T. Scase

Histopathological frequency of canine hepatobiliary disease in the United Kingdom

Y. M. S. P. Y. Bandara, W. A. Bayton, Tim Williams, T. Scase et autres

OBJECTIVES: Canine hepatobiliary disease is common; however, data determining disease frequency and breed predispositions are lacking. The primary objective was to identify the frequency of different hepatobiliary disease in a United Kingdom population of dogs and consequently determine breeds at both an …

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Chronic Inflammatory Disease in the Pancreas, Kidney and Salivary Glands of English Cocker Spaniels and Dogs of Other Breeds Shows Similar Histological Features to Human IgG4-related Disease

M. Francisca Coddou, Fernando Constantino‐Casas, T. Scase, Michael Day et autres

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A Novel Hepadnavirus is Associated with Chronic Hepatitis and Hepatocellular Carcinoma in Cats

Patricia A. Pesavento, Kenneth A. Jackson, T. Scase, Tiffany Tse et autres

In 2015, over 850,000 people died from chronic hepatitis and hepatocellular carcinoma (HCC) caused by hepatitis B virus (HBV). A novel hepatitis B-like virus has recently been identified in domestic cats. The pathogenic potential of domestic cat hepadnavirus (DCH), for which 6.5% …

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Altered Nuclear Expression of the Deubiquitylase BAP1 Cannot be Used as a Prognostic Marker for Canine Melanoma

Nimo Jama, Neil Farquhar, Zohra Butt, Sarah E. Coupland et autres

BRCA1-associated protein-1 (BAP1) is a nuclear localized deubiquitylating enzyme that belongs to the ubiquitin c-terminal hydrolase subfamily. The encoded protein is highly homologous between man and dogs, suggesting a functional significance preserved by evolution. BAP1 has multiple properties, including tumour suppressor activity. …

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PetSavers research

Elspeth Milne, Yolanda Martínez Pereira, C. S. Muir, T. Scase et autres

Abstract Immunohistochemical differentiation of reactive from malignant mesothelial cells as a diagnostic aid in canine pericardial disease.

Immunohistochemical differentiation of reactive from malignant mesothelium as a diagnostic aid in canine pericardial disease

Elspeth Milne, Yolanda Martínez Pereira, C. S. Muir, T. Scase et autres

OBJECTIVES: To develop a provisional immunohistochemistry panel for distinguishing reactive pericardium, atypical mesothelial proliferation and mesothelioma in dogs. MATERIALS AND METHODS: Archived pericardial biopsies were subject to haematoxylin and eosin staining, immunohistochemistry for cytokeratin, vimentin, insulin-like growth factor II mRNA-binding protein 3, …

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How to make a diagnosis

T. Scase, Jane Dobson

Obtaining an accurate pathological diagnosis is an essential requirement for optimizing the treatment of the individual cancer patient and for providing the client with an assessment of likely cancer behaviour and likely prognosis. This chapter deals with cytology; surgical biopsy techniques; submission …

Canine Clitoral Carcinoma: A Clinical, Cytologic, Histopathologic, Immunohistochemical, and Ultrastructural Study

Ranieri Verin, Francesco Cian, Jennifer Stewart, Diana Binanti et autres

Vaginal and vulvar tumors are uncommon in dogs. Knowledge of canine primary clitoral neoplasia is restricted to a few case reports, and only carcinomas have been reported. Cytologic and histologic features reported in the literature seem to overlap with those of canine …

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Histopathological frequency of feline hepatobiliary disease in the UK

W. A. Bayton, Charlotte Westgarth, T. Scase, David J. Price et autres

OBJECTIVES: To determine the histopathological frequency of feline hepatobiliary diseases in the UK and to identify breed, age and gender predispositions to developing individual diseases. METHODS: Histopathology results from 1452 feline liver biopsies were assessed. A control population of microchipped cats was …

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Pathological and Clinical Features of Canine Clitoral Carcinoma

Ranieri Verin, Francesco Cian, Jennifer Stewart, Diana Binanti et autres

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Expression of VEGFR and PDGFR-alpha/-beta in 187 canine nasal carcinomas

Irina Gramer, David Killick, T. Scase, D. Chandry et autres

Use of neutrophil to lymphocyte ratio for predicting histopathological grade of canine mast cell tumours

Michael Macfarlane, Laura Macfarlane, T. Scase, Tim Parkin et autres

Canine mast cell tumours (MCTs) are variable in their biological behaviour and treatment decisions depend heavily on the histopathological grade. Biomarkers such as neutrophil to lymphocyte ratio (NLR) and albumin to globulin ratio are used to predict the biological behaviour of human …

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