Jeffrey B. Doty

Orthopoxvirus Antibodies in Feral Mammals in Mpox Outbreak Areas, Nigeria, 2021–2022

Adeyinka Jeremy Adedeji, Clement Adebajo Meseko, Ismaila Ademola Shittu, Nanven Maurice et autres

We analyzed tissue and serum samples from 124 wild animals from communities with confirmed mpox cases in Nigeria. Tissue samples were PCR-negative, but serum samples from 8 animals (6.45%)-3 feral cats, 4 giant pouched rats, and 1 shrew-revealed Orthopoxvirus antibodies, suggesting these …

Historic and contemporary museum specimens implicate Northern Red-backed Vole ( Clethrionomys rutilus ) as borealpox host as early as 1990s

Maya M. Juman, Jeffrey B. Doty, Clint N. Morgan, Audrey M. Matheny et autres

Abstract Borealpox virus (BRPV; formerly Alaskapox) is an orthopoxvirus that has caused seven reported human infections in Alaska since 2015, including a fatal case in 2023. The natural reservoir of BRPV is unknown, although previous investigations have raised the possibility of wild …

us, gb (code pays fourni par la source)

A cross-sectional serological study of bats in the United States Virgin Islands during 2019 to 2020 reveals no evidence of rabies virus exposure

A. Springer Browne, Hannah M. Cranford, Danielle Fibikar, Clint N. Morgan et autres

Bats are a known reservoir of rabies virus in 10 Caribbean nations. A cross-sectional survey of five species of native bats on U.S. Virgin Islands of St. Croix, St. John, and St. Thomas was performed during September 2019–January 2020. Serological testing was …

us, vi (code pays fourni par la source)

Six Cases of Borealpox and Evidence of a Zoonotic Source: Alaska, 2020–2023

Eric Q. Mooring, Julia H. Rogers, Florence Whitehill, Zachary R. Werle et autres

BACKGROUND: Borealpox virus (previously known as Alaskapox virus) is an Orthopoxvirus species first identified in a patient living near Fairbanks, Alaska, in 2015; the source of the patient's infection was unknown. Six additional borealpox cases have been identified through 2023. METHODS: We …

us, Ouganda (code pays fourni par la source)

Fatal Borealpox in an Immunosuppressed Patient Treated With Antivirals and Vaccinia Immunoglobulin—Alaska, 2023

Julia H. Rogers, Benjamin P. Westley, Thomas Mego, K. David Newell et autres

BACKGROUND: Borealpox virus (BRPV, formerly known as Alaskapox virus) is a zoonotic member of the Orthopoxvirus genus first identified in a person in 2015. In the 6 patients with infection previously observed, BRPV involved mild and self-limiting illness. We report the first …

us, Ouganda (code pays fourni par la source)

One Health Investigation into Mpox and Pets, United States

Clint N. Morgan, Natalie M. Wendling, Nicolle Baird, C. Kling et autres

Monkeypox virus (MPXV) is zoonotic and capable of infecting many mammal species. However, whether common companion animals are susceptible to MPXV infection is unclear. During July 2022-March 2023, we collected animal and environmental swab samples within homes of confirmed human mpox case-patients …

Experimental inoculation of pigs with monkeypox virus results in productive infection and transmission to sentinels

Emily K. Mantlo, Jessie D. Trujillo, Natasha N. Gaudreault, Igor Morozov et autres

Monkeypox virus (MPXV) is a re-emerging zoonotic poxvirus responsible for producing skin lesions in humans. Endemic in sub-Saharan Africa, the 2022 outbreak with a clade IIb strain has resulted in ongoing sustained transmission of the virus worldwide. MPXV has a relatively wide …

us, Ouganda (code pays fourni par la source)

Co-Circulating Monkeypox and Swinepox Viruses, Democratic Republic of the Congo, 2022

Thierry Kalonji-Mukendi, Emile Malembi, Jean Paul Matela, Toutou Likafi et autres

In September 2022, deaths of pigs manifesting pox-like lesions caused by swinepox virus were reported in Tshuapa Province, Democratic Republic of the Congo. Two human mpox cases were found concurrently in the surrounding community. Specific diagnostics and robust sequencing are needed to …

République démocratique du Congo, us, be (code pays fourni par la source)

Clinical Manifestations of an Outbreak of Monkeypox Virus in Captive Chimpanzees in Cameroon, 2016

Stephanie Brien, Matthew LeBreton, Jeffrey B. Doty, Matthew R. Mauldin et autres

Monkeypox virus (MPXV) is a reemerging virus of global concern. An outbreak of clade I MPXV affected 20 captive chimpanzees in Cameroon in 2016. We describe the epidemiology, virology, phylogenetics, and clinical progression of this outbreak. Clinical signs included exanthema, facial swelling, …

gb, us, Cameroun (code pays fourni par la source)

The CDC Domestic Mpox Response — United States, 2022–2023

Jennifer H. McQuiston, Christopher R. Braden, Michael D. Bowen, Andrea M. McCollum et autres

A U.S. government response was initiated, and CDC coordinated activities with the White House, the U.S. Department of Health and Human Services, and many other federal, state, and local partners. CDC quickly adapted surveillance systems, diagnostic tests, vaccines, therapeutics, grants, and communication …

us (code pays fourni par la source)

Orthopoxvirus Circulation in an Endemic Area in Brazil: Investigation of Infections in Small Mammals during an Absence of Outbreaks

Iago José da Silva Domingos, Kamila Lorene Soares Rocha, Jessica M. Graciano, Lara Ribeiro de Almeida et autres

Vaccinia virus (VACV) is the causative agent of an emerging viral zoonosis called bovine vaccinia (BV). Several studies have documented characteristics of VACV infections in Brazil; however, the manner in which this virus is maintained in wildlife remains unknown. This work investigated …

br, us (code pays fourni par la source)

Orthopoxvirus Infections in Rodents, Nigeria, 2018–2019

Clement Adebajo Meseko, Adeyinka Jeremy Adedeji, Ismaila Ademola Shittu, Emmanuel Obishakin et autres

To investigate animal reservoirs of monkeypox virus in Nigeria, we sampled 240 rodents during 2018-2019. Molecular (real-time PCR) and serologic (IgM) evidence indicated orthopoxvirus infections, but presence of monkeypox virus was not confirmed. These results can be used to develop public health …

us, Nigéria (code pays fourni par la source)