wide data available from UK Biobank, International Cannabis Consortium, the Psychiatric Genomics Consortium, and the Million Veteran …

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Ultrasound‐Driven Dual Piezocatalytic–Electrical Scaffold Synergistically Promotes Osteoporotic Bone Healing

Bing Tan, JianYuan Ouyang, Yanbo Wen, Li Ren et autres

ABSTRACT The regeneration of osteoporotic bone defects is severely hampered by compromised endogenous healing capacity, demanding advanced strategies that actively orchestrate pro‐osteogenic microenvironments. Here, we report an integrated, self‐powered osteo‐regenerative system that uniquely leverages a dual ultrasound‐responsive piezoelectric mechanism for synergistic therapy. …

cn (code pays fourni par la source)

Surgical outcomes of indocyanine green fluorescent cholangiography in emergency laparoscopic cholecystectomy performed by junior surgeons for acute cholecystitis

Lei Gao, Jun He, Yifeng Qian, Fei Yuan et autres

Background: Emergency laparoscopic cholecystectomy (LC) remains the preferred treatment for acute cholecystitis (AC); however, the prevalence of complications and negative outcomes increases in these emergency surgeries, especially when performed by junior surgeons. Recently, indocyanine green (ICG) fluorescent cholangiography has emerged as a …

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Bone Density Contributes to Lumbar Disc Herniation: A Mendelian Randomization Study

Temitope M. Adegbenro, Jun He, Renato Polimanti, Konstantinos Margetis

Study Design: Genetic epidemiology study integrating two-sample univariable and multivariable Mendelian randomization (MR), with observational triangulation in UK Biobank. Objective: To determine whether lifelong liability to higher bone mineral density (BMD) causally increases risk of lumbar disc herniation (LDH), evaluate reverse causation …

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Case report: A case of benign uterine leiomyoma with intense 18F-FDG uptake mimicking malignant tumor on PET/CT

Taiping Liao, Guoxu Fu, Yongjun Long, Songsong Yang et autres

Uterine leiomyoma is a common benign tumor of the uterus and typically demonstrates low FDG uptake on 18 F-FDG PET/CT. Intense FDG uptake in a uterine mass is generally considered suggestive of malignancy. Here, we report a case of uterine leiomyoma in …

cn (code pays fourni par la source)

Multi-ancestry genome-wide association and integrated multi-omics analyses of endometriosis and its clinical manifestations

Dóra Koller, Jun He, Solveig Løkhammer, Selena Aranda et autres

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Multivariate genome-wide association study of suicidal behaviors in >1.7 million individuals of diverse population descents

Jun He, Brenda Cabrera‐Mendoza, Dan Qiu, David Davtian et autres

Summary Background While previous genome-wide association studies (GWAS) identified multiple risk loci for suicide ideation (SI) and suicide attempt (SA), there is still a limited understanding of the genetic predisposition underlying suicidal behaviors in diverse populations. This study aimed to conduct a …

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The effect of cumulative exposure to unhealthy behavioral lifestyles on incident primary dyslipidemia: a prospective study from the Chinese government employee cohort

Ling Li, Yilu Li, Chengcheng Zhang, Jun He et autres

BACKGROUND: While specific unhealthy behavioral lifestyles link to primary dyslipidemia (PD), cumulative effects remain unknown. We quantified the association with incidence of PD with cumulative exposure clustering of lifestyles. METHODS: Eleven thousand eight hundred forty-three government staff enrolled (2018–2020) and followed (2019–2021). …

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DEHP induces hepatic fibrosis through STAT3-SLC7A11-ROS axis

Zhiliang Xu, Xiaoxiang You, Tinghao Yuan, Jun He et autres

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Analysis of the risk of metachronous colorectal cancer and long-term prognosis in patients following gastrectomy for gastric cancer

Jun He, Bixian Luo, Changyun Liu, Dong Cao et autres

The impact of gastrectomy on the risk of developing second colorectal cancer (SCRC) in gastric cancer patients remains unclear. This study aimed to evaluate the association between gastrectomy and SCRC in gastric cancer patients. A total of 17,606 patients with gastric cancer …

cn (code pays fourni par la source)

Association between carotene intake and hospital-acquired pneumonia in elderly men: a cross-sectional study

Jun He, Boyang Wei, Xue-Geng Hong, Yan Gao

BACKGROUND: Elderly inpatients are at high risk for hospital-acquired pneumonia (HAP). The association between dietary carotene and HAP remains unclear. METHODS: This cross-sectional study included 165 patients aged ≥ 80 years. Dietary carotene intake was assessed via 72-hour recall and food weighing, …

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