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Profil bibliographique

Hanne Mette Hoffmann

Informations fournies par OpenAlex. Research Africa ne déduit ni nationalité, ni poste, ni coordonnées personnelles.

82Publications signalées
1194Citations signalées
1Affiliations récentes

Les institutions déclarées

Les domaines associés

Circadian rhythm and melatoninHypothalamic control of reproductive hormonesBirth, Development, and HealthGenetic and Clinical Aspects of Sex Determination and Chromosomal AbnormalitiesNeuroendocrine regulation and behavior

Les publications récentes

Accès ouvert 2026 article OpenAlex

Time of day of induction impacts the total duration of labor

Kylie Cataldo, Robert Long, Isoken Olomu, Rene Cortese et autres

BACKGROUND: Spontaneous labor onset peaks during the late evening and early morning hours, indicating a circadian influence on parturition. However, the effect of the time of day of labor induction on labor duration and obstetrical outcomes remains unexplored. We hypothesize that the …

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3 citations American Journal of Obstetrics & Gynecology MFM
Accès ouvert 2025 article OpenAlex

Interaction between time-of-day and oxytocin efficacy in mice and humans with and without gestational diabetes

Thu Van-Quynh Duong, Alexandra M. Yaw, Guoli Zhou, Niharika Sinha et autres

Due to significant risks of peripartum complications, pregnancies complicated by diabetes often require labor induction or augmentation with synthetic oxytocin. However, the efficacy of oxytocin is often compromised in diabetic pregnancies. Given that diabetes deregulates the body’s circadian timekeeping system, our objective …

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2 citations Molecular Metabolism
Accès ouvert 2025 article OpenAlex

MON-168 Validation Of A Novel Mouse Placenta Explant Protocol For Studying Circadian Rhythms In Early, Mid, And Late Pregnancy

Alexandra M. Yaw, Kierra Jursch, Jessica Sora Lee, Hanne Mette Hoffmann

Abstract Disclosure: A.M. Yaw: None. K. Jursch: None. J.S. Lee: None. H.M. Hoffmann: None. Preeclampsia, a hypertensive disorder of pregnancy, remains a leading cause of maternal and fetal mortality. Placental dysfunction is a central factor in the etiology of preeclampsia and is …

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0 citations Journal of the Endocrine Society
Accès ouvert 2025 article OpenAlex

MON-167 A Mouse Model of Chronic Shiftwork-like Lighting Exposure Identifies Adverse Pregnancy Outcomes in Female Mice Independent of Estrous Cycle Regularity

Alexandra M. Yaw, Brooke Van Loh, Autumn K. McLane-Svoboda, Krystal Jang et autres

Abstract Disclosure: A.M. Yaw: None. B. Van Loh: None. A.K. McLane-Svoboda: None. K. Jang: None. K. Jursch: None. D. Nguyen: None. H.M. Hoffmann: None. Nighttime and rotating shiftwork are linked to numerous health risks, including disrupted menstrual cycles and adverse pregnancy outcomes; …

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0 citations Journal of the Endocrine Society
Accès ouvert 2025 article OpenAlex

Reflections on the NIEHS Virtual Consortium funding mechanism (ViCTER) and what it has taught us about the future of transdisciplinary science

Almudena Veiga‐Lopez, Hanna Elizabeth Stevens, Matthew D. Rand, Ronald B. Tjalkens et autres

In environmental health science, collaboration across disciplines is often encouraged but rarely specifically solicited through funding mechanisms. The United States National Institute of Environmental Health Sciences (NIEHS) Virtual Consortium for Translational/Transdisciplinary Environmental Research (ViCTER) program fostered and promoted early-stage transdisciplinary collaborations among …

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3 citations Toxicology
Accès ouvert 2025 article OpenAlex

Light quality and time in shelter modulate behavior and cortisol in the domestic cat (Felis catus)

Alexandra M. Yaw, Mary E Gardella, Jacquelyn Jacobs, Hanne Mette Hoffmann

) increases risk of disease, promotes undesirable behaviors, and is associated with reduced adoptions from shelters. To determine how light properties impact stress and behavioral activity patterns in cats, the effects of light intensity and composition were tested in 101 male and …

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1 citation iScience
2025 article OpenAlex

The Transcription Factors Six3 and Six6 have Different Functions in Circadian Regulation of the Adult Mouse SCN

Brooke M. Van Loh, Geneva A Dunn, Lauren E. Chun, Meera M. Patel et autres

Circadian rhythms are processes that repeat approximately every 24 hours and are regulated by the suprachiasmatic nucleus (SCN) in the hypothalamus of the brain. The regulation of circadian rhythms and downstream processes is highly dependent on the proper development and function of …

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0 citations Physiology
2025 article OpenAlex

Blood Pressure Circadian Rhythm and Pregnancy Outcomes in High-Fat Diet-Fed Dahl Salt-Sensitive Rat

Lauren J. Kim, Alexandra M. Yaw, Linda A. Nduwimana, Bryce M. Gilbert et autres

Maternal obesity is a major risk factor for hypertensive disorders of pregnancy (HDP), a leading cause of maternal and fetal mortality worldwide. Disrupted blood pressure (BP) circadian rhythm may occur in association with obesity and HDP. Yet, the interplay between maternal adiposity …

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0 citations Physiology
Accès ouvert 2024 preprint OpenAlex

Interaction between time-of-day and oxytocin efficacy in mice and humans with and without gestational diabetes

Thu Van-Quynh Duong, Alexandra M. Yaw, Guoli Zhou, Niharika Sina et autres

Abstract Management of labor in women with diabetes is challenging due to the high risk of peri- and postpartum complications. To avoid cesarean section and assist with labor progression, Pitocin, a synthetic oxytocin, is frequently used to induce and augment labor. However, …

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1 citation bioRxiv (Cold Spring Harbor Laboratory)
Accès ouvert 2024 article OpenAlex

7503 Light Composition Alters Feline Stress in a Shelter Environment

Alexandra M. Yaw, Mary E Gardella, Jacquelyn Jacobs, Hanne Mette Hoffmann

Abstract Disclosure: A.M. Yaw: None. M.E. Gardella: None. J. Jacobs: None. H.M. Hoffmann: None. Millions of cats enter animal shelters each year. Unfortunately, due to high numbers of cats entering shelters and limited physical housing space, over 50% of healthy and adoptable …

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0 citations Journal of the Endocrine Society
Accès ouvert 2024 article OpenAlex

12209 Validation Of A Novel Placenta Explant Protocol For Studying Circadian Rhythms In The Mouse Placenta In Early, Mid And Late Pregnancy

Jessica Sora Lee, Alexandra M. Yaw, Hanne Mette Hoffmann

Abstract Disclosure: J.S. Lee: None. A.M. Yaw: None. H.M. Hoffmann: None. Introduction: The placenta serves as an interface facilitating the exchange of essential nutrients and oxygen between the mother and fetus. Preeclampsia, a complication of pregnancy driven by placental dysfunction, is one …

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0 citations Journal of the Endocrine Society

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