Stanko Srčič

Doc. dr. Andrej Umek, farmakognost (1951-2025)

Stanko Srčič

Blueprint for a Universal Artificial Intelligence-Driven Digital Platform in Healthcare and Life Sciences – From Vision to Implementation (Preprint)

Rahela Penovski, Stanko Srčič, Reinhold Scherer

BACKGROUND Digital transformation in healthcare and life sciences has accelerated through data-driven innovations, Artificial Intelligence (AI), and automation. Despite progress, digital platforms remain fragmented, limiting care continuity, research integration, and operational efficiency. A universal AI-driven digital platform could offer transformative potential by …

The landscape of Artificial Intelligence Driven Digital Platforms in Healthcare and Life Sciences: A Scoping Review Towards Universal Integration (Preprint)

Rahela Penovski, Stanko Srčič, Reinhold Scherer

BACKGROUND Digital platforms are transforming healthcare and life sciences by enhancing operational efficiency, improving patient outcomes, and accelerating product development and market access. These platforms facilitate telemedicine, remote patient monitoring, and data-driven care delivery, while in life sciences, they streamline research, optimize …

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Effect of moisture on solid state stability

Stanko Srčič, Zoran Lavrič

Water is omnipresent during pharmaceutical product manufacturing and may interact with the drug substance, excipients, and the drug product in either solvent or vapor form, resulting in several physico-chemical changes, ultimately affecting product performance. Therefore, understanding the mechanisms behind such moisture-induced changes …

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Solubility of Luteolin and Other Polyphenolic Compounds in Water, Nonpolar, Polar Aprotic and Protic Solvents by Applying FTIR/HPLC

Saša Rajhard, Lucija Hladnik, Filipa A. Vicente, Stanko Srčič et autres

In recent years, flavonoids have become a highly researched topic due to their health beneficial effects. Since flavonoids’ solubility plays a significant role in their use in pharmaceutical, food, biological, and chemical areas, the determination of suitable solvents is crucial. Fourier transform …

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Multivariate analysis for optimization and validation of the industrial tablet-manufacturing process

Marcel Prikeržnik, Stanko Srčič

OBJECTIVE: This study aimed initially to optimize the industrial tablet-manufacturing process using multivariate analysis, and then to validate the model obtained. The study also provides a comprehensive review of the influence of different factors on relevant biopharmaceutical parameters. SIGNIFICANCE: This is the …

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Utilization of Ethylcellulose Microparticles with Rupatadine Fumarate in Designing Orodispersible Minitablets with Taste Masking Effect

Katarzyna Wasilewska, Patrycja Ciosek, Joanna Lenik, Stanko Srčič et autres

Minitablets in orodispersible form constitute a flexible drug delivery tool for paediatric and geriatric population as they eliminate the risk of chocking and do not require drinking water in the application. Due to their direct contact with taste buds, taste sensation is …

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Step-wise approach to developing a scale-independent design space for functional tablet coating process

Veronika Debevec, Tijana Stanić Ljubin, Žiga Jeraj, Tanja Rozman Peterka et autres

The objective of this study is to present a practical example of a scale-independent design space development using a step-wise approach. A detailed description of the development process with a systematic outline of the main steps is provided. Design space is developed …

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Multivariate analysis for optimization and validation of the industrial tablet-manufacturing process

Marcel Prikeržnik, Stanko Srčič

This study aimed initially to optimize the industrial tablet-manufacturing process using multivariate analysis, and then to validate the model obtained. The study also provides a comprehensive review of the influence of different factors on relevant biopharmaceutical parameters. This is the first time …

Correlation matrix

Marcel Prikeržnik, Stanko Srčič

Correlation matrix

Evaluation of ATP bioluminescence for monitoring surface hygiene in a hospital pharmacy cleanroom

Mateja Tršan, Matej Vehovc, Katja Seme, Stanko Srčič

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Correction to: Impact of Buffer, Protein Concentration and Sucrose Addition on the Aggregation and Particle Formation during Freezing and Thawing

Astrid Hauptmann, Katja Podgoršek, Drago Kuzman, Stanko Srčič et autres

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