Frédérique Weber‐Lotfi

R-loop control and mitochondrial genome stability require the 5′-3′ exonuclease/flap endonuclease OEX1

Déborah Schatz, Anaïs Le Blevenec, Fabio Moratti, Kin Pan Chung et autres

Maintenance of the plant organelle genomes involves factors mostly inherited from their symbiotic ancestors. In bacteria, DNA polymerase I (Pol I) performs multiple replication and repair functions through its 5'-3'-exonuclease/flap-endonuclease domain. Plant organelles possess 2 DNA polymerases that are evolutionarily derived from …

fr, de (code pays fourni par la source)

R-Loop control and mitochondria genome stability require the 5’-3’ exonuclease/flap endonuclease OEX1

Déborah Schatz-Daas, Anaïs Le Blevenec, Fabio Moratti, Pierre Mercier et autres

Abstract Maintenance of the plant organelle genomes involves factors mostly inherited from their bacterial symbiotic ancestors. In bacteria, a major player in genome maintenance is DNA Polymerase I (Pol I), which provides a 5’-3’-exonuclease/flap-endonuclease activity required for multiple replication and repair functions. …

fr, de (code pays fourni par la source)

Mitochondrial DNA Isolation from Plants

Frédérique Weber‐Lotfi, Arnaud Fertet, Rokas Kubilinskas, Clémentine Wallet et autres

fr (code pays fourni par la source)

RADA-dependent branch migration has a predominant role in plant mitochondria and its defect leads to mtDNA instability and cell cycle arrest

Nicolas Chevigny, Frédérique Weber‐Lotfi, Anaïs Le Blevenec, Cédric Nadiras et autres

Mitochondria of flowering plants have large genomes whose structure and segregation are modulated by recombination activities. The post-synaptic late steps of mitochondrial DNA (mtDNA) recombination are still poorly characterized. Here we show that RADA, a plant ortholog of bacterial RadA/Sms, is an …

fr (code pays fourni par la source)

Plant mitochondria import DNA via alternative membrane complexes involving various VDAC isoforms

T. A. Tarasenko, Е. С. Клименко, В. И. Тарасенко, M. V. Koulintchenko et autres

ru, fr (code pays fourni par la source)

RADA is a main branch migration factor in plant mitochondrial recombination and its defect leads to mtDNA instability and cell cycle arrest

Nicolas Chevigny, Frédérique Weber‐Lotfi, Cédric Nadiras, Arnaud Fertet et autres

ABSTRACT The mitochondria of flowering plants have large and complex genomes whose structure and segregation are modulated by recombination activities. The late steps of mitochondrial recombination are still poorly characterized: while the loss of mitochondrial recombination is not viable, a deficiency in …

fr (code pays fourni par la source)

Mitochondrial Transcriptome Control and Intercompartment Cross-Talk During Plant Development

Adnan Khan Niazi, Étienne Delannoy, Rana Khalid Iqbal, Daria Mileshina et autres

We address here organellar genetic regulation and intercompartment genome coordination. We developed earlier a strategy relying on a tRNA-like shuttle to mediate import of nuclear transgene-encoded custom RNAs into mitochondria in plants. In the present work, we used this strategy to drive …

fr, pk, pl (code pays fourni par la source)

STUDYING OF DIFFERENT LENGTH AND STRUCTURE DNA IMPORT INTO PLANT MITOCHONDRIA

Yu. M. Konstantinov, Т.А. Болотова, André Dietrich, Frédérique Weber‐Lotfi et autres

3 Федеральное государственное бюджетное образовательное учреждение высшего образования «Иркутский государственный университет», Иркутск, Россия Аннотация.Изучены кинетика митохондриального импорта ДНК-субстратов 265 п.н., 2732 п.н.и 9 т.п.н, а также их конкурентные взаимотношения в процессе импорта в митохондрии клубней картофеля (Solanum tuberosum).Фланкирование субстрата импорта 9 т.п.н.концевыми …

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Targeting Therapeutic Nucleic Acids into Mitochondria: A Long Challenge

Frédérique Weber‐Lotfi, André Dietrich

fr (code pays fourni par la source)

Intercompartment RNA Trafficking in Mitochondrial Function and Communication

Frédérique Weber‐Lotfi, André Dietrich

fr (code pays fourni par la source)

DNA import into mitochondria

Yu. M. Konstantinov, Arthur Dietrich, Frédérique Weber‐Lotfi, Noha Ibrahim et autres

In recent decades, it has become evident that the condition for normal functioning of mitochondria in higher eukaryotes is the presence of membrane transport systems of macromolecules (proteins and nucleic acids). Natural competence of the mitochondria in plants, animals, and yeasts to …

ru, fr (code pays fourni par la source)

Nucleic acid import into mitochondria: New insights into the translocation pathways

Frédérique Weber‐Lotfi, M. V. Koulintchenko, Noha Ibrahim, Philippe Hammann et autres

fr, ru (code pays fourni par la source)