Yue Yang

Molecular mechanisms of bacteria-mediated cancer immunotherapy: from intratumoral microbiota to engineered therapeutics

Guo Jinhu, Yimeng Li, Yue Yang, Bobo Wang

Immunotherapy has redefined oncology, yet its efficacy remains constrained by low response rates, primary or acquired resistance, immune-related toxicities, and escalating costs. Bacteria-mediated cancer immunotherapy (BCIT), which exploits the intratumoral microbiota as a programmable immunotherapeutic platform, has therefore emerged as a promising …

cn (code pays fourni par la source)

SLFN5 influences proliferation and apoptosis by upregulating PTEN transcription via ZEB1 and inhibits the purine metabolic pathway in breast cancer: Am J Cancer Res. 2020; 10(9): 2832-2850

Xuefeng Gu, Guoqing Wan, Yue Yang, Yihao Liu et autres

Human Schlafen-5 (SLFN5) is aberrantly involved in tumorigenesis in several types of cancer. However, its implications in breast cancer (BRCA) are unknown. Herein, we demonstrated that SLFN5 expression is negatively associated with the tumour growth of human BRCA using GEO database analysis …

cn (code pays fourni par la source)

Low-dose simvastatin protects pancreatic cancer cells by promoting mitochondrial autophagy through TFEB

Zhiliang Wang, Di Wu, Yue Zhang, Weibo Chen et autres

cn (code pays fourni par la source)

Expression Of Wnt3a In Dfs And Cells During Osteogenic Differentiation

Yan Liu, Lusai Xiang, Yue Yang, Junqi Ling et autres

To investigate the expression of Wnt3a in rat dental follicle tissues and the expression of Wnt3a in the process of osteogenic differentiation of dental follicle cells, so as to explore the role of Wnt3a in the osteogenic differentiation of dental follicle cells. …

cn (code pays fourni par la source)

An In Vitro BRAF Activation Assay Elucidates Molecular Mechanisms Driving Disassembly of the Autoinhibited BRAF State

Daniel A. Ritt, David Durrant, Matthew Drew, Juliana A. Martinez Fiesco et autres

Abstract The RAF kinases (ARAF, BRAF and CRAF) are essential components of the RAS-ERK signaling pathway, which controls vital cellular processes and is frequently dysregulated in human disease. Notably, mutations that alter BRAF function are prominent drivers of human cancer and certain …

us, my (code pays fourni par la source)

Effects of Mindfulness Intervention on Cognitive Function in Athletes: A Systematic Review and Meta-Analysis

Yue Yang, Xiru Du, Xinyu Liu, Peilun Li et autres

As the application of mindfulness interventions (MIs) continues to grow, its utility extends beyond mental health treatment, showing cognitive benefits for athletes, including increased focus, reduced distractions, and enhanced task efficiency. The integration of MI into cognitive neuroscience has practical implications for …

cn, mo (code pays fourni par la source)

Development of B-to-A base editors by leveraging translesion synthesis polymerase

Puping Liang, Pengfei Zhang, Yuxi Chen, Weijun Zhao et autres

cn, fr (code pays fourni par la source)

Fourth-generation EGFR-TKI to overcome C797S mutation: past, present, and future

Die Zhang, Jumei Zhao, Yue Yang, Qiangfang Dai et autres

Overactivation of the epidermal growth factor receptor (EGFR) is prevalent in various tumours, rendering it a promising target for cancer therapy, particularly in the treatment of non-small cell lung cancer (NSCLC). Although the first through third generations of EGFR tyrosine kinase inhibitors …

cn (code pays fourni par la source)

Multiomics analysis elucidated the role of inflammatory response and bile acid metabolism disturbance in electric shock-induced liver injury in mice

Wenjuan Zhang, Hui Wang, C. N. H. Long, Jin Liu et autres

PURPOSE: Organ damage caused by electric shock has attracted great attention. Some animal investigations and clinical cases have suggested that electric shock can induce liver injury. This study aimed to investigate the potential mechanism of liver injury induced by electric shock. METHODS: …

cn, sa (code pays fourni par la source)

Simvastatin protects pancreatic cancer cells by promoting mitochondrial autophagy through TFEB

Zhiliang Wang, Di Wu, Yue Zhang, Weibo Chen et autres

cn (code pays fourni par la source)

Construction of circRNA–miRNA–mRNA ceRNA regulatory network and screening of diagnostic targets for tuberculosis

Xinyi Pu, Siyu Sheng, Yujuan Fu, Yue Yang et autres

), which threatens human health and safety all over the world. Hundreds of thousands of people die from TB every year. Timely early diagnosis and treatment of patients is the most important measure to control the source of infection and curb the …

cn (code pays fourni par la source)

IL15RA-STAT3-GPX4/ACSL3 signaling leads to ferroptosis resistance in pancreatic cancer

Di Wu, Zhiliang Wang, Yue Zhang, Yang Yang et autres

Pancreatic ductal adenocarcinoma (PDAC) is a highly malignant disease with a poor prognosis, and the lack of effective treatment methods accounts for its high mortality. Pancreatic stellate cells (PSCs) in the tumor microenvironment play an important role in the development of PDAC. …

cn (code pays fourni par la source)