Patricia García

One Health Genomic Analysis of Methicillin‐Resistant Staphylococcus spp. From Humans, Cats, and Dogs in a Veterinary Hospital in Central Chile

Daniel Garrido, Danny Fuentes‐Castillo, Leslye Camila del Río, Jorge Barraza‐Schulmeyer et autres

INTRODUCTION: The emergence of methicillin-resistant Staphylococcus species (MRS) poses a growing threat to both human and veterinary health. METHODS: We performed a comparative genomic characterisation of 49 methicillin-resistant Staphylococcus isolates collected from humans, dogs, and cats in a veterinary hospital from Central …

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Activity of novel antibiotics against dual metallo-Beta-lactamase producing Enterobacter hormaechei clinical isolates

Camila Solar, Lorena Díaz, Katherine Soto, Jose R W Martínez et autres

Abstract Background Metallo-β-lactamase (MBL)-producing carbapenemase-resistant Enterobacterales infections are associated with significant mortality. Several β-lactam/β-lactamase inhibitor combinations (BL/BLI) with promising activity against MBLs are in the pipeline. Objective To investigate the in vitro activity of upcoming BL/BLI agents against Enterobacter hormaechei clinical isolates …

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An Algorithm for Rapid and Low-Cost Detection of Carbapenemases Directly from Positive Blood Cultures Using an Immunochromatographic Test

Patricia García, Pamela Rojas, Ana M Guzmán D, Aniela Wozniak

Background/Objectives: Detection of carbapenemases (KPC, OXA-48, VIM, IMP, NDM) from blood cultures (BCs) by standard methods takes 48–72 h and includes BC seeding, susceptibility testing and carbapenemase detection. Automated qPCR panels provide results in 1 h but are very costly. We aim …

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Window Prophylaxis for Mycobacterium tuberculosis Infection Prevention in Child and Adolescent Household Contacts: Study Protocol for a Cluster-Randomized Controlled Trial (the TB-WIN trial)

Nicole Le Corre, Kasim Allel, Mariluz Hernández, Nadia Escobar et autres

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Pseudomonas gelidaquae sp. nov., an Antarctic bacterium with a distinctive Type III Secretion System, isolated from Fildes Bay, King George Island

Sebastián Higuera‐Llantén, María Soledad Pavlov, Leandro Pio de Sousa, Felipe Vásquez‐Ponce et autres

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Reducing Household Tuberculosis Transmission: A Pilot Cluster-Randomized Controlled Trial

Cinthya Ruiz-Tagle, Romina Seguel, Luis Antonio Villarroel, Margarita Bernales et autres

BACKGROUND: The duration of infectiousness following pulmonary tuberculosis treatment initiation remains uncertain. We aimed to assess whether a bundled intervention designed to decrease respiratory exposure was feasible and would reduce new tuberculosis infections in household contacts (HHCs). METHODS: We conducted a pilot …

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A prospective, multicenter study of invasive fungal disease caused by molds in children and adults in Chile

Ricardo Rabagliati, Dona Benadof, Luis Thompson, Patricia García et autres

BACKGROUND: Invasive mold diseases (IMDs) are a severe complication of immunocompromised subjects and an emerging problem among severely ill, apparently immunocompetent patients. The aim of this study was to describe the epidemiological and clinical features of IMDs in Chile. METHODS: Prospective study …

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Actividad in vitro de ceftazidima/avibactam contra aislados clínicos de Klebsiella pneumoniae resistente a carbapenémicos y comparación de técnicas de susceptibilidad

Valeria Quiroz, Lina María Rivas, Katherine Soto, Valentina Sanfurgo et autres

ceftazidime/avibactam against carbapenem-resistant Klebsiella pneumoniae clinical isolates and comparison of susceptibility methods

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Identificación de micobacterias no tuberculosas en red de agua potable domiciliaria en la Región Metropolitana de Chile

Marco Vásquez, María Elvira Balcells, Patricia García, Andrea I. Moreno‐Switt et autres

Declaramos que no existen conflictos de interés en el presente estudio.Los resultados y las conclusiones se presentan de manera objetiva y sin influencia de intereses externos.

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Development of a robust FT-IR typing system for Salmonella enterica , enhancing performance through hierarchical classification

Diego Fredes-García, Javiera Jiménez-Rodríguez, Alejandro Piña-Iturbe, Pablo Caballero-Díaz et autres

ABSTRACT Salmonella enterica is a leading cause of foodborne illnesses globally, with significant mortality rates, especially among vulnerable populations. Traditional serotyping methods for Salmonella are accurate but expensive, resource-intensive, and time-consuming, necessitating faster and more reliable alternatives. This study evaluates the IR …

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Geographic divergence of methicillin-resistant Staphylococcus aureus ST5-SCC mec I in the aftermath of a major earthquake and tsunami: impact of a plasmid harboring heavy metal resistance genes

José R W Martínez, Manuel Alcalde‐Rico, Estefanía Jara-Videla, Jinnethe Reyes et autres

ABSTRACT Methicillin-resistant Staphylococcus aureus (MRSA) is a major public health menace. The global spread of MRSA is characterized by successive waves of epidemic clones dominating specific geographical regions. The acquisition of genes encoding resistance to heavy metals (HMRGs) is thought to be …

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Salmonella enterica Serovar Abony Outbreak Caused by Clone of Reference Strain WDCM 00029, Chile, 2024

Alejandro Piña-Iturbe, Diego Fredes-García, Patricia García, Lorena Porte et autres

A Salmonella enterica serovar Abony outbreak occurred during January-April 2024 in Chile. Genomic evidence indicated that the outbreak strain was a clone of reference strain WDCM 00029, which is routinely used in microbiological quality control tests. When rare or unreported serovars cause …