Louis Jones

Maximizing binary interactome mapping with a minimal number of assays

Soon Gang Choi, Julien Olivet, Patricia Cassonnet, Pierre‐Olivier Vidalain et autres

Complementary assays are required to comprehensively map complex biological entities such as genomes, proteomes and interactome networks. However, how various assays can be optimally combined to approach completeness while maintaining high precision often remains unclear. Here, we propose a framework for binary …

us, be, fr, at, de, es (code pays fourni par la source)

Maximizing binary interactome mapping with a minimal number of assays

Soon Gang Choi, Julien Olivet, Patricia Cassonnet, Pierre‐Olivier Vidalain et autres

Abstract Complementary assays are required to comprehensively map complex biological entities such as genomes, proteomes and interactome networks. However, how various assays can be optimally combined to approach completeness while maintaining high precision often remains unclear. Here, we propose a framework for …

us, fr, Maroc, be, at, de, es (code pays fourni par la source)

Towards an “assayome” for binary interactome mapping

Soon Gang Choi, Julien Olivet, Patricia Cassonnet, Pierre‐Olivier Vidalain et autres

ABSTRACT Complementary assays are required to comprehensively map complex biological entities such as genomes, proteomes and interactome networks. However, how various assays can be optimally combined to approach completeness while maintaining high precision often remains unclear. Here, we propose the concept of …

us, be, fr, Maroc, es (code pays fourni par la source)

Seasonal Genetic Drift of Human Influenza A Virus Quasispecies Revealed by Deep Sequencing

Cyril Barbezange, Louis Jones, Hervé Blanc, Ofer Isakov et autres

After a pandemic wave in 2009 following their introduction in the human population, the H1N1pdm09 viruses replaced the previously circulating, pre-pandemic H1N1 virus and, along with H3N2 viruses, are now responsible for the seasonal influenza type A epidemics. So far, the evolutionary …

fr, il (code pays fourni par la source)

The SRC-family tyrosine kinase HCK shapes the landscape of SKAP2 interactome

Jean‐François Bureau, Patricia Cassonnet, Laura Grange, Julien Dessapt et autres

// Jean-François Bureau 1, 2 , Patricia Cassonnet 3, 4, 5 , Laura Grange 1, 2 , Julien Dessapt 1, 2 , Louis Jones 3, 4, 5 , Caroline Demeret 3, 4, 5 , Anavaj Sakuntabhai 1, 2 and Yves Jacob 3, …

fr (code pays fourni par la source)

Comparative Profiling of Ubiquitin Proteasome System Interplay with Influenza A Virus PB2 Polymerase Protein Recapitulating Virus Evolution in Humans

Élise Biquand, Juline Poirson, Marwah Karim, Marion Declercq et autres

Influenza A viruses (IAVs) are responsible for mild-to-severe seasonal respiratory illness of public health concern worldwide, and the risk of avian strain outbreaks in humans is a constant threat. Elucidating the requisites of IAV adaptation to humans is thus of prime importance. …

fr (code pays fourni par la source)

Mapping the interactome of HPV E6 and E7 oncoproteins with the ubiquitin‐proteasome system

Juline Poirson, Élise Biquand, Marie‐Laure Straub, Patricia Cassonnet et autres

Protein ubiquitination and its reverse reaction, deubiquitination, regulate protein stability, protein binding activity, and their subcellular localization. These reactions are catalyzed by the enzymes E1, E2, and E3 ubiquitin (Ub) ligases and deubiquitinases (DUBs). The Ub-proteasome system (UPS) is targeted by viruses …

fr (code pays fourni par la source)

Whole genome-based population biology and epidemiological surveillance of Listeria monocytogenes

Alexandra Moura, Alexis Criscuolo, Hannes Pouseele, Mylène M. Maury et autres

fr, us, dk, gb, ca (code pays fourni par la source)

The genome of the yellow potato cyst nematode, Globodera rostochiensis, reveals in-sights into the bases of parasitism and virulence

Sebastian Eves‐van den Akker, Dominik R. Laetsch, Peter Thorpe, Catherine J. Lilley et autres

The yellow potato cyst nematode Globodera rostochiensis is a devastating plant pathogen of global economic importance, classified into pathotypes of different plant resistance-breaking phenotypes. G. rostochiensis secretes effectors, some of which were acquired by horizontal gene transfer (HGT), from pharyngeal glands into …

gb, fr, nl, az (code pays fourni par la source)

A Field-Proven Yeast Two-Hybrid Protocol Used to Identify Coronavirus–Host Protein–Protein Interactions

Pierre‐Olivier Vidalain, Yves Jacob, Marne C. Hagemeijer, Louis Jones et autres

fr, nl, us (code pays fourni par la source)

Genomic Definition of Hypervirulent and Multidrug-Resistant Klebsiella pneumoniae Clonal Groups

Suzanne Bialek-Davenet, Alexis Criscuolo, Florent Ailloud, Virginie Passet et autres

Multidrug-resistant and highly virulent Klebsiella pneumoniae isolates are emerging, but the clonal groups (CGs) corresponding to these high-risk strains have remained imprecisely defined. We aimed to identify K. pneumoniae CGs on the basis of genome-wide sequence variation and to provide a simple …

fr, Maroc, Mali (code pays fourni par la source)

Comparative analysis of virus–host interactomes with a mammalian high-throughput protein complementation assay based on Gaussia princeps luciferase

Grégory Neveu, Patricia Cassonnet, Pierre‐Olivier Vidalain, Caroline Rolloy et autres

fr, us (code pays fourni par la source)