Tomás Salas

Leisure‐Time Physical Activity on Age‐Modelled Trajectories of Body Mass Index and Obesity Risk Throughout Life: Multivariable Regression and Mendelian Randomization Analyses Using Electronic Health Record Data From the CORDELIA ‐Catalunya Study

Javier Hernando‐Redondo, Anna Camps‐Vilaró, Roberto Elosua, Eleonora Fornara et autres

ABSTRACT Aims To assess whether self‐reported leisure‐time physical activity, moderate‐to‐vigorous leisure‐time physical activity, and genetically determined cardiorespiratory fitness are associated with age‐related BMI trajectories and incident obesity. Methods We pooled 14 993 adults (30–90 years; 52.7% women; cohorts: REGICOR‐ACRISC, ILERVAS, ARTPER) with …

es (code pays fourni par la source)

Leisure-time physical activity on lifelong trajectories of body mass index and obesity risk throughout life: multivariable regression and Mendelian randomization analyses using real-world data from the CORDELIA-Catalunya Study

Javier Hernando Redondo, Anna Camps-Vilaró, Roberto Elosúa, Eleonora Fornara et autres

ABSTRACT Background Evidence on how leisure-time physical activity (LTPA) improves lifetime body mass index (BMI) remains fragmented and prone to confounding. Methods We pooled 14,993 adults (30-90 y; 52.7% women; cohorts: REGICOR-ACRISC, ILERVAS, ARTPER) with baseline estimated LTPA (moderate-to-vigorous LTPA [MVLTPA] in …

es (code pays fourni par la source)

ExCaPT: Explainable Cancer Prediction with Transformer-based models

Ditsuhi Iskandaryan, Ferrán Moratalla-Navarro, Alba Magallon-Baro, Lois Riobó‐Mayo et autres

Abstract Cancer remains one of the most significant global health challenges. De-spite advances in treatment, early detection remains a critical concern. The increasing availability of Electronic Health Records (EHR) offers a unique opportunity to enhance our understanding of patient health trajectories and …

es (code pays fourni par la source)

Early improvement on cardiac function and dyssynchrony after physiological upgrading in pacing-induced cardiomyopathy

E Amigo Otero, Tomás Salas, I M Esteve Ruiz, J M Carreno Lineros et autres

Abstract Background Interventricular dyssynchrony derived from the classic non-physiological stimulation (n-PS) of the right ventricle (RV) is a known cause of left ventricular dysfunction (LVDys). Methods This was a retrospective descriptive single-center study. We analyzed patients who develop LVDys with n-PS, and …

es (code pays fourni par la source)

#2277 Artificial Intelligence for predicting heart failure in chronic kidney disease: analysis of a 5000-patient cohort

José Ibeas, Oscar Galles, Remo Suppi, Jordi Comas et autres

Abstract Background and Aims Chronic kidney disease (CKD) and heart failure share a complex, bidirectional interaction, and are therefore an area of crucial interest in nephrology due to their prevalence and effect on mortality. It is basic to identify the risk of …

es (code pays fourni par la source)

Drug Repurposing for Cancers With Limited Survival: Protocol for a Retrospective Cohort Study

Alejandro Rodríguez‐Molinero, Carlos Pérez‐López, Jose L. Salazar González, Esther García-Lerma et autres

BACKGROUND: Only 5% of the molecules tested in oncology phase 1 trials reach the market after an average of 7.5 years of waiting and at a cost of tens of millions of dollars. To reduce the cost and shorten the time of …

es (code pays fourni par la source)

#4640 PREDICTION OF CHRONIC KIDNEY DISEASE PROGRESSSION WITH ARTIFICIAL INTELLIGENCE: A CHALLENGE WITHIN OUR REACH

Oscar Galles, Remo Suppi, Edwar Macias, Antoni Morell et autres

Abstract Background and Aims Chronic Kidney Disease (CKD) is a common and debilitating condition that affects over 850 million people worldwide. The disease is associated with high mortality rates that can reach up to 10-15% per year, multiple complications, among which cardiovascular …

es (code pays fourni par la source)

Drug Repurposing for Cancers With Limited Survival: Protocol for a Retrospective Cohort Study (Preprint)

Alejandro Rodríguez‐Molinero, Carlos Pérez‐López, Jose L. Salazar González, Esther García-Lerma et autres

BACKGROUND Only 5% of the molecules tested in oncology phase 1 trials reach the market after an average of 7.5 years of waiting and at a cost of tens of millions of dollars. To reduce the cost and shorten the time of …

Religiosidad popular: La fe en el espacio público

Tomás Salas

Nowadays, popular religiosity has an enormous importance throughout Spain, and especially in Andalusia. This situation contrasts with the process of secularization that, as in all Western societies, is taking place. Parting from this approach, we will analyzed this phenomenon within current Spanish …

El mal como principio primordial de la historia: notas a un cuento de Isaac Bashevis Singer

Tomás Salas

Un intelectual de la concordia: Julián Marías y su idea de la Corona

Tomás Salas

espanolEl sistema politico monarquico (la Corona) llega a Espana junto con la democracia. Supone un intento de superacion de la discordia historica que ha estado presente en Espana durante mucho tiempo. Julian Marias estudia la Monarquia espanola en varias obras. En este …

Change Management and Staff engagement processes. Lessons learned at ACT@Scale Project

Núria Rodríguez Valiente, Montse Moharra Francés, Tomás Salas, Cristina Bescos et autres

The International Journal of Integrated Care (IJIC) is an online, open-access, peer-reviewed scientific journal that publishes original articles in the field of integrated care on a continuous basis.IJIC has an Impact Factor of 5.120 (2020 JCR, received in June 2021)

es (code pays fourni par la source)