Khaled Shelbaya

Alterations in Cardiac Structure and Function Associated With Sub‐Severe Aortic Stenosis Progression: The ARIC Study

Khaled Shelbaya, Brian Claggett, Pranav Dorbala, Hicham Skali et autres

Background American Heart Association and American College of Cardiology guidelines articulate 4 aortic stenosis ( AS ) stages to highlight its progressive nature, but limited data exist on cardiac alterations in sub‐severe stages. Methods ARIC (Atherosclerosis Risk in Communities) study participants with …

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Abstract 4366441: The association between smoking and albuminuria in a population with a substantial burden of cardiovascular disease

Bassem Zarif, Victor Fadlallah Francis, Mahmoud Maher, Basheer Hafez et autres

Background: According to the global burden of cardiovascular diseases (CVD), Egypt experiences one of the highest CVD-related mortalities. Albuminuria is recognized as a risk marker for CVD and is associated with smoking. However, the association between smoking and albuminuria is understudied in …

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Abstract 4370397: Prognosis of Cardiovascular-Kidney-Metabolic (CKM) Stages: The Dallas Heart Study

Khaled Shelbaya, Yimin Yang, Victoria Lamberson, Yinun Zeleke et autres

Background: The recent AHA presidential advisory on Cardiovascular-Kidney-Metabolic Syndrome (CKM) proposed a novel staging scheme, but limited data exist regarding the associations of CKM Stages with incident cardiovascular events and mortality. Methods: We included participants in the Dallas Heart Study, a population-sampled …

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Abstract 4368885: Progression in Cardiovascular-Kidney-Metabolic (CKM) Stages Over 7 Years in Mid-Life: The Dallas Heart Study

Khaled Shelbaya, Yimin Yang, Yinun Zeleke, Victoria Lamberson et autres

Introduction: While previous studies have quantified the community prevalence of Cardiovascular-Kidney-Metabolic (CKM) Stages, limited data exist regarding the expected progression of CKM Stages in mid-life. Methods: Among participants in the population-sampled Dallas Heart Study (DHS) longitudinal cohort, we estimated the prevalence of …

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Association of Left Atrial Function With Mitral Regurgitation: The Atherosclerosis Risk in Communities Study

Chunxiao Zhang, Wendy Wang, Riccardo Maria Inciardi, Yuekai Ji et autres

BACKGROUND: Lower left atrial (LA) function may precede LA enlargement and contribute to mitral regurgitation (MR). We examined the association of LA reservoir strain (a measure of LA function) with MR in the ARIC (Atherosclerosis Risk in Communities) study. METHODS: We analyzed …

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ALBUMINURIA SCREENING AMONG EGYPTIAN PATIENTS WITH CARDIOVASCULAR DISEASES REGARDLESS OF THEIR DIABETIC CONDITION

Khaled Shelbaya, Baher Emil, Basheer Hafez, Mahmoud Maher et autres

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Abstract MP35: Community Prevalence of the Cardiovascular-Kidney-Metabolic (CKM) Syndrome: The Dallas Heart Study

Khaled Shelbaya, Yinun Zeleke, Victoria Lamberson, Yimin Yang et autres

Introduction: The recent AHA presidential advisory on Cardiovascular-Kidney-Metabolic Syndrome (CKM) proposed a novel staging scheme, but limited data exist regarding CKM stage prevalence in the community. Prior population-based studies have lacked subclinical imaging measures, and have not reported variability by age, gender, …

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Exploring the effects of hemodialyzers on clinical outcomes in pediatric cardiac surgery during cardiopulmonary bypass: a retrospective cohort study

Ahmed M. Abdelazim, Akram Mohamed Amer, Yasmin Elsobky, Khaled Shelbaya et autres

Abstract Background Hemofiltration during and after cardiopulmonary bypass (CPB) reduces levels of proinflammatory cytokines and total interstitial body water. Because of economic causes, hemofilters became less available in low- and middle-income countries, which forced the perfusionists to use hemodialyzers instead. This study …

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Abstract 4141779: Metabolomic Markers of Aortic Stenosis Development: the Atherosclerosis Risk in Communities (ARIC) Study

Khaled Shelbaya, Victoria Lamberson, Yimin Yang, Taryn Alkis et autres

Background: Prior metabolomics studies in aortic stenosis (AS) have focused on patients with severe stenosis and their response to intervention. Limited data exist regarding circulating metabolites predictive of AS development. Aim: Identify circulating metabolites associated with aortic valve (AV) hemodynamics and incident …

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Validation of angiography-derived Murray law-based quantitative flow reserve (μQFR) against pressure-derived instantaneous wave-free ratio for assessing coronary lesions, a single-center study in Egypt

Amir Anwar Samaan, Amir Ismail Ibrahim Abo Mostafa, Sherif Lotfy Wahba, Matteo Kerlos et autres

BACKGROUND: Instantaneous wave-free ratio (iwFR) is a well-validated method for functional evaluation of intermediate coronary lesions. A recently developed Murray law-based QFR (µQFR) allows wire-free FFR estimation using a high-quality single angiographic projection. We aim to determine the diagnostic accuracy of µQFR …

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Distribution of cardiovascular risk severity among Egyptian patients with established cardiovascular diseases

Victor Fadlallah Francis, Saed Elshamy, Ahmed Mahgoub, Khaled Shelbaya et autres

Abstract Background The Secondary Manifestations of Arterial Disease (SMART) risk score was recommended by the European Society of Cardiology (ESC) to estimate a 10-year risk for myocardial infarction, stroke, or vascular death in individual patients with clinically manifested atherosclerotic vascular disease (ASCVD).(1) …

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PREDICTIVE ROLE OF EXTRA-AORTIC VALVE ABNORMALITIES IN SUB-SEVERE AORTIC STENOSIS: THE ATHEROSCLEROSIS RISK IN COMMUNITIES (ARIC) STUDY

Khaled Shelbaya, Brian Lee Claggett, Hicham Skali, Pranav Dorbala et autres

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