2025
article
OpenAlex
Parisa Azimisefat, Parisa Glass, Philipp Kanske, Philipp Herzog
Community trauma refers to the psychological and social impact collectively experienced by a group following prolonged adversity or traumatic events, such as natural disasters, violent acts, or major accidents. In Iran, recent instances of community trauma include the violent repression of protests …
ir, au, de
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Accès ouvert
2023
article
OpenAlex
Paul Jeffrey Young, Anthony Devaux, Qiang Li, Laurent Billot et autres
nz, au, gb, in
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2022
article
OpenAlex
Catherine Boschert, Emma Broadfield, Timothy Chimunda, Jason Fletcher et autres
Importance: Whether selective decontamination of the digestive tract (SDD) reduces mortality in critically ill patients remains uncertain. Objective: To determine whether SDD reduces in-hospital mortality in critically ill adults. Design, Setting, and Participants: A cluster, crossover, randomized clinical trial that recruited 5982 …
au
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Accès ouvert
2021
article
OpenAlex
Laurent Billot, Brian H. Cuthbertson, Anthony C. Gordon, Farah Al-Beidh et autres
ABSTRACT Background: It is unclear whether the use of selective decontamination of the digestive tract (SDD) improves outcomes in ventilated patients in intensive care units (ICUs) and whether SDD is associated with the development of antibiotic resistance . Objective: To describe the …
au, ca, gb, nz
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Accès ouvert
2019
article
OpenAlex
Naomi E. Hammond, Rinaldo Bellomo, Martin Gallagher, David J. Gattas et autres
au, nz
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Accès ouvert
2019
article
OpenAlex
Balasubramanian Venkatesh, Simon R. Finfer, Jeremy Cohen, Dorrilyn Rajbhandari et autres
BACKGROUND: Two recent randomized controlled trials (Adjunctive Glucocorticoid Therapy in Patients with Septic Shock [ADRENAL] and Activated Protein C and Corticosteroids for Human Septic Shock [APROCCHSS]) of corticosteroids in patients with septic shock reported different treatment effects on 90-day mortality. Both trials …
us, ar, au, in, gb
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Accès ouvert
2019
article
OpenAlex
Paula Muñoz Venturelli, Xian Li, Sandy Middleton, Caroline Leigh Watkins et autres
Background The uptake of proven stroke treatments varies widely. We aimed to determine the association of evidence-based processes of care for acute ischemic stroke ( AIS ) and clinical outcome of patients who participated in the HEADPOST (Head Positioning in Acute Stroke …
cl, au, cn, gb, br, jp
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2019
article
OpenAlex
Jeffrey Lipman, Stephen James Brett, Jan J. De Waele, Menino Osbert Cotta et autres
BACKGROUND AND RATIONALE: β-Lactam antibiotics display a time-dependent mechanism of action, with evidence suggesting improved outcomes when administering these drugs via continuous infusion compared with standard intermittent infusion. However, there is no phase 3 randomised controlled trial (RCT) evidence to support one …
au, gb, be, nz
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2019
article
OpenAlex
Yining Huang, Richard I. Lindley, Xiaoying Chen, Hisatomi Arima et autres
cn, au, jp, gb, us, ca, cl, tw, br, in, it, sg, vn
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2018
article
OpenAlex
Balasubramanian Venkatesh, Simon R. Finfer, Jeremy Cohen, Dorrilyn Rajbhandari et autres
Sepsis has been identified by the WHO as a global health priority, however, there has been no proven pharmacologic treatment other than the appropriate antibiotic agents, fluids and vasopressors as required. Reported death rates among hospitalized patients with sepsis range between 30-45% …
Accès ouvert
2018
article
OpenAlex
Balasubramanian Venkatesh, Simon R. Finfer, Jeremy Cohen, Dorrilyn Rajbhandari et autres
BACKGROUND: Whether hydrocortisone reduces mortality among patients with septic shock is unclear. METHODS: We randomly assigned patients with septic shock who were undergoing mechanical ventilation to receive hydrocortisone (at a dose of 200 mg per day) or placebo for 7 days or …
au, sa, vn, nz, dk, gb, in
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Accès ouvert
2017
article
OpenAlex
Naomi E. Hammond, Rinaldo Bellomo, Martin Gallagher, David J. Gattas et autres
BACKGROUND: 0.9% sodium chloride (saline) is the most commonly administered resuscitation fluid on a global basis but emerging evidence suggests that its high chloride content may have important adverse effects. OBJECTIVE: To describe the study protocol for the Plasma- Lyte 148 v …
au, nz
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