Chunxiang Feng

Engineered prostate-specific membrane antigen-targeted liposomal nanoplatform integrating near-infrared fluorescence, ultrasound, and magnetic resonance imaging for precision prostate cancer imaging

Kunlin Wu, Zhiye Liu, Junquan Hu, Teng Li et autres

• PSMA-targeted liposomes co-loaded with ICG, PFP, and MnO 2 enable tri-modal imaging. • Tailored liposomal architecture synchronizes NIR fluorescence, US, and MRI signals. • Engineered surface boosts PSMA-specific tumor targeting and cellular internalization. • Tri-modal imaging demonstrates 4.6 × NIR and …

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Caspase recruiting domain-containing protein 11 (CARD11) serves as a therapeutic biomarker for the drug therapies of clear cell renal cell carcinoma

Kaiwen Tian, Yanlin Tang, Qianian Wang, Chujin Ye et autres

Abstract Clear cell renal cell carcinoma (ccRCC) belongs to the ten most diagnosed cancer types worldwide. Novel drug therapies are introduced and beneficial to the advanced ccRCC but lack effective biomarkers for the therapeutic response. Tumor-infiltrating immune cells and gene signatures are …

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Alkaline phosphatase combines with CT factors for differentiating small (≤ 4 cm) fat-poor angiomyolipoma from renal cell carcinoma: a multiple quantitative tool

Tianming Peng, Junhong Fan, Binyang Xie, Qianqian Wang et autres

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Integrated bioinformatical analysis, machine learning and in vitro experiment-identified m6A subtype, and predictive drug target signatures for diagnosing renal fibrosis

Chunxiang Feng, Zhixian Wang, Chang Liu, Shiliang Liu et autres

Renal biopsy is the gold standard for defining renal fibrosis which causes calcium deposits in the kidneys. Persistent calcium deposition leads to kidney inflammation, cell necrosis, and is related to serious kidney diseases. However, it is invasive and involves the risk of …

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